2-((1H-indol-3-yl)thio)-N-phenyl-acetamides: SARS-CoV-2 RNA-dependent RNA polymerase inhibitors

2019 ◽

Vol 54 (4) ◽

pp. 502-506 ◽

Cited By ~ 5

Author(s):

Yuan Lin ◽

Hongjuan Zhang ◽

Weibao Song ◽

Shuyi Si ◽

Yanxing Han ◽

...

Keyword(s):

Rna Polymerase ◽

Zika Virus ◽

Rna Dependent Rna Polymerase ◽

Polymerase Inhibitors ◽

Identification And Characterization

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HCV NS5b RNA-Dependent RNA Polymerase Inhibitors: From α,γ-Diketoacids to 4,5-Dihydroxypyrimidine- or 3-Methyl-5- hydroxypyrimidinonecarboxylic Acids. Design and Synthesis

Journal of Medicinal Chemistry ◽

10.1021/jm0494669 ◽

2004 ◽

Vol 47 (22) ◽

pp. 5336-5339 ◽

Cited By ~ 73

Author(s):

Vincenzo Summa ◽

Alessia Petrocchi ◽

Victor G. Matassa ◽

Marina Taliani ◽

Ralph Laufer ◽

...

Keyword(s):

Rna Polymerase ◽

Rna Dependent Rna Polymerase ◽

Design And Synthesis ◽

Polymerase Inhibitors ◽

Hcv Ns5b

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Phenyldihydroxypyrimidines as HCV NS5B RNA Dependent RNA Polymerase Inhibitors. Part II: Sulfonamides

Letters in Drug Design & Discovery ◽

10.2174/1570180054771527 ◽

2005 ◽

Vol 2 (6) ◽

pp. 456-461 ◽

Cited By ~ 1

Author(s):

S. Ponzi ◽

C. Giuliano ◽

M. Donghi ◽

M. Poma ◽

V. Matassa ◽

...

Keyword(s):

Rna Polymerase ◽

Rna Dependent Rna Polymerase ◽

Polymerase Inhibitors ◽

Hcv Ns5b

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Diastereoselective 1,3-Dipolar Cycloaddition Reactions between Azomethine Ylides and Chiral Acrylates Derived from Methyl (S)- and (R)-Lactate – Synthesis of Hepatitis C Virus RNA-Dependent RNA Polymerase Inhibitors

European Journal of Organic Chemistry ◽

10.1002/ejoc.200700267 ◽

2007 ◽

Vol 2007 (30) ◽

pp. 5038-5049 ◽

Cited By ~ 30

Author(s):

Carmen Nájera ◽

M. de Gracia Retamosa ◽

José M. Sansano ◽

Abel de Cózar ◽

Fernando P. Cossío

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Rna Polymerase ◽

Azomethine Ylides ◽

Dipolar Cycloaddition ◽

Cycloaddition Reactions ◽

Hepatitis C Virus Rna ◽

Rna Dependent Rna Polymerase ◽

Polymerase Inhibitors ◽

Virus Rna

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Structure–activity relationship (SAR) studies of quinoxalines as novel HCV NS5B RNA-dependent RNA polymerase inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2006.12.103 ◽

2007 ◽

Vol 17 (6) ◽

pp. 1663-1666 ◽

Cited By ~ 75

Author(s):

Frank Rong ◽

Suetying Chow ◽

Shunqi Yan ◽

Gary Larson ◽

Zhi Hong ◽

...

Keyword(s):

Rna Polymerase ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Rna Dependent Rna Polymerase ◽

Sar Studies ◽

Polymerase Inhibitors ◽

Structure Activity ◽

Hcv Ns5b

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Natural RNA dependent RNA polymerase inhibitors: Molecular docking studies of some biologically active alkaloids of Argemone mexicana

Medical Hypotheses ◽

10.1016/j.mehy.2020.109905 ◽

2020 ◽

Vol 144 ◽

pp. 109905 ◽

Cited By ~ 3

Author(s):

K.B. Pandeya ◽

Aditya Ganeshpurkar ◽

Mahendra Kumar Mishra

Keyword(s):

Molecular Docking ◽

Rna Polymerase ◽

Docking Studies ◽

Biologically Active ◽

Rna Dependent Rna Polymerase ◽

Argemone Mexicana ◽

Molecular Docking Studies ◽

Polymerase Inhibitors

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Benzimidazole Derivatives Bearing Substituted Biphenyls as Hepatitis C Virus NS5B RNA-Dependent RNA Polymerase Inhibitors: Structure−Activity Relationship Studies and Identification of a Potent and Highly Selective Inhibitor JTK-109

Journal of Medicinal Chemistry ◽

10.1021/jm060269e ◽

2006 ◽

Vol 49 (15) ◽

pp. 4721-4736 ◽

Cited By ~ 107

Author(s):

Shintaro Hirashima ◽

Takayoshi Suzuki ◽

Tomio Ishida ◽

Satoru Noji ◽

Shinji Yata ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Rna Polymerase ◽

Structure Activity Relationship ◽

Selective Inhibitor ◽

Activity Relationship ◽

Benzimidazole Derivatives ◽

Rna Dependent Rna Polymerase ◽

Polymerase Inhibitors ◽

Structure Activity

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Multiple virtual screening approaches for finding new Hepatitis c virus RNA-dependent RNA polymerase inhibitors: Structure-based screens and molecular dynamics for the pursue of new poly pharmacological inhibitors

BMC Bioinformatics ◽

10.1186/1471-2105-13-s17-s5 ◽

2012 ◽

Vol 13 (S17) ◽

Cited By ~ 20

Author(s):

Mahmoud ElHefnawi ◽

Mohammad ElGamacy ◽

Mohamed Fares

Keyword(s):

Molecular Dynamics ◽

Hepatitis C Virus ◽

Hepatitis C ◽

Virtual Screening ◽

Rna Polymerase ◽

Hepatitis C Virus Rna ◽

Rna Dependent Rna Polymerase ◽

Polymerase Inhibitors ◽

Virus Rna ◽

Screening Approaches

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Purification and Characterization of HCV RNA-dependent RNA Polymerase from Korean Genotype 1b Isolate: Implications for Discovery of HCV Polymerase Inhibitors

Bulletin of the Korean Chemical Society ◽

10.5012/bkcs.2005.26.2.285 ◽

2005 ◽

Vol 26 (2) ◽

pp. 285-291

Keyword(s):

Rna Polymerase ◽

Hcv Rna ◽

Purification And Characterization ◽

Rna Dependent Rna Polymerase ◽

Polymerase Inhibitors ◽

Genotype 1B

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Screening of Severe Acute Respiratory Syndrome Coronavirus 2 RNA-Dependent RNA Polymerase Inhibitors Using Computational Approach

Journal of Computational Biology ◽

10.1089/cmb.2020.0639 ◽

2021 ◽

Author(s):

Poonam Dhankhar ◽

Vikram Dalal ◽

Viney Kumar

Keyword(s):

Severe Acute Respiratory Syndrome ◽

Rna Polymerase ◽

Computational Approach ◽

Rna Dependent Rna Polymerase ◽

Polymerase Inhibitors

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2-((1H-indol-3-yl)thio)-N-phenyl-acetamides: SARS-CoV-2 RNA-dependent RNA polymerase inhibitors

Identification and characterization of Zika virus NS5 RNA-dependent RNA polymerase inhibitors

HCV NS5b RNA-Dependent RNA Polymerase Inhibitors: From α,γ-Diketoacids to 4,5-Dihydroxypyrimidine- or 3-Methyl-5- hydroxypyrimidinonecarboxylic Acids. Design and Synthesis

Phenyldihydroxypyrimidines as HCV NS5B RNA Dependent RNA Polymerase Inhibitors. Part II: Sulfonamides

Diastereoselective 1,3-Dipolar Cycloaddition Reactions between Azomethine Ylides and Chiral Acrylates Derived from Methyl (S)- and (R)-Lactate – Synthesis of Hepatitis C Virus RNA-Dependent RNA Polymerase Inhibitors

Structure–activity relationship (SAR) studies of quinoxalines as novel HCV NS5B RNA-dependent RNA polymerase inhibitors

Natural RNA dependent RNA polymerase inhibitors: Molecular docking studies of some biologically active alkaloids of Argemone mexicana

Benzimidazole Derivatives Bearing Substituted Biphenyls as Hepatitis C Virus NS5B RNA-Dependent RNA Polymerase Inhibitors: Structure−Activity Relationship Studies and Identification of a Potent and Highly Selective Inhibitor JTK-109

Multiple virtual screening approaches for finding new Hepatitis c virus RNA-dependent RNA polymerase inhibitors: Structure-based screens and molecular dynamics for the pursue of new poly pharmacological inhibitors

Purification and Characterization of HCV RNA-dependent RNA Polymerase from Korean Genotype 1b Isolate: Implications for Discovery of HCV Polymerase Inhibitors

Screening of Severe Acute Respiratory Syndrome Coronavirus 2 RNA-Dependent RNA Polymerase Inhibitors Using Computational Approach

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