EEG dissociation induced by muscarinic receptor antagonists: Coherent 40 Hz oscillations in a background of slow waves and spindles

2019 ◽  
Vol 359 ◽  
pp. 28-37 ◽  
Author(s):  
Santiago Castro-Zaballa ◽  
Matías Cavelli ◽  
Joaquín González ◽  
Jaime Monti ◽  
Atilio Falconi ◽  
...  
Keyword(s):  
Muscarinic Receptor ◽  
Slow Waves ◽  
Receptor Antagonists ◽  
Muscarinic Receptor Antagonists ◽  
40 Hz

scholarly journals The Impact of Muscarinic Receptor Antagonists on Airway Inflammation: A Systematic Review

2021 ◽  
Vol Volume 16 ◽  
pp. 257-279
Author(s):  
Luigino Calzetta ◽  
Angelo Coppola ◽  
Beatrice Ludovica Ritondo ◽  
Matteo Matino ◽  
Alfredo Chetta ◽  
...  
Keyword(s):  
Systematic Review ◽  
Airway Inflammation ◽  
Muscarinic Receptor ◽  
Receptor Antagonists ◽  
Muscarinic Receptor Antagonists ◽  
The Impact

scholarly journals Novel Potent Muscarinic Receptor Antagonists: Investigation on the Nature of Lipophilic Substituents in the 5- and/or 6-Positions of the 1,4-Dioxane Nucleus

2020 ◽  
Vol 63 (11) ◽  
pp. 5763-5782 ◽  
Author(s):  
Fabio Del Bello ◽  
Alessandro Bonifazi ◽  
Gianfabio Giorgioni ◽  
Alessandro Piergentili ◽  
Maria Giovanna Sabbieti ◽  
...  
Keyword(s):  
Muscarinic Receptor ◽  
Receptor Antagonists ◽  
Muscarinic Receptor Antagonists

scholarly journals Muscarinic Receptor Antagonists, the Overactive Bladder and Efficacy against Urinary Urgency

2010 ◽  
Vol 2 ◽  
pp. CMT.S4606 ◽  
Author(s):  
Kylie J. Mansfield
Keyword(s):  
Overactive Bladder ◽  
Muscarinic Receptor ◽  
Cholinergic System ◽  
Urge Urinary Incontinence ◽  
Urinary Urgency ◽  
Receptor Antagonists ◽  
Antimuscarinic Agents ◽  
Bladder Urothelium ◽  
Afferent Nerves ◽  
Muscarinic Receptor Antagonists

The overactive bladder (OAB) is a debilitating condition in which patients suffer from urinary urgency, frequency and nocturia with or without urge urinary incontinence. The mainstay of pharmacotherapy for OAB is muscarinic receptor antagonists, which have been shown to be effective treatments for the symptoms of OAB. The mechanism underlying the efficacy of antimuscarinic agents against the symptoms of OAB is not completely understood. This review explores the role of bladder mucosal muscarinic receptors in the signaling pathways that are activated in response to bladder filling. The cholinergic system is seen to be involved in bladder afferent signaling at many levels and as such muscarinic receptor antagonists may affect bladder signaling via numerous pathways including release of mediators from the bladder urothelium and activation of suburothelial myofibroblasts and afferent nerves. Therefore the mucosal cholinergic system may represent another target for the antimuscarinic agents used to treat OAB.

Sign in / Sign up

Export Citation Format

Share Document