To establish, encourage and support a successful Information Therapy service in a developing country, it is essential to identify the preferences of patients, their information needs and attitudes toward CHI and Ix. In this paper, the author examines the attitudes of patients receiving health information and information prescription in Iran. An exploratory survey with an open interview and structured questionnaire was conducted to gather data from patients of educational hospitals and clinics in Tabriz, Iran. Tabriz’s diverse dialects and literacy levels mimic a developing nation, ensuring that the findings are transferable to other developing countries. The study reveals that patients’ information needs are generally related to basic issues of health. The level of literacy impacts neither the demand for health information nor the patients’ preferred channel to receive CHI and information prescription. A localized approach, considering the socioeconomic and cultural aspects of a developing country like Iran and its limitation in using applications of information and communication technology, would make the Information Therapy and Consumer Health Information Services successful.