scholarly journals Correlation between ER, PR, HER-2, and Ki-67 with the risk of bone metastases detected by bone scintigraphy in breast cancer patients: A cross sectional study

2021 ◽  
pp. 102532
Author(s):  
Hanif Afkari ◽  
Firdian Makrufardi ◽  
Basuki Hidayat ◽  
Hendra Budiawan ◽  
Achmad Hussein Sundawa Kartamihardja
2021 ◽  
pp. 107815522110391
Author(s):  
Sujana H Chowdhury ◽  
Bilkis Banu ◽  
Nasrin Akter ◽  
Sarder M Hossain

Background Breast cancer survivor goes through a period of needs in their post-treatment daily life. Relatively few studies have been conducted to understand the unmet needs among breast cancer survivors in Bangladesh. Recognize and measure patterns and predictors of unmet needs of breast cancer patients was the aim of the study. Objective To identify and measure patterns and predictors of unmet needs of breast cancer patients in Bangladesh. Method A cross-sectional study among 138 breast cancer patients; conveniently selected from two public and two private cancer institutes. Face-to-face interview for data collection and medical record review for checklist was done. Unmet needs have been determined by the supportive care needs survey short form 34 scale. Logistic regression analyses were performed to identify the predictors of unmet needs. Results The study indicated the top 10 moderate-to-high needs; among which the top five needs were from the information need domain. Surprisingly, private cancer treatment centers were identified as a significant predictor for unmet needs. Patients from private cancer institutes reported more explanation needs as well as needs with their physical and daily living and sexuality. Furthermore, the type of treatment like patient receiving combine treatment therapy reported more need for help compared to the patient receiving chemotherapy alone. Moreover, housewives reported the low need for patient care and support systems as a result of their reluctant behavior towards their health. Conclusion Individual’s unmet need assessment should be a part of every treatment protocol of breast cancer for a better treatment outcome.


2008 ◽  
Vol 26 (15_suppl) ◽  
pp. 22160-22160
Author(s):  
N. Raizada ◽  
H. S. Vadiraja ◽  
R. M. Raghavendra ◽  
B. S. Ajaikumar ◽  
R. S. Bilimagga ◽  
...  

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e18132-e18132
Author(s):  
Elna Kuehnle ◽  
Wulf Siggelkow ◽  
Iris Schrader ◽  
Kristina Luebbe ◽  
Stefanie Noeding ◽  
...  

e18132 Background: In 2003 the German Cancer Society and the German Society for Breast Disease introduced a number of Quality Indicators (QIs) to improve standards of breast cancer care. Although QIs should be based on clinical evidence, evidence for important subpopulations (i.e. vulnerable patients) is often limited. In this prospective cross-sectional study we assessed conformity and non-conformity of guidelines and their impact on clinical outcome in a real-world setting. Methods: This prospective analysis included patients with primary breast cancer. Patients with stage IV and recurrent breast cancer were excluded. Data was collected from 2012-2016 in six certified breast care centers using a personal questionnaire and data from the patients' medical records. Guideline adherence to a set of 11 QIs was explored. Overall survival (OS) and disease free survival (DFS) were correlated with fulfillment of QIs and tumor characteristics. Results: Survival analysis was conducted in 2390 patients with a median follow-up of 16 months. 88 (4%) patients had a recurrent disease. 31 (1.3%) patients died of breast cancer. Tumor stage, grading, Her2- and hormone receptor status and Ki-67 correlated with DFS and OS. 1725/1907 patients (90.5%) received a guideline adherent treatment. The most prevalent reasons for non-conformity were old age (24.7%) and/or comorbidity (20.9%). Breast cancer specific DFS and OS were not significantly different between patients treated adherent or not adherent to the guidelines. In contrast, survival analysis of death other than breast cancer showed a significantly worse OS (p = 0.006) for patients not treated according to guideline recommendation. Conclusions: Conformity of clinical guidelines was observed in the majority of patients including healthy and vulnerable patients. These patients tended to have a longer breast cancer specific survival. Patients who were not considered suitable for guideline-adherent therapy died more often from other medical reasons rather than from breast cancer. In our study 10% of the patients had a limited life expectancy due to old age and co-morbidities with no assumed benefit from guideline adherence.


The Breast ◽  
2017 ◽  
Vol 31 ◽  
pp. 26-33 ◽  
Author(s):  
Soufiane Berhili ◽  
Selma Kadiri ◽  
Amal Bouziane ◽  
Abdallah Aissa ◽  
Elamin Marnouche ◽  
...  

2017 ◽  
Vol 33 (3) ◽  
pp. 602-609
Author(s):  
Mehtap Kartal ◽  
Nilgun Ozcakar ◽  
Sehnaz Hatipoglu ◽  
Makbule Neslisah Tan ◽  
Azize Dilek Guldal

2020 ◽  
Author(s):  
Tamrat Alem ◽  
Dabere Nigatu ◽  
Amsalu Birara ◽  
Tamene Fetene ◽  
Mastewal Giza

Abstract BackgroundAlthough breast cancer has a markedly higher incidence in developed countries, 50% of the new diagnosis and 70% of deaths occur in developing countries. There are limited data available on the quality of life among breast cancer patients in Ethiopia, notably in the Amhara region. This study aimed to assess the quality of life and associated factors among patients with breast cancer in the Amhara Region, Ethiopia, 2019.MethodsInstitutional based cross-sectional study was conducted from March 25 to July 7/2019 among 256 patients with breast cancer in the Amhara region. A systematic random sampling technique was used. Data were collected by using a standardized interviewer-administered Amharic version of the European Organization for research and treatment of cancer quality of life questionnaire core 30(EORTC QLQ C30) and breast cancer supplementary measure (QLQ-BR23). Data were analyzed by SPSS version 23. A binary logistic regression model was fitted to identify the associated factors. The odds ratio (OR) with 95% confidence interval (CI) was used to measure the strength of association.ResultsSixty-eight point four percent (68.4%) of breast cancer patient's QoL was poor. The mean score of quality of life was 70.6(standard deviation (SD) ±13.9; 95% CI: 69.0-72.4). All functional component scores were less than 75, from the symptom scale; diarrhea (11.6), constipation (17.5), and dyspnea (24.7) were less noticeable. Unmarried patients (AOR=2.59, 95% CI: 1.32-5.07), poor (AOR=2.39, 95%CI: 1.32-5.03), non housewife (AOR=3.25, 95% CI: 1.16-7.22), and complaints to dyspnea (AOR=3.48, 95% CI: 1.79-6.79), and insomnia (AOR=2.03, 95% CI: 1.05-3.91) were significantly associated with quality of life.ConclusionsHealth care professionals should give attention to unmarried, and non-housewife breast cancer patients, besides the treatment to improve the health of breast cancer patients.


2021 ◽  
Vol 6 (3) ◽  
pp. 297-303
Author(s):  
Rashmi Mulmi ◽  
Gambhir Shrestha ◽  
Surya Raj Niraula ◽  
Deepak Kumar Yadav ◽  
Paras Kumar Pokharel

Objective: Family history is a significant risk factor for development of breast cancer, particularly for women of first-degree relatives. For women at high risk for breast cancer, regular screening is the mainstay of risk management. This study aims to find out the breast cancer screening practices among first degree relatives of breast cancer patient. Methods: A cross-sectional study was carried out among 150 purposively selected first-degree female relatives of breast cancer patients undergoing treatment at B.P Koirala Memorial Cancer Hospital, aged between 20 and 60 years. A semi-structured questionnaire was used to collect data by face to face interview, which included socio-demographic characteristics, personal history, awareness on breast cancer and screening practices. Results: The mean age of the participants was 37.6 years (SD 10.9). A total of 116 (77.3%) women had ever practiced breast self-examination (regular=34.7%; irregular= 42.7%) and 42 (28.0%) had ever practiced clinical breast examination (regular=14.7%; irregular=13.3%). Only 10 percent of the women had performed mammogram regularly. Only two-fifth of them had a high level of awareness on risk factors and warning signs of breast cancer. Conclusions: This study showed a low rate of regular screening practices among the first degree relatives of breast cancer patients. There is a need to provide comprehensive, and inclusive information and support and interventions aimed at increasing awareness of the importance of healthy behaviors in cancer prevention among these high-risk groups.


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