scholarly journals Ethanol-paired stimuli can increase reinforced ethanol responding

Alcohol ◽  
2020 ◽  
Vol 85 ◽  
pp. 27-34
Author(s):  
R.J. Lamb ◽  
Charles W. Schindler ◽  
Brett C. Ginsburg
Keyword(s):  
1979 ◽  
Vol 10 (3) ◽  
pp. 139-144
Author(s):  
Cheri L. Florance ◽  
Judith O’Keefe

A modification of the Paired-Stimuli Parent Program (Florance, 1977) was adapted for the treatment of articulatory errors of visually handicapped children. Blind high school students served as clinical aides. A discussion of treatment methodology, and the results of administrating the program to 32 children, including a two-year follow-up evaluation to measure permanence of behavior change, is presented.


1979 ◽  
Vol 22 (2) ◽  
pp. 236-246 ◽  
Author(s):  
Jeffrey L. Danhauer ◽  
Ruth M. Lawarre

Perceptual patterns in rating dissimilarities among 24 CVs were investigated for a group of normal-hearing and two groups of hearing-impaired subjects (one group with flat, and one group with sloping, sensorineural losses). Stimuli were presented binaurally at most comfortable loudness level and subjects rated the 576 paired stimuli on a 1–7 equal-appearing interval scale. Ratings were submitted to individual group and combined INDSCAL analyses to describe features used by the subjects in their perception of the speech stimuli. Results revealed features such as sibilant, sonorant, plosive and place. Furthermore, normal and hearing-impaired subjects used similar features, and subjects' weightings of features were relatively independent of their audiometric configurations. Results are compared to those of previous studies.


Cephalalgia ◽  
2017 ◽  
Vol 38 (4) ◽  
pp. 744-753 ◽  
Author(s):  
Fu-Jung Hsiao ◽  
Shuu-Jiun Wang ◽  
Yung-Yang Lin ◽  
Jong-Ling Fuh ◽  
Yu-Chieh Ko ◽  
...  

Background Brain excitability is changed in migraine but not fully characterized yet. This study explored if somatosensory gating is altered in migraine and linked to migraine chronification. Methods Paired electrical stimuli were delivered to the left index fingers of 21 patients with migraine without aura (MO), 22 patients with chronic migraine (CM), and 36 controls. The first and second responses to the paired stimuli were obtained from the contralateral primary (cSI), contralateral secondary (cSII) and ipsilateral secondary (iSII) somatosensory cortices to compute the gating ratios (second vs. first response strengths). Results The first and second cSI responses and gating ratios differed in all groups ( p < 0.05); the responses were typically smaller in the MO and CM groups. The cSI gating ratio increased as a continuum across controls (0.73 ± 0.04, p < 0.001), MO (0.83 ± 0.04) to CM (0.97 ± 0.06) and was higher in CM vs. controls ( p < 0.001). When MO and CM were combined, cSI gating ratio was associated with headache frequency (r = 0.418, p = 0.005). Paired responses and gating ratios of cSII and iSII did not differ among the groups. Conclusions Somatosensory gating is altered in migraine and associated with headache chronification. Further studies must clarify if this abnormal sensory modulation is a true gating deficit independent of low preexcitation level.


2021 ◽  
Vol 224 (3) ◽  
pp. jeb238444
Author(s):  
Kaylyn A. S. Flanigan ◽  
Daniel D. Wiegmann ◽  
Eileen A. Hebets ◽  
Verner P. Bingman

ABSTRACTWhip spiders (Amblypygi) reside in structurally complex habitats and are nocturnally active yet display notable navigational abilities. From the theory that uncertainty in sensory inputs should promote multisensory representations to guide behavior, we hypothesized that their navigation is supported by a multisensory and perhaps configural representation of navigational inputs, an ability documented in a few insects and never reported in arachnids. We trained Phrynus marginemaculatus to recognize a home shelter characterized by both discriminative olfactory and tactile stimuli. In tests, subjects readily discriminated between shelters based on the paired stimuli. However, subjects failed to recognize the shelter in tests with either of the component stimuli alone. This result is consistent with the hypothesis that the terminal phase of their navigational behavior, shelter recognition, can be supported by the integration of multisensory stimuli as an enduring, configural representation. We hypothesize that multisensory learning occurs in the whip spiders' extraordinarily large mushroom bodies, which may functionally resemble the hippocampus of vertebrates.


2020 ◽  
Vol 114 (3) ◽  
pp. 198-211
Author(s):  
Wataru Toyoda ◽  
Ryo Miyamoto ◽  
Susumu Oouchi ◽  
Takenobu Inoue

Introduction: The purpose of this study was to determine the discriminable height differences of raised lines printed on paper, as assessed by people who are blind, with or without years of tactile experience. Methods: Ten younger and 10 older tactile readers with blindness and with rich tactile experience; and 10 blindfolded, older, sighted participants with little tactile experience discriminated paired raised-line stimuli of different heights using the fingers of their preferred hand by active touch in a psychophysical experiment. Results: There was a significant main effect of the height of the stimulus, F(2, 54) = 56.446, MS = .060, p < .001, [Formula: see text] = .676, [Formula: see text] = .341, and participant group, F(2, 27) = 13.717, MS = .064, p < .001, [Formula: see text] = .504, [Formula: see text] = .357; however, there was no significant main effect of the width of the lines, or any interactions. The younger and older tactile readers had virtually similar thresholds and Weber fractions, and they could discriminate paired stimuli more accurately and efficiently than the older, sighted participants. We provided the discriminable height data of the raised lines based on the mean and 95th percentile values of the Weber fractions. Discussion: The results indicate the importance of tactile experiences for height discrimination in active touch. For older persons with recently developed blindness, raised lines with larger height differences should be used. Information for practitioners: These data will be helpful for developing new braille embossers that can print raised-line graphics for people with visual impairments, with or without years of tactile experience.


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