Measurement of Biomarkers of Oxidative Stress and Airway Inflammation in Exhaled Breath Condensate: Methodology and Potential Applications in Patients with COPD and Healthy Smokers

2013 ◽  
pp. 360-381 ◽  
Author(s):  
Paolo Montuschi
Keyword(s):  
Oxidative Stress ◽  
Airway Inflammation ◽  
Exhaled Breath Condensate ◽  
Exhaled Breath ◽  
Potential Applications ◽  
Breath Condensate ◽  
Biomarkers Of Oxidative Stress

Biomarkers of oxidative-stress and inflammation in exhaled breath condensate from hospital cleaners

Biomarkers ◽  
2015 ◽  
Vol 21 (2) ◽  
pp. 115-122 ◽  
Author(s):  
Enrico Casimirri ◽  
Mariarita Stendardo ◽  
Melissa Bonci ◽  
Roberta Andreoli ◽  
Barbara Bottazzi ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Exhaled Breath Condensate ◽  
Exhaled Breath ◽  
Breath Condensate ◽  
Biomarkers Of Oxidative Stress

Assessment of airway inflammation in chronic obstructive pulmonary disease: Biomarkers in exhaled breath condensate

2012 ◽  
Vol 153 (22) ◽  
pp. 843-851 ◽  
Author(s):  
Balázs Antus
Keyword(s):  
Oxidative Stress ◽  
Chronic Obstructive Pulmonary Disease ◽  
Airway Inflammation ◽  
Pulmonary Disease ◽  
Tissue Injury ◽  
Exhaled Breath Condensate ◽  
Chronic Obstructive ◽  
Exhaled Breath ◽  
Obstructive Pulmonary Disease ◽  
Breath Condensate

Airway inflammation plays a central role in the pathophysiology of chronic obstructive pulmonary disease. Exposure to cigarette smoke induces the recruitment of inflammatory cells in the airways, which in turn produces various cytokines, chemokines, proteases and pro-inflammatory mediators leading ultimately to increased oxidative stress, a protease/anti-protease imbalance and progressive lung tissue injury. Biomarkers may be useful in monitoring airway inflammation and oxidative stress, defining different phenotypes of the disease and evaluating the response of therapies. Exhaled breath condensate collection is a simple and completely non-invasive method of sampling the lower respiratory tract in humans. Exhaled breath condensate may be a rich source of pulmonary biomarkers including hydrogen peroxide, cytokines, metabolites of the arachidonic acid, nitric oxides and the pH. However, the concentration of these biomarkers is often very low, which may cause several problems in their detection. The clinical applicability of exhaled breath condensate biomarkers cannot be assessed until methods of sample collection and analysis have been standardized. Orv. Hetil., 2012, 153, 843–851.

Oxidative Stress Markers In The Exhaled Breath Condensate Of Children With OSA

2011 ◽  
Author(s):  
Athanasios Kaditis ◽  
Georgia Malakasioti ◽  
Emmanouel Alexopoulos ◽  
Vasiliki Varlami ◽  
Christina Befani ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Exhaled Breath Condensate ◽  
Exhaled Breath ◽  
Oxidative Stress Markers ◽  
Stress Markers ◽  
Breath Condensate
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