Pseudotumors and High-Grade Aseptic Lymphocyte-Dominated Vasculitis-Associated Lesions Around Total Knee Replacements Identified at Aseptic Revision Surgery: Findings of a Large-Scale Histologic Review

2019 ◽  
Vol 34 (10) ◽  
pp. 2434-2438 ◽  
Author(s):  
Andrew P. Kurmis ◽  
Amir Herman ◽  
Adam R. McIntyre ◽  
Bassam A. Masri ◽  
Donald S. Garbuz
Keyword(s):  
Revision Surgery ◽  
Large Scale ◽  
High Grade ◽  
Total Knee Replacements ◽  
Associated Lesions ◽  
Knee Replacements ◽  
Aseptic Revision ◽  
Total Knee

scholarly journals Assessment of Racial Disparities in the Risks of Septic and Aseptic Revision Total Knee Replacements

2021 ◽  
Vol 4 (7) ◽  
pp. e2117581
Author(s):  
Anne R. Bass ◽  
Huong T. Do ◽  
Bella Mehta ◽  
Stephen Lyman ◽  
Serene Z. Mirza ◽  
...  
Keyword(s):  
Racial Disparities ◽  
Total Knee Replacements ◽  
Knee Replacements ◽  
Aseptic Revision ◽  
Total Knee

scholarly journals Chronic, Active Inflammation in Patients With Failed Total Knee Replacements Undergoing Revision Surgery

2019 ◽  
Vol 37 (11) ◽  
pp. 2316-2324 ◽  
Author(s):  
Hannah L. Paish ◽  
Thomas Edward Baldock ◽  
Colin S. Gillespie ◽  
Alicia del Carpio Pons ◽  
Derek A. Mann ◽  
...  
Keyword(s):  
Revision Surgery ◽  
Total Knee Replacements ◽  
Knee Replacements ◽  
Total Knee ◽  
Active Inflammation

Impact of perivascular lymphocytic infiltration in aseptic total knee revision

2021 ◽  
Vol 103-B (6 Supple A) ◽  
pp. 145-149
Author(s):  
David A. Crawford ◽  
Braden J. Passias ◽  
Joanne B. Adams ◽  
Keith R. Berend ◽  
Adolph V. Lombardi
Keyword(s):  
Clinical Outcomes ◽  
Revision Surgery ◽  
Large Scale ◽  
Histological Analysis ◽  
Lymphocytic Infiltration ◽  
Radiological Data ◽  
Significant Difference ◽  
Outcome Scores ◽  
Aseptic Revision ◽  
Total Knee

Aims A limited number of investigations with conflicting results have described perivascular lymphocytic infiltration (PVLI) in the setting of total knee arthroplasty (TKA). The purpose of this study was to determine if PVLI found in TKAs at the time of aseptic revision surgery was associated with worse clinical outcomes and survivorship. Methods A retrospective review was conducted on 617 patients who underwent aseptic TKA revision who had histological analysis for PVLI at the time of surgery. Clinical and radiological data were obtained pre- and postoperatively, six weeks postoperatively, and then every year thereafter. Results Within this cohort, 118 patients (19.1%) were found to have PVLI on histological analysis. Re-revision was performed on 83 patients (13.4%) with no significant differences in all-cause or aseptic revisions between groups. A higher incidence of PVLI was noted in female patients (p = 0.037). There was no significant difference in improvement in the range of motion (p = 0.536), or improvement of KSC (p = 0.66), KSP (p = 0.61), or KSF (p = 0.3) clinical outcome scores between PVLI and no PVLI sub-groups. There was a higher incidence of a preoperative diagnosis of pain in the PVLI group compared with patients without PVLI (p = 0.002) present. Conclusion PVLI found on large-scale histological analysis in TKAs at aseptic revision surgery was not associated with worse clinical outcomes or rates of re-revision. Cite this article: Bone Joint J 2021;103-B(6 Supple A):145–149.

scholarly journals Towards the understanding of lubrication mechanisms in total knee replacements – Part I: Experimental investigations

2021 ◽  
Vol 156 ◽  
pp. 106874 ◽  
Author(s):  
David Nečas ◽  
Martin Vrbka ◽  
Max Marian ◽  
Benedict Rothammer ◽  
Stephan Tremmel ◽  
...  
Keyword(s):  
Experimental Investigations ◽  
Total Knee Replacements ◽  
Knee Replacements ◽  
Total Knee ◽  
Lubrication Mechanisms

scholarly journals Amorphous Carbon Coatings for Total Knee Replacements—Part I: Deposition, Cytocompatibility, Chemical and Mechanical Properties

Polymers ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 1952
Author(s):  
Benedict Rothammer ◽  
Kevin Neusser ◽  
Max Marian ◽  
Marcel Bartz ◽  
Sebastian Krauß ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Amorphous Carbon ◽  
Detailed Characterization ◽  
Carbon Coatings ◽  
Dlc Coatings ◽  
Total Knee Replacements ◽  
Knee Replacements ◽  
Total Knee ◽  
Amorphous Carbon Coatings

Diamond-like carbon (DLC) coatings have the potential to reduce implant wear and thus to contribute to avoiding premature failure and increase service life of total knee replacements (TKAs). This two-part study addresses the development of such coatings for ultrahigh molecular weight polyethylene (UHMWPE) tibial inlays as well as cobalt–chromium–molybdenum (CoCr) and titanium (Ti64) alloy femoral components. While a detailed characterization of the tribological behavior is the subject of part II, part I focusses on the deposition of pure (a‑C:H) and tungsten-doped hydrogen-containing amorphous carbon coatings (a‑C:H:W) and the detailed characterization of their chemical, cytological, mechanical and adhesion behavior. The coatings are fabricated by physical vapor deposition (PVD) and display typical DLC morphology and composition, as verified by focused ion beam scanning electron microscopy and Raman spectroscopy. Their roughness is higher than that of the plain substrates. Initial screening with contact angle and surface tension as well as in vitro testing by indirect and direct application indicate favorable cytocompatibility. The DLC coatings feature excellent mechanical properties with a substantial enhancement of indentation hardness and elastic modulus ratios. The adhesion of the coatings as determined in modified scratch tests can be considered as sufficient for the use in TKAs.

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