Hunting oxygen complexes of nitric oxide synthase at low temperature and high pressure

2005 ◽  
Vol 338 (1) ◽  
pp. 529-535 ◽  
Author(s):  
Stéphane Marchal ◽  
Antonius C.F. Gorren ◽  
K. Kristoffer Andersson ◽  
Reinhard Lange
Keyword(s):  
Nitric Oxide ◽  
High Pressure ◽  
Nitric Oxide Synthase ◽  
Low Temperature ◽  
Oxide Synthase ◽  
Oxygen Complexes

scholarly journals Formation of Transient Oxygen Complexes of Cytochrome P450 BM3 and Nitric Oxide Synthase under High Pressure

2003 ◽  
Vol 85 (5) ◽  
pp. 3303-3309 ◽  
Author(s):  
Stéphane Marchal ◽  
Hazel Mary Girvan ◽  
Antonius C.F. Gorren ◽  
Bernd Mayer ◽  
Andrew William Munro ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
High Pressure ◽  
Cytochrome P450 ◽  
Nitric Oxide Synthase ◽  
P450 Bm3 ◽  
Cytochrome P450 Bm3 ◽  
Oxide Synthase ◽  
Oxygen Complexes

Low-Temperature Optical Absorption Spectra Suggest a Redox Role for Tetrahydrobiopterin in Both Steps of Nitric Oxide Synthase Catalysis†

Biochemistry ◽  
2000 ◽  
Vol 39 (38) ◽  
pp. 11763-11770 ◽  
Author(s):  
Antonius C. F. Gorren ◽  
Nicole Bec ◽  
Astrid Schrammel ◽  
Ernst R. Werner ◽  
Reinhard Lange ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Low Temperature ◽  
Optical Absorption ◽  
Absorption Spectra ◽  
Optical Absorption Spectra ◽  
Oxide Synthase

High-pressure studies of the reaction mechanism of nitric-oxide synthase

2006 ◽  
Vol 1764 (3) ◽  
pp. 578-585 ◽  
Author(s):  
Antonius C.F. Gorren ◽  
Stéphane Marchal ◽  
Morten Sørlie ◽  
K. Kristoffer Andersson ◽  
Reinhard Lange ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
High Pressure ◽  
Reaction Mechanism ◽  
Nitric Oxide Synthase ◽  
High Pressure Studies ◽  
Oxide Synthase

scholarly journals Reaction of Neuronal Nitric-oxide Synthase with Oxygen at Low Temperature

1998 ◽  
Vol 273 (22) ◽  
pp. 13502-13508 ◽  
Author(s):  
Nicole Bec ◽  
Antonius C. F. Gorren ◽  
Christof Voelker ◽  
Bernd Mayer ◽  
Reinhard Lange
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Low Temperature ◽  
Neuronal Nitric Oxide Synthase ◽  
Oxide Synthase

Use of high pressure to study elementary steps in P450 and nitric oxide synthase

2001 ◽  
Vol 87 (4) ◽  
pp. 191-195 ◽  
Author(s):  
Reinhard Lange ◽  
Nicole Bec ◽  
Pavel Anzenbacher ◽  
Andrew W Munro ◽  
Antonius C.F Gorren ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
High Pressure ◽  
Nitric Oxide Synthase ◽  
Elementary Steps ◽  
Oxide Synthase

Localization of endothelial nitric oxide synthase in the normal and failing human atrial myocardium

1996 ◽  
Vol 54 ◽  
pp. 786-787
Author(s):  
Chi-Ming Wei ◽  
Margarita Bracamonte ◽  
Shi-Wen Jiang ◽  
Richard C. Daly ◽  
Christopher G.A. McGregor ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Heart Failure ◽  
Nitric Oxide Synthase ◽  
Endothelial Nitric Oxide Synthase ◽  
Cardiac Tissues ◽  
Mammalian Tissues ◽  
End Stage Heart Failure ◽  
End Stage ◽  
Oxide Synthase ◽  
Endothelial Nitric Oxide

Nitric oxide (NO) is a potent endothelium-derived relaxing factor which also may modulate cardiomyocyte inotropism and growth via increasing cGMP. While endothelial nitric oxide synthase (eNOS) isoforms have been detected in non-human mammalian tissues, expression and localization of eNOS in the normal and failing human myocardium are poorly defined. Therefore, the present study was designed to investigate eNOS in human cardiac tissues in the presence and absence of congestive heart failure (CHF).Normal and failing atrial tissue were obtained from six cardiac donors and six end-stage heart failure patients undergoing primary cardiac transplantation. ENOS protein expression and localization was investigated utilizing Western blot analysis and immunohistochemical staining with the polyclonal rabbit antibody to eNOS (Transduction Laboratories, Lexington, Kentucky).

Sign in / Sign up

Export Citation Format

Share Document