An integrated fluorescence biosensor for microRNA detection based on exponential amplification reaction-triggered three-dimensional bipedal DNA walkers

2021 ◽  
Vol 1143 ◽  
pp. 157-165 ◽  
Author(s):  
Liu Yang ◽  
Jie Fang ◽  
Junjie Li ◽  
Xinying Ou ◽  
Li Zhang ◽  
...  
Nanoscale ◽  
2021 ◽  
Author(s):  
Hui Hu ◽  
Fu Zhou ◽  
Baojuan Wang ◽  
Xin Chang ◽  
Tianyue Dai ◽  
...  

Three dimensional (3D) DNA walkers possesses the potential as ideal candidates for signal transduction and amplification in bioassays. However, intracellularly autonomous operation of 3D DNA walkers is still limitedly implemented...


2021 ◽  
Author(s):  
Xin Liu ◽  
Fanyu Meng ◽  
Rui Sun ◽  
Kangnan Wang ◽  
Zhiqiang Yu ◽  
...  

Gold nanoparticle mediated bipedal DNA walkers are fabricated for logic gate operations responding to telomerase and miRNA.


2021 ◽  
Author(s):  
chaohui chen ◽  
Rongxiang He ◽  
Xiaoyun Liu ◽  
Zhengtao Zhang ◽  
Long Chen

MicroRNAs play important roles in disease diagnosis and therapy. However, current methods for microRNAs detection suffer from low sensitivity and can’t directly detect short microRNAs. Herein, we have developed a...


Nanoscale ◽  
2020 ◽  
Author(s):  
Dan Li ◽  
Enlai Yang ◽  
Zewei Luo ◽  
Qiyue Xie ◽  
Yixiang Duan

An enzyme-mediated universal fluorescence biosensor template for rapid detection of pathogen was developed based on the strategy of three-dimensional (3D) DNA walker and catalyzed hairpin assembly (CHA) reaction. In the...


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