Antibiotic-loaded articulating cement spacer in the 2-stage exchange of infected total knee arthroplasty

2004 ◽  
Vol 19 (6) ◽  
pp. 768-774 ◽  
Author(s):  
Sridhar M. Durbhakula ◽  
John Czajka ◽  
Marc D. Fuchs ◽  
Richard L. Uhl
2011 ◽  
Vol 45 (6) ◽  
pp. 535 ◽  
Author(s):  
Parag Garg ◽  
Utpal Bandyopadhyay ◽  
SR Mitra ◽  
Rajeev Ranjan ◽  
Shiv Chouksey ◽  
...  

2011 ◽  
Vol 5 (1) ◽  
pp. 86-91 ◽  
Author(s):  
Niraj V Kalore ◽  
Terence J Gioe ◽  
Jasvinder A Singh

Infection following total knee arthroplasty can be difficult to diagnose and treat. Diagnosis is multifactorial and relies on the clinical picture, radiographs, bone scans, serologic tests, synovial fluid examination, intra-operative culture and histology. Newer techniques including ultrasonication and molecular diagnostic studies are playing an expanded role. Two-stage exchange arthroplasty with antibiotic cement and 4-6 weeks of intravenous antibiotic treatment remains the most successful intervention for infection eradication. There is no consensus on the optimum type of interval antibiotic cement spacer. There is a limited role for irrigation and debridement, direct one-stage exchange, chronic antibiotic suppression and salvage procedures like arthrodesis and amputation. We examine the literature on each of the diagnostic modalities and treatment options in brief and explain their current significance.


Joints ◽  
2018 ◽  
Vol 06 (04) ◽  
pp. 241-245
Author(s):  
Giuseppe Solarino ◽  
Giuseppe Maccagnano ◽  
Michele Saracino ◽  
Biagio Moretti

AbstractOne-stage or two-stage revision total knee arthroplasty (TKA) in periprosthetic joint infections has been at the center of scientific debate for many years. As regards two-stage revision TKA, cement spacers have a good infection control rate with successful results reportable up to 96%, though some studies describe related spacer complications such as stiffness and loss of bone stock. We report a case of a fracture close to the antibiotic-loaded cement spacer in a 74-year-old female patient. Due to the blood tests and high risk of infection, we performed a hybrid external fixator. Six months after the surgery, X-rays did not show signs of fracture consolidation and nonunion was considered as an impending complication; therefore, the decision was made to perform tumor-like total knee arthroplasty. The postoperative evolution was satisfactory and return to daily activity without pain. At the 5-year follow-up, the patient showed a good score of 36-Item Short Form Health Survey and a range of motion from 0 to 90° without pain. The X-rays did not show signs of mobilization, dislocation, recurrence of infection, or other complications.


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