Immunomodulatory and antiinflammatory activities of terrestrial fungal polysaccharides: A review

AbstractPolysaccharides are biopolymers composed of simple sugars like glucose, galactose, mannose, fructose, etc. The major natural sources for the production of polysaccharides include plants and microorganisms. In the present work, four bacterial and two fungal polysaccharides (PS or EPS) were used for the modification and preservation of Pycnoporus sanguineus cellobiose dehydrogenase (CDH) activity. It was found that the presence of polysaccharide preparations clearly enhanced the stability of cellobiose dehydrogenase compared to the control value (4 °C). The highest stabilization effect was observed for CDH modified with Rh110EPS. Changes in the optimum pH in the samples of CDH incubated with the chosen polysaccharide modifiers were evidenced as well. The most significant effect was observed for Rh24EPS and Cu139PS (pH 3.5). Cyclic voltammetry used for the analysis of electrochemical parameters of modified CDH showed the highest peak values after 30 days of incubation with polysaccharides at 4 °C. In summary, natural polysaccharides seem to be an effective biotechnological tool for the modification of CDH activity to increase the possibilities of its practical applications in many fields of industry.

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Cytochemical Techniques Available for the Study of Fungal Polysaccharides

Fungal Antigens ◽

10.1007/978-1-4613-0773-0_3 ◽

1988 ◽

pp. 57-69

Author(s):

Joseph Schrevel

Keyword(s):

Fungal Polysaccharides

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Structure and Bioactivities of Fungal Polysaccharides

Polysaccharides ◽

10.1007/978-3-319-03751-6_28-1 ◽

2014 ◽

pp. 1-14 ◽

Cited By ~ 1

Author(s):

Muhammad Saeed Khan ◽

Xuewu Zhang ◽

Lijun You ◽

Xiong Fu ◽

Arshad Mehmood Abbasi

Keyword(s):

Fungal Polysaccharides

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Bioactive Fungal Polysaccharides and Polysaccharopeptides

Handbook of Fungal Biotechnology ◽

10.1201/9780203027356-30 ◽

2003 ◽

pp. 584-599

Keyword(s):

Fungal Polysaccharides

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Protective activity of the fungal polysaccharides against fusariosis

Plant Protection Science ◽

10.17221/10571-pps ◽

2017 ◽

Vol 38 (SI 2 - 6th Conf EFPP 2002) ◽

pp. 617-619 ◽

Cited By ~ 1

Author(s):

A. Šrobárová ◽

G. Kogan ◽

L. Tamas ◽

E. Machová

Keyword(s):

Cell Wall ◽

Antifungal Activity ◽

Defense Mechanisms ◽

Field Experiments ◽

Plant Protection ◽

Water Soluble ◽

Protective Activity ◽

Fresh Weight ◽

Fungal Polysaccharides ◽

Chitin And Chitosan

Most of the experiments carried out in the area of plant protection have used chitin and chitosan obtained from the crustacean chitin which production is rather expensive. In our study we have applied the chitin-glucan complex prepared from the waste mycelia of filamentous fungi, from baker’s yeast. Five different polysaccharides have been used for the preparation of water-soluble compounds and the assay of their antifungal activity against plant pathogen Fusarium oxysporum. In the field experiments, application of the polysaccharides led to the diminished infestation as well as to significantly increased productivity of fresh weight of the plants (tomato). The results demonstrated that application of the polysaccharides led to increased production of cell wall and some outher and intermembrane-bound proteins. Although the nature of the observed proteins has not been yet established, it can be speculated that they represent some enzymes involved in the antiinfective defense mechanisms in plants.

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