Time interval from late preterm antenatal corticosteroid administration to delivery and the impact on neonatal outcomes

Author(s):  
Moti GULERSEN ◽  
Cynthia GYAMFI-BANNERMAN ◽  
Michelle GREENMAN ◽  
Erez LENCHNER ◽  
Burton ROCHELSON ◽  
...  
2021 ◽  
Vol 224 (2) ◽  
pp. S594-S595
Author(s):  
Moti Gulersen ◽  
Cynthia Gyamfi-Bannerman ◽  
Michelle Greenman ◽  
Erez Lenchner ◽  
Burton Rochelson ◽  
...  

2011 ◽  
Vol 205 (1) ◽  
pp. 49.e1-49.e7 ◽  
Author(s):  
Femke F. Wilms ◽  
Jolande Y. Vis ◽  
Desiree A.P.M. Pattinaja ◽  
Rosanna A. Kuin ◽  
Monique C. Stam ◽  
...  

2018 ◽  
Vol 33 (12) ◽  
pp. 2109-2115
Author(s):  
Joshua I. Rosenbloom ◽  
Adam K. Lewkowitz ◽  
Kristina E. Sondgeroth ◽  
Jessica L. Hudson ◽  
George A. Macones ◽  
...  

2021 ◽  
Author(s):  
Yoav Siegler ◽  
Naphtali Justman ◽  
Gal Bachar ◽  
Roy Lauterbach ◽  
Yaniv Zipori ◽  
...  

Abstract Objective We assessed the association between a short Antenatal Corticosteroid Administration-to-Birth Interval and neonatal outcome. Study design: A retrospective study between 2010- 2020. Eligible cases were singleton preterm live-born neonates born between 24 0/7 and 33 6/7 weeks of gestation and were initiated an ACS course of Betamethasone. We divided the first 48 hours following 1st ACS administration to four-time intervals and compared each time interval to those born more than 48 hours following ACS administration. The primary outcome was a composite of adverse neonatal outcome, including neonatal mortality or any major neonatal morbidity. Results A total of 200 women gave birth less than 48 hours from receiving the first betamethasone injection, and 172 women gave birth within 2-7 days (48-168 hours) from ACS administration. Composite adverse neonatal outcome was higher for neonates born less than 12 hours from initial ACS administration compared to neonates born 2-7 days from first betamethasone injection (55.45% vs. 29.07%, OR 3.45 95% CI [2.02-5.89], p.value<0.0001). However, there was no difference in composite adverse neonatal outcomes between neonates born 12-48 hours following ACS administration and those born after 2-7 days. That was also true after adjusting for confounders. Conclusions 12-24 hours following ACS Administration may be sufficient in reducing the same risk of neonatal morbidities as > 48 hours following ACS administration. It may raise the question regarding the utility of the second dose of ACS.


2016 ◽  
Vol 214 (1) ◽  
pp. S448
Author(s):  
Catherine Igel ◽  
Nicole Neto ◽  
Diana Wolfe ◽  
Pe'er Dar ◽  
Ashlesha Dayal ◽  
...  

2007 ◽  
Vol 196 (5) ◽  
pp. 457.e1-457.e6 ◽  
Author(s):  
Allison M. Ring ◽  
Jeffery S. Garland ◽  
Brian R. Stafeil ◽  
Margaret H. Carr ◽  
Gail S. Peckman ◽  
...  

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