MOLECULAR AND CHROMOSOMAL CHANGES DURING MOUSE MAMMARY TUMOR DEVELOPMENT

1991 ◽  
pp. 214
Author(s):  
R.L. ULLRICH ◽  
R.J. PRESTON ◽  
W.K. YANG ◽  
K.N. NIKBAKHT ◽  
S.C. McKARNES
Keyword(s):  
Mammary Tumor ◽  
Tumor Development ◽  
Mouse Mammary Tumor ◽  
Chromosomal Changes

scholarly journals Jnk2 Effects on Tumor Development, Genetic Instability and Replicative Stress in an Oncogene-Driven Mouse Mammary Tumor Model

PLoS ONE ◽  
2010 ◽  
Vol 5 (5) ◽  
pp. e10443 ◽  
Author(s):  
Peila Chen ◽  
Jamye F. O'Neal ◽  
Nancy D. Ebelt ◽  
Michael A. Cantrell ◽  
Shreya Mitra ◽  
...  
Keyword(s):  
Mammary Tumor ◽  
Genetic Instability ◽  
Tumor Development ◽  
Tumor Model ◽  
Replicative Stress ◽  
Mouse Mammary Tumor ◽  
Mammary Tumor Model ◽  
Mouse Mammary Tumor Model

scholarly journals Tumor-associated antigens identified early in mouse mammary tumor development can be effective vaccine targets

Vaccine ◽  
2019 ◽  
Vol 37 (27) ◽  
pp. 3552-3561 ◽  
Author(s):  
Sasha E. Stanton ◽  
Ekram Gad ◽  
Lauren R. Corulli ◽  
Hailing Lu ◽  
Mary L. Disis
Keyword(s):  
Mammary Tumor ◽  
Tumor Development ◽  
Effective Vaccine ◽  
Tumor Associated Antigens ◽  
Mouse Mammary Tumor

scholarly journals A Novel Mechanism of Resistance to Mouse Mammary Tumor Virus Infection

2000 ◽  
Vol 74 (6) ◽  
pp. 2752-2759 ◽  
Author(s):  
Tatyana V. Golovkina
Keyword(s):  
Mammary Gland ◽  
Mammary Tumor ◽  
Mouse Mammary Tumor Virus ◽  
Inbred Mice ◽  
Tumor Development ◽  
Mammary Glands ◽  
Mammary Tissue ◽  
Mammary Tumor Virus ◽  
Mouse Mammary Tumor ◽  
Tumor Virus

ABSTRACT Exogenous mouse mammary tumor virus (MMTV) is carried from the gut of suckling pups to the mammary glands by lymphocytes and induces mammary gland tumors. MMTV-induced tumor incidence in inbred mice of different strains ranges from 0 to as high as 100%. For example, mice of the C3H/HeN strain are highly susceptible, whereas mice of the I/LnJ strain are highly resistant. Of the different factors that together determine the susceptibility of mice to development of MMTV-induced mammary tumors, genetic elements play a major role, although very few genes that determine a susceptibility-resistance phenotype have been identified so far. Our data indicate that MMTV fails to infect mammary glands in I/LnJ mice foster nursed on viremic C3H/HeN females, even though the I/LnJ mammary tissue is not refractory to MMTV infection. Lymphocytes from fostered I/LnJ mice contained integrated MMTV proviruses and shed virus but failed to establish infection in the mammary glands of susceptible syngeneic (I × C3H.JK)F1 females. Based on the susceptible-resistant phenotype distribution in N2 females, both MMTV mammary gland infection and mammary gland tumor development in I/LnJ mice are controlled by a single locus.

scholarly journals The R-Enantiomer of Ketorolac Delays Mammary Tumor Development in Mouse Mammary Tumor Virus-Polyoma Middle T Antigen (MMTV-PyMT) Mice

2018 ◽  
Vol 188 (2) ◽  
pp. 515-524 ◽  
Author(s):  
Amanda S. Peretti ◽  
Dayna Dominguez ◽  
Martha M. Grimes ◽  
Helen J. Hathaway ◽  
Eric R. Prossnitz ◽  
...  
Keyword(s):  
Mammary Tumor ◽  
Mouse Mammary Tumor Virus ◽  
Tumor Development ◽  
T Antigen ◽  
Mammary Tumor Virus ◽  
Mouse Mammary Tumor ◽  
Tumor Virus ◽  
Polyoma Middle T Antigen ◽  
Middle T Antigen
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