Is the blood glucose concentration related to the incidence of large for gestational age infants in patients with gestational and insulin requiring diabetes mellitus?

1995 ◽  
Vol 2 (2) ◽  
pp. 193
Author(s):  
C BARADA
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Gestational Age ◽  
Glucose Concentration ◽  
Blood Glucose Concentration ◽  
Large For Gestational Age

Can the diabetic diet be improved?

1979 ◽  
Vol 17 (22) ◽  
pp. 85-87
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Glucose Concentration ◽  
Blood Glucose Concentration ◽  
Cardiovascular Complications ◽  
Fibre Content ◽  
Dietary Control ◽  
Carbohydrate Restriction ◽  
Hypoglycaemic Agents ◽  
Diabetic Diet

Dietary control is a central part of management of diabetes mellitus. Traditional advice is primarily concerned with carbohydrate restriction, calorie control and the timing of meals. The importance of the fat and fibre content is largely ignored although fats might influence the development of cardiovascular complications and fibre the blood glucose concentration and the response to hypoglycaemic agents. The composition of the diabetic diet needs reappraisal.

scholarly journals Syzygium polyanthum protects against diabetic cardiac apoptosis in the chronic diabetes mellitus

2020 ◽  
Vol 5 (1) ◽  
pp. 16
Author(s):  
Flori R Sari ◽  
Hari Hendarto ◽  
Chris Adhiyanto ◽  
Fadhlurrahman Ananditya ◽  
Irfiani N ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Glucose Concentration ◽  
Blood Glucose Concentration ◽  
Cholesterol Concentration ◽  
Diabetic Rat ◽  
Beneficial Role ◽  
Cell Death Pathway ◽  
Cardiac Apoptosis ◽  
Persistent Hyperglycemia

Introduction: Hyperglycemia has become the main characteristic of diabetes mellitus. Persistent hyperglycemia directly activates cell death pathway that plays pivotal role in the diabetic complication including diabetic cardiomyopathy. Syzygium polyanthum plays a beneficial role in the diabetic condition by reducing the blood glucose concentration, however the role of this natural resources in preventing further complication of diabetes mellitus has not been revealed fully yet.Method: Syzygium polyanthum dry extract (300 mg/kg body weight) were given daily for 28 days in the streptozotocin-induced diabetic rat. Measurement of blood glucose concentration were done three times during the study, meanwhile cholesterol concentration, myocardial diameter and cardiac apoptosis were measured on the day 28 of the study. Cardiac apoptosis was analyzed by the TdT-mediated dUTP nick end-labelling (TUNEL Assay).Results: Persistent hyperglycemia as well as cardiac apoptosis was significantly observed in the diabetic rat (D) on the day 28 of the study confronted to the normal rat (N). Interestingly, significant blood glucose reduction in concomitant with a lesser concentration of cardiac apoptosis were observed in the diabetic rat received 28 days Syzygium polyanthum extract (DS) confronted to the D rat. Additionally, lower plasma cholesterol concentration was significantly observed in the DS rat confronted to the D rat.Discussion: Significant cardiac apoptosis was observed in consistent with persistent hyperglycemia in the D rat as well as lesser cardiac apoptosis was observed in accordance with blood glucose concentration reduction in the DS rat. Therefore, Syzygium polyanthum may play beneficial role in the diabetic-associated cardiac apoptosis through its direct effect on the blood glucose concentration reduction. However further analysis should be done to fully elucidate the apoptotic pathway that involved.International Journal of Human and Health Sciences Vol. 05 No. 01 January’21 Page: 16-21

Production of diabetes mellitus in the duck by insulin antibodies

1964 ◽  
Vol 206 (1) ◽  
pp. 133-135 ◽  
Author(s):  
I. Arthur Mirsky ◽  
Robert Jinks ◽  
Gladys Perisutti
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Intravenous Injection ◽  
Glucose Concentration ◽  
Blood Glucose Concentration ◽  
Insulin Antibodies ◽  
Insulin Insufficiency

The intravenous injection of anti-insulin serum produces an immediate increase in the blood glucose concentration of both normal and presumably "depancreatized" ducks. Whereas the blood glucose of the normal ducks returns to the preinjection concentration within 3.5 hr, the hyperglycemia of the depancreatized ducks persists for more than 5 hr. The response is attributed to an acute insulin insufficiency induced by insulin antibodies. Accordingly, insulin is as essential to the regulation of the blood glucose of the duck as it is to that of mammals. The data from depancreatized ducks suggest the presence of a remnant of splenic lobe of the pancreas or some extrapancreatic source of insulin.

The effect of premixed insulin to blood glucose concentration in patients with type 2 diabetes mellitus

2020 ◽  
Vol 30 (6) ◽  
Author(s):  
Arina D. Puspitasari ◽  
Hayu Kusuma ◽  
Dinda M.N. Ratri ◽  
Cahyo Wibisono ◽  
Budi Suprapti
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Blood Glucose ◽  
Glucose Concentration ◽  
Blood Glucose Concentration ◽  
Postprandial Blood Glucose ◽  
Premixed Insulin ◽  
Acting Insulin ◽  
Blood Glucose Concentrations

AbstractBackgroundOne of the therapies used to treat type 2 diabetes mellitus (T2DM) disease is combination insulin which consists of rapid-acting insulin and intermediate-acting insulin (premixed). This study aimed to examine the profile of premixed insulin related to blood glucose concentration and to identify the drug interactions due to the combination of premixed insulin with other drugs taken by T2DM patients.MethodsThis study was a prospective observational study with cross-sectional data that were analyzed descriptively. The respondents invited were T2DM patients with or without complication or comorbid disease who received premixed insulin with or without a combination of oral antidiabetic therapy in the Outpatient Unit of Universitas Airlangga Hospital, Surabaya. The research instruments used are data sheet, patient medical record, and fasting and postprandial blood glucose concentration.ResultsA total of 118 patients received premixed insulin therapy, but only 80 patients were included in the inclusion criteria. Based on types of insulin, the combination of 30% aspart and 70% protamine aspart was used by 91.25% T2DM patients, and a combination of 25% insulin lispro and 75% protamine lispro was used by 8.75% T2DM patients. There were 30.3% of patients who could achieve the target of 80–130 mg/dL in fasting blood glucose concentrations, and 35.1% of patients achieved the target of ≤180 mg/dL in postprandial blood glucose concentration. Drug interactions may occur in patients who use premixed insulin with glimepiride, lisinopril, fenofibrate, candesartan, irbesartan, and gemfibrozil.ConclusionsIn this study, premixed insulin have not reached the target of fasting and postprandial blood glucose concentrations in most patients.

scholarly journals Update on insulin treatment of dogs and cats with non-complicated diabetes mellitus

2018 ◽  
Vol 67 (2) ◽  
pp. 83
Author(s):  
M. N. SARIDOMICHELAKIS ◽  
M. K. CHATZIS
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Glucose Concentration ◽  
Insulin Treatment ◽  
Blood Glucose Concentration ◽  
Insulin Dose ◽  
Glucose Monitoring ◽  
Insulin Administration ◽  
Tight Control ◽  
Insulin Glargin

Diabetes mellitus is a common endocrine disease of dogs and cats. Treatment is mainly based on insulin administration and dietary modifications. The aim of this review is to provide updated information on insulin treatment of dogs and cats with non-complicated diabetes mellitus. During the last years, there has been significant progress in the management of this disease, thanks to the use of long-acting insulin preparations that do not cause pronounced fluctuations of blood glucose concentrations (insulin glargin and detemir) and because of the widespread use of home glucose monitoring by the owners of diabetic pets. Home glucose monitoring is based on capillary blood sampling from the ear pinnae or the foot pad and measurement of blood glucose concentration with a portable blood glucose meter. This can be done periodically (e.g. every week) to replace the traditional in-clinic blood glucose curve; in this case, blood glucose concentration is measured just before the morning insulin administration and then every 1-2 hours until the next dose (usually for 12 hours). Furthermore, especially for the cat, home glucose monitoring can be performed 3-5 times per day, on a daily basis, in order to safely adjust insulin dose and achieve tight control of hyperglycemia (i.e. blood glucose concentration between 50 and 200 mg dl-1 throughout the day). The combination of dietary management, of insulin glargine or detemir administration and of the tight control of hyperglycemia has substantially increased the proportion of cats that enter into temporal or permanent diabetic remission and can be further managed without insulin. Another important achievement is the use of continuous glucose monitoring systems to monitor interstitial fluid glucose concentrations. These devices can be used in the clinic and at home and they can measure glucose concentration every 5 minutes for up to 72 consecutive hours, thus facilitating optimal adjustment of insulin treatment.

Sign in / Sign up

Export Citation Format

Share Document