scholarly journals The Clinical Sequencing Evidence-Generating Research Consortium: Integrating Genomic Sequencing in Diverse and Medically Underserved Populations

2018 ◽  
Vol 103 (3) ◽  
pp. 319-327 ◽  
Author(s):  
Laura M. Amendola ◽  
Jonathan S. Berg ◽  
Carol R. Horowitz ◽  
Frank Angelo ◽  
Jeannette T. Bensen ◽  
...  
2020 ◽  
Vol 37 (1) ◽  
pp. 231-234 ◽  
Author(s):  
Tasha Woodall ◽  
Melinda Ramage ◽  
John T. LaBruyere ◽  
William McLean ◽  
Casey R. Tak

2020 ◽  
Author(s):  
Stephanie Ioannou ◽  
Kyle Sutherland ◽  
Daniel A. Sussman ◽  
Amar R. Deshpande

Abstract Adherence to colorectal cancer screening is suboptimal, particularly in medically underserved populations. We report here on our assessment of the impact of offering a blood-based screening test on screening rates in a health fair setting. Patients attending student-run health fairs who met colon cancer screening guideline eligibility criteria received a recommendation to attend that screening station. Patients were offered recommended accepted screening methods, and if they declined they were offered blood-based testing. Screening rates, test outcomes, and the rate of follow up completion of colonoscopy were measured and compared with historic screening outcomes. Of 1401 screening eligible patients, 640 (45.7%) attended the colon cancer screening station, of whom 460 were eligible for assessment. Amongst these, none selected colonoscopy, 30 (6.5%) selected FIT, and 430 (93.5%) selected blood-based testing. Only 2 patients returned the FIT. For the blood test, 88 were positive, and 20 of these received a follow up colonoscopy. Based on this assessment, blood-based testing is an effective method to increase screening rates in medically underserved populations, though efforts to further improve access to follow up colonoscopy are necessary.


2018 ◽  
Vol 218 (1) ◽  
pp. S562
Author(s):  
Joshua I. Rosenbloom ◽  
D. Michael Nelson ◽  
Scott Saunders ◽  
F. Sessions Cole ◽  
George A. Macones ◽  
...  

2019 ◽  
Vol 43 ◽  
pp. 201-207 ◽  
Author(s):  
Dagmara I. Moscoso ◽  
David Goese ◽  
Gregory J. Van Hyfte ◽  
Zelda Mayer ◽  
Loretta Cain ◽  
...  

2021 ◽  
Vol 18 (5) ◽  
pp. 441-454
Author(s):  
Nangel M Lindberg ◽  
Amanda M Gutierrez ◽  
Kathleen F Mittendorf ◽  
Michelle A Ramos ◽  
Beatriz Anguiano ◽  
...  

Aim: To increase Spanish speakers' representation in genomics research, accessible study materials on genetic topics must be made available in Spanish. Materials & methods: The Clinical Sequencing Evidence-Generating Research consortium is evaluating genome sequencing for underserved populations. All sites needed Spanish translation of recruitment materials, surveys and return of results. Results: We describe our process for translating site-specific materials, as well as shared measures across sites, to inform future efforts to engage Spanish speakers in research. Conclusion: In translating and adapting study materials for roughly 1000 Spanish speakers across the USA, and harmonizing translated measures across diverse sites, we overcame numerous challenges. Translation should be performed by professionals. Studies must allocate sufficient time, effort and budget to translate and adapt participant materials.


2021 ◽  
Vol 111 (8) ◽  
pp. 1409-1412
Author(s):  
Martha P. Montgomery ◽  
Maribeth Eckert ◽  
Megan G. Hofmeister ◽  
Monique A. Foster ◽  
Mark K. Weng ◽  
...  

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