Pilot Study to Evaluate Autologous, Micro-Fragmented Adipose Tissue as a Treatment For Chronic Shoulder Pain in Wheelchair Users with SCI: A 12-month follow up

2020 ◽  
Vol 101 (11) ◽  
pp. e15
Author(s):  
Nathan Hogaboom ◽  
Gerard Malanga ◽  
Chris Cherian ◽  
Trevor Dyson-Hudson
2019 ◽  
Vol 100 (12) ◽  
pp. e193
Author(s):  
Nathan Hogaboom ◽  
Trevor Dyson-Hudson ◽  
Chris Cherian ◽  
Gerard Malanga

2013 ◽  
Vol 34 (6) ◽  
pp. 1097-1108 ◽  
Author(s):  
Ildikó Katalin Tefner ◽  
Csaba Kovács ◽  
Ramóna Gaál ◽  
András Koroknai ◽  
Remény Horváth ◽  
...  

2004 ◽  
Vol 42 (3sup1) ◽  
pp. 1 ◽  
Author(s):  
Bonita J. Sawatzky ◽  
Gerard P. Slobogean ◽  
Christopher W. Reilly ◽  
Christine T. Chambers ◽  
Adrienne T. Hol

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Sengul Aydin Yoldemir ◽  
Yucel Arman ◽  
Murat Akarsu ◽  
Ozgur Altun ◽  
Mustafa Ozcan ◽  
...  

Abstract Background Endotrophin is one of the extracellular matrix proteins secreted by adipose tissue. In this study, we aimed to investigate the effects of changes in blood glucose levels on serum endotrophin levels secreted by adipose tissue and thus on diabetes. Methods In this prospective pilot study included 78 patients with type 2 diabete (T2D) with hemoglobin A1c level > 9 %. Lifestyle changes were recommended and appropriate medical treatment was initiated to all patients in order to reach the target HbA1c level. Data of anthropometric measurements, urinary albumin creatinine ratio (UACR), serum lipid parameters and endotrophin were collected in patients; all examinations were repeated after 3 months. Analysis was performed using Paired-Samles T test and Spearman tests. Results Of patients, 23 were female (54.8 %) and 19 were male (45.2 %). Mean age was 55.2 years, with mean diabetes age of 8.14 ± 5.35 years. After 3 months follow-up, HbA1c, fasting glucose, C-reactive protein(CRP), UACR and endotrophin levels were observed to clearly reduce. The variation in serum endotrophin levels examined at the start of the study and in the 3rd month was identified to have a positive correlation with the variation in HbA1c and UACR levels (r = 0.342, p = 0.02; r = 0.484, p = 0.001). Multiple linear regression analysis showed percentage variation values (δ)-endotrophin levels were only independently correlated with (δ)-UACR (model r2 = 0.257, p value = 0.00). Conclusions Endotrophin levels decreased significantly with the decrease in HbA1c. Unexpectedly, this reduction in endotrophin levels is closely related to the decrease in UACR, regardless of blood glucose regulation. We think that studies targeting endotrophin will contribute to the diagnosis, treatment and follow-up of diabetic nephropathy in the future.


2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Federico Cristiani ◽  
Maria A. Hernandez

Pulsed radiofrequency of the suprascapular nerve has shown efficacy in adults with chronic shoulder pain, but its use in pediatrics is relatively new. We present a case of a successful use of pulsed radiofrequency to treat refractory chronic shoulder pain in an adolescent patient. Case Report. We present a 53 kg, 14-year-old female, with a medical history of septic arthritis of the left shoulder within the first month of life leading to persisting pain during childhood. She presented with a complaint of progressive pain starting at age 12, refractory to analgesics including opioids and intra-articular injection of local anesthetic and steroids. After pulsed radiofrequency of the suprascapular nerve, significant pain relief and improvement of the range of motion was obtained. These results were maintained at the 1-, 3-, and 6-month follow-up visits with the pain being reported as mild and manageable with nonsteroidal anti-inflammatory drugs. Conclusion. There is limited data today of the use of pulsed radiofrequency for pediatric chronic pain. We successfully used this intervention in a 14-year-old patient with chronic shoulder pain extrapolating from adult experience and as a last resort after all other treatments had failed.


2020 ◽  
Author(s):  
Sengul AYDIN YOLDEMIR ◽  
Yucel Arman ◽  
Murat Akarsu ◽  
Ozgur Altun ◽  
Mustafa Ozcan ◽  
...  

Abstract Background: Endotrophin is one of the extracellular matrix proteins secreted by adipose tissue. In this study, we aimed to investigate the effects of changes in blood glucose levels on serum endotropin levels secreted by adipose tissue and thus on diabetes.Methods: In this prospective pilot study included 78 patients with type 2 diabete(T2D) with hemoglobin A1c level >9%. Data of anthropometric measurements, fractional excretion of UA (FEUA), serum lipid parameters and endotrophin were collected in patients; all examinations were repeated after 3 months. Analysis was performed using Paired-Samles T test and Spearman tests. Results: Of patients, 23 were female (54.8%) and 19 were male (45.2%). Mean age was 55.2 years, with mean diabetes age of 8.14 ± 5.35 years. After 3 months follow-up, HbA1c, fasting glucose, CRP, UACR and endotrophin levels were observed to clearly reduce. The variation in serum endotrophin levels examined at the start of the study and in the 3rd month was identified to have a positive correlation with the variation in HbA1c and UACR levels (r=0.342, p=0.02; r=0.484, p=0.001). Multiple linear regression analysis showed percentage variation values (d) -endotrophin levels were only independently correlated with (d)-UACR (model r2=0.257, P value=0.00).Conclusions: The decrease in HbA1c causes a significant decrease in endotropin levels. Unexpectedly, this reduction in endotrophin levels is closely related to the decrease in UACR, regardless of blood glucose regulation. We think that studies targeting endotrophin will contribute to the diagnosis, treatment and follow-up of diabetic nephropathy in the future.


2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Luís Vieira ◽  
Pedro Pereira ◽  
Bernardo Nunes ◽  
Rui Matos ◽  
António Sousa ◽  
...  

Case. A 61-year-old male presented with chronic shoulder pain resistant to conservative treatment. Imaging identified a nodular lesion in the deltoid muscle, which histology after resection identified as a glomus tumor. After surgery, the patient became asymptomatic and at 4-year follow-up has not shown signs of recurrence. Conclusion. Glomus tumors around the shoulder should be considered when investigating chronic shoulder pain, as they are more common than thought. Despite being elusive, when diagnosed, excellent outcomes may be expected, with surgery resection being curative.


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