Optimal Levels of Oxygenation in Preterm Infants: Impact on Short- and Long-Term Outcomes

2008 ◽  
pp. 333-360
Author(s):  
Win Tin ◽  
Samir Gupta
2019 ◽  
Vol 20 (10) ◽  
pp. 963-969 ◽  
Author(s):  
Yoshihito Sasaki ◽  
Kaoru Ishikawa ◽  
Akira Yokoi ◽  
Tomoaki Ikeda ◽  
Kazuo Sengoku ◽  
...  

2013 ◽  
Vol 36 (4) ◽  
pp. 662-669 ◽  
Author(s):  
Bahia Abdallah ◽  
Lina Kurdahi Badr ◽  
Mirvat Hawwari

2011 ◽  
Vol 70 ◽  
pp. 614-614
Author(s):  
D Batra ◽  
S Ghavam ◽  
H Kirpalani ◽  
J Mercer ◽  
K Amir ◽  
...  

2019 ◽  
Vol 36 (13) ◽  
pp. 1382-1386 ◽  
Author(s):  
Yair Kasirer ◽  
Alona Bin-Nun ◽  
Ateret Raveh ◽  
Irina Schorrs ◽  
Francis B. Mimouni ◽  
...  

Objective Intravenous lipid infusions improve both short- and long-term outcomes of premature neonates. However, prolonged infusion of lipids has been implicated in the development of parenteral nutrition-associated cholestasis (PNAC). We speculated that the multicomponent SMOFlipid would be hepatoprotective against PNAC. Study Design This is a retrospective review comparing the incidence and severity of direct hyperbilirubinemia in preterm infants <1,500 g who were hospitalized for a minimum of 2 weeks during a 20-month period in which all preterm infants on total parenteral nutrition (TPN) received fat as Lipofundin with the following 20-month period in which all preterm infants on TPN received SMOFlipid. Results Infants in the SMOFlipid period had a lower incidence of PNAC (6 vs. 13%; p = 0.022), lower peak direct bilirubin levels (3.2 vs. 7.1 mg/dL; p = 0.018), and a shorter length of stay (51 vs. 60 days; p = 0.019). The relative risk of developing direct hyperbilirubinemia during the Lipofundin period was 2.22 (1.1–4.3) as compared with period 1; p = 0.018; NNT-14. Conclusion SMOFlipid was hepatoprotective in our population of preterm neonates <1,500 g receiving long-term TPN as compared with those receiving Lipofundin, despite similar levels of exposure to both intravenous lipid load and duration in the two groups.


2011 ◽  
Vol 70 ◽  
pp. 105-105
Author(s):  
D Batra ◽  
S Ghavam ◽  
H Kirpalani ◽  
J Mercer ◽  
K Amir ◽  
...  

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