scholarly journals Centerline Tracking for Quantification of Reverse Structural Remodeling of the Pulmonary Veins Following Cardiac Ablation Therapy

2012 ◽  
Vol 19 (11) ◽  
pp. 1332-1344 ◽  
Author(s):  
Maryam E. Rettmann ◽  
Mia S. Gunawan ◽  
David R. Holmes ◽  
Jerome F. Breen ◽  
Douglas L. Packer ◽  
...  
Keyword(s):  
Pulmonary Veins ◽  
Cardiac Ablation ◽  
Structural Remodeling ◽  
Ablation Therapy ◽  
Centerline Tracking

scholarly journals Measurements of the left atrium and pulmonary veins for analysis of reverse structural remodeling following cardiac ablation therapy

2015 ◽  
Vol 118 (2) ◽  
pp. 198-206 ◽  
Author(s):  
Maryam E. Rettmann ◽  
David R. Holmes III ◽  
Jerome F. Breen ◽  
Xin Ge ◽  
Ronald A. Karwoski ◽  
...  
Keyword(s):  
Left Atrium ◽  
Pulmonary Veins ◽  
Cardiac Ablation ◽  
Structural Remodeling ◽  
Ablation Therapy

Validation of geometric measurements of the left atrium and pulmonary veins for analysis of reverse structural remodeling following ablation therapy

2012 ◽  
Author(s):  
M. E. Rettmann ◽  
D. R. Holmes ◽  
M. S. Gunawan ◽  
X. Ge ◽  
R. A. Karwoski ◽  
...  
Keyword(s):  
Left Atrium ◽  
Pulmonary Veins ◽  
Structural Remodeling ◽  
Ablation Therapy

scholarly journals Design and Evaluation of a Catheter Contact-Force Controller for Cardiac Ablation Therapy

2016 ◽  
Vol 63 (11) ◽  
pp. 2301-2307 ◽  
Author(s):  
Daniel Gelman ◽  
Allan C. Skanes ◽  
Mohammad A. Tavallaei ◽  
Maria Drangova
Keyword(s):  
Contact Force ◽  
Cardiac Ablation ◽  
Ablation Therapy

scholarly journals Electroanatomical mapping and radiofrequency ablation of tachycardia originating in pulmonary vein in an adult patient

2011 ◽  
Vol 152 (34) ◽  
pp. 1374-1378
Author(s):  
Eszter Mária Végh ◽  
Gábor Széplaki ◽  
Szabolcs Szilágyi ◽  
István Osztheimer ◽  
Tamás Tahin ◽  
...  
Keyword(s):  
Pulmonary Vein ◽  
Coronary Sinus ◽  
Left Atrial ◽  
Therapeutic Option ◽  
Pulmonary Veins ◽  
Supraventricular Arrhythmia ◽  
Electroanatomical Mapping ◽  
Ablation Therapy ◽  
Coronary Sinus Catheter ◽  
Electrophysiological Examination

A 29-year-old male was admitted to our outpatient clinic because of palpitation and documented narrow QRS arrhythmia. Based on the ECG, supraventricular tachycardia was diagnosed, electrophysiological examination was indicated and ablation therapy was recommended. During positioning of the catheter the patient developed arrhythmia. On the coronary sinus catheter the activation spread from distal to proximal electrodes, suggesting left atrial origin. During atrial entrainment pacing long return cycle was observed and distal coronary sinus pacing resulted in a 15 ms longer cycle length than the arrhythmia. Therefore, the left atrial origin of the arrhythmia was confirmed and double transseptal puncture was performed. Lasso and irrigated tip catheter were introduced into the left atrium and electroanatomical mapping was performed with CARTO3 system. After electroanatomical mapping the origin of tachycardia was located proximally in the left superior pulmonary vein. Ablation was started at the earliest activation point, where acceleration was observed and the arrhythmia stopped after the first ablation. Pulmonary vein isolation was completed, and bidirectional block could be confirmed. After 30 minutes the arrhythmia was not inducible. During follow-up, Holter-examination was negative and the patient remained asymptomatic. The pulmonary vein tachycardia is a supraventricular arrhythmia that can occur at any age, but the diagnosis based on the ECG is not always simple. Detailed electroanatomical mapping is very important in the diagnosis of this type of arrhythmia, although it can be verified with conventional electrophysiological methods as well. Focal ablation may be a therapeutic option; however, total isolation of pulmonary veins can be more effective. Orv. Hetil., 2011, 152, 1374–1378.

Segmentation of left atrial intracardiac ultrasound images for image guided cardiac ablation therapy

2013 ◽  
Author(s):  
M. E. Rettmann ◽  
T. Stephens ◽  
D. R. Holmes ◽  
C. Linte ◽  
D. L. Packer ◽  
...  
Keyword(s):  
Left Atrial ◽  
Ultrasound Images ◽  
Cardiac Ablation ◽  
Ablation Therapy ◽  
Image Guided ◽  
Intracardiac Ultrasound

scholarly journals Hybrid Convergent Procedure for the Treatment of Persistent and Long-standing Persistent Atrial Fibrillation

2021 ◽  
Vol 10 (3) ◽  
pp. 198-204
Author(s):  
David B DeLurgio ◽  
Jaswinder S Gill ◽  
Syed Ahsan ◽  
Riyaz A Kaba ◽  
Kristen M Plasseraud ◽  
...  
Keyword(s):  
Multidisciplinary Approach ◽  
Pulmonary Veins ◽  
Persistent Atrial Fibrillation ◽  
Rhythm Control ◽  
Published Data ◽  
Future Directions ◽  
Ablation Therapy ◽  
Treatment Gaps ◽  
Made In

Recent advances have been made in AF treatment, including the role of early rhythm control and landmark clinical trials using ablation therapy. However, some treatment gaps remain, including the creation of durable lesions outside the pulmonary veins and effective treatment of longstanding persistent AF. A novel epicardial-endocardial ablation approach – the hybrid convergent procedure – was developed to combine surgical and catheter ablation techniques into a collaborative, multidisciplinary approach to managing AF. In this review, the authors discuss recently published data on hybrid convergent ablation, including results of the CONVERGE clinical trial, in the context of current challenges to treatment of persistent and long-standing persistent AF. The review also aims to provide perspective on outstanding questions and future directions in this area.

scholarly journals Pathology Approaches to Determine Safety and Efficacy of Cardiac Ablation Catheters

2019 ◽  
Vol 47 (3) ◽  
pp. 311-328 ◽  
Author(s):  
William C. Stoffregen ◽  
Serge D. Rousselle ◽  
Marian K. Rippy
Keyword(s):  
Cardiac Electrophysiology ◽  
Pulmonary Veins ◽  
Conduction Block ◽  
Supporting Evidence ◽  
Preclinical Studies ◽  
Cardiac Ablation ◽  
Safety And Efficacy ◽  
Adjacent Structures ◽  
Circumferential Distribution ◽  
Pathology Data

Cardiac electrophysiology utilizes nonimplantable, catheter-based devices for diagnosis and treatment of arrhythmias as well as electroanatomical mapping of cardiac chambers. Gross pathology and histopathological assessments in preclinical studies play critical roles in determining the safety and efficacy of cardiac ablation systems used to treat tachyarrhythmias. The pathologist must assess ablation sites, adjacent structures and organs, and downstream organs to characterize the effects of the ablation treatment and determine whether adverse local reactions, collateral injury, or downstream thromboembolism are present. Histopathological assessment serves as an adjunct to electroanatomical data in determining efficacy in preclinical studies. Histopathology is the standard in definitively demonstrating transmurality of ablation lesions, which is necessary for complete conduction block, as well as showing the linear or circumferential distribution of a contiguous, transmural ablation lesion necessary for electroanatomical isolation of entire target structures such as pulmonary veins and the cavotricuspid isthmus, which are involved in propagating certain arrhythmias. This article will detail gross and histological methods for the pathology assessment of preclinical studies evaluating the safety and/or efficacy of cardiac ablation catheter systems as well as discuss correlation of pathology data with other supporting evidence for safety and efficacy such as acute, electroanatomical data.

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