Host response after reconstruction of abdominal wall defects with porcine dermal collagen in a rat model

2004 ◽  
Vol 191 (6) ◽  
pp. 1961-1970 ◽  
Author(s):  
Fang Zheng ◽  
Yuan Lin ◽  
Eric Verbeken ◽  
Filip Claerhout ◽  
Maxime Fastrez ◽  
...  
2010 ◽  
Vol 76 (1) ◽  
pp. 96-100 ◽  
Author(s):  
Luis Felipe Chavarriaga ◽  
Edward Lin ◽  
Albert Losken ◽  
Michael W. Cook ◽  
Louis O. Jeansonne ◽  
...  

Multiple techniques have been used for the repair of complex abdominal wall defects after recurrent incisional hernias with varying rates of success. Primary repair has been associated with high recurrence rates, and prosthetic mesh placement is contraindicated in contaminated surgical fields. The development of biologic prostheses has changed the approach to these difficult problems. This study evaluates the management of complex abdominal wall defects using acellular porcine dermal collagen. Between August 2006 and May 2007, 18 patients underwent abdominal wall reconstruction for complex defects with acellular porcine dermal collagen (CollaMend™; Bard Inc., Warwick, RI). Patient demographics, preoperative risk factors, previous herniorrhaphy attempts, postoperative complications, recurrences, and long-term results were retrospectively reviewed. Records were reviewed at a mean follow up of 7.3 months; the recurrence rate was 44.4 per cent. A total of 38.9 per cent (seven of 18) developed a postoperative wound complications, including infection in 22.2 per cent (four of 18). All of the patients with infection required prosthesis removal as a result of encapsulation rather than incorporation of the biologic prosthesis. Acellular porcine dermal collagen has the potential for reconstruction of abdominal wall defects with postoperative wound occurrences comparable with other biologic materials. Encapsulation of the material was a major problem in cases with wound infection that required graft removal rather than local wound measures. Hernia recurrence and dehiscence of the graft were problems in noncompromised surgical fields.


2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Idit Melnik ◽  
Youri Mnouskin ◽  
Edna Verdiger Kurzbart ◽  
Boris Yoffe

The presence of a contaminated surgical field in abdominal wall defects caused by trauma presents a challenge for surgeons. Both primary suture and synthetic meshes are strongly discouraged as surgical treatments in such cases. We describe the use of a porcine dermal collagen (Permacol) implant in an eight-year-old patient with multiple injuries. Three months after discharge, the child remains well with good cosmetic results. He is free of pain and has returned to full activity levels with complete wound closure and without any evidence of residual hernia. In conclusion, our experience indicates that the use of Permacol can be considered an efficient technique for reconstructing an infected abdominal wall defect of a pediatric multitrauma patient.


2006 ◽  
Vol 392 (4) ◽  
pp. 473-478 ◽  
Author(s):  
R. Ott ◽  
T. Hartwig ◽  
A. Tannapfel ◽  
R. Blatz ◽  
A. C. Rodloff ◽  
...  

2006 ◽  
Vol 63 (4) ◽  
pp. 255-258 ◽  
Author(s):  
David M. Parker ◽  
Peter J. Armstrong ◽  
James D. Frizzi ◽  
James H. North

2007 ◽  
Vol 31 (10) ◽  
pp. 1966-1972 ◽  
Author(s):  
Faisal M. Shaikh ◽  
Subhasis K. Giri ◽  
Shaukat Durrani ◽  
David Waldron ◽  
Pierce A. Grace

2013 ◽  
Vol 77 (S2) ◽  
pp. 407-411 ◽  
Author(s):  
Murat Kalin ◽  
Serdar Kuru ◽  
Kemal Kismet ◽  
Aziz Mutlu Barlas ◽  
Yusuf Akif Akgun ◽  
...  

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