Serum BDNF levels, glycolipid metabolism in deficit schizophrenia: a case-control study

2022 ◽  
pp. 103003
Author(s):  
Xu Zhu ◽  
Dachun Chen ◽  
Meihong Xiu ◽  
Shen Li ◽  
Xiang Yang Zhang
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Glycolipid Metabolism ◽  
Deficit Schizophrenia ◽  
Control Study ◽  
Serum Bdnf

scholarly journals Reduced serum BDNF levels are associated with the increased risk for developing MDD: a case–control study with or without antidepressant therapy

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Md. Prova Zaman Emon ◽  
Rajesh Das ◽  
Nuruna Lovely Nishuty ◽  
M. M. A. Shalahuddin Qusar ◽  
Mohiuddin Ahmed Bhuiyan ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Antidepressant Therapy ◽  
Increased Risk ◽  
Control Study ◽  
Serum Bdnf

scholarly journals Serum BDNF levels before and after the development of mood disorders: a case–control study in a population cohort

2016 ◽  
Vol 6 (4) ◽  
pp. e782-e782 ◽  
Author(s):  
K Ihara ◽  
H Yoshida ◽  
P B Jones ◽  
M Hashizume ◽  
Y Suzuki ◽  
...  
Keyword(s):  
Mood Disorders ◽  
Case Control Study ◽  
Case Control ◽  
Population Cohort ◽  
Before And After ◽  
Control Study ◽  
Serum Bdnf

Serum BDNF levels in patients with opioid dependence during the early withdrawal period: A case control study

2018 ◽  
Vol 681 ◽  
pp. 100-104 ◽  
Author(s):  
Siddharth Sarkar ◽  
Raka Jain ◽  
Shanti M. Kethawath ◽  
Rishi Gupta ◽  
Mukesh Kumar
Keyword(s):  
Opioid Dependence ◽  
Case Control Study ◽  
Case Control ◽  
Withdrawal Period ◽  
Early Withdrawal ◽  
Control Study ◽  
Serum Bdnf

scholarly journals Serum BDNF and suicidal ideation in drug-naïve and drug-treated MDD patients: a case–control study

2021 ◽  
Vol 57 (1) ◽  
Author(s):  
Amira Mohamed Yousef ◽  
Ghada Mohamed Salah El-Deen ◽  
Abdallah Saad Ibrahim ◽  
Amany Elshabrawy Mohamed
Keyword(s):  
Synaptic Plasticity ◽  
Suicidal Ideation ◽  
Disease Duration ◽  
Case Control Study ◽  
Case Control ◽  
The Other ◽  
Other Hand ◽  
Drug Naïve ◽  
Control Study ◽  
Serum Bdnf

Abstract Background Disturbances in structural and synaptic plasticity have been linked to depression and suicidal ideation. One of the major neurotrophic factors, the brain-derived neurotrophic factor (BDNF), is involved in the maintenance and survival of neurons and synaptic plasticity. This case–control study assesses the serum BDNF and suicidal ideation among drug-naïve and drug-treated MDD patients attending university hospitals and comparing them to healthy control. A simple random sample of 57 MDD patients and 57 age- and sex-comparable controls were enrolled. The researchers conducted a semi-structured interview to collect the demographic characteristics and disease history. Structured Clinical Interview for DSM-5 (SCID-5), Hamilton Depression Rating Scale (HDRS), and Beck Scale for Suicidal Ideation (BSS) were applied to the participants. Blood samples were collected to measure plasma BDNF level. Results The MDD group had lower BDNF than the control group. Within the MDD group, drug-naïve patients had significantly lower BDNF than drug-treated patients. Female patients had lower BDNF than male patients. Positive family history of MDD was associated with low BDNF. Severe and moderate cases had lower BDNF than mild cases. High BSS (≥24) was associated with low BDNF. A statistically significant positive correlation was found between BDNF and age, disease duration, duration of the current episode, and the number of previous episodes. On the other hand, a statistically significant negative correlation was found between BDNF and age of MDD onset, HDRS, and BSS. A regression model was highly statistically significant in the prediction of HDRS. BDNF and disease duration were negatively correlated with HDRS. On the other hand, depression treatment status was not significantly associated with the HDRS prediction model. Conclusion Our findings extend the neurotrophic concept of depression by identifying the decreased BDNF levels as a peripheral biomarker of MDD. Our assessment of depression and suicidal ideation (SI) and their relationship to decreased BDNF levels shed light on the etiopathology of MDD and its related suicidality. They should be more studied to understand better the mechanisms by which they develop. To further explore the effect of BDNF in suicide, larger study sizes and a range of psychiatric diagnoses associated with suicide attempts are required.

Long-term out come in patients undergoing liver transplantation (OLT) for cryptogenic cimhosis (CC): A case control study

2001 ◽  
Vol 120 (5) ◽  
pp. A372-A372
Author(s):  
S KHAN ◽  
J EASON ◽  
G LOSS ◽  
A MASON ◽  
S NAIR
Keyword(s):  
Liver Transplantation ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

Outcome of jejunoileal Crohn's disease: A case-control study

2001 ◽  
Vol 120 (5) ◽  
pp. A282-A282
Author(s):  
T HIGUERO ◽  
C MERLE
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

Precursor lesions of gastric polyps developing during maintenance omeprazole. A case-control study

2001 ◽  
Vol 120 (5) ◽  
pp. A657-A658
Author(s):  
A CATS ◽  
E BLOEMENA ◽  
E SCHENK ◽  
I CLINICS ◽  
S MEUWISSEN ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Precursor Lesions ◽  
Gastric Polyps ◽  
Control Study

Risk factors for esophageal adenocarcinoma: A case-control study

2001 ◽  
Vol 120 (5) ◽  
pp. A442-A442
Author(s):  
B AVIDAN ◽  
A SONNENBERG ◽  
T SCHNELL ◽  
G CHEJFEC ◽  
A METZ ◽  
...  
Keyword(s):  
Risk Factors ◽  
Esophageal Adenocarcinoma ◽  
Case Control Study ◽  
Case Control ◽  
Control Study
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