Fatty acid binding protein 4 in human skeletal muscle

2006 ◽  
Vol 346 (1) ◽  
pp. 125-130 ◽  
Author(s):  
Heléne Fischer ◽  
Thomas Gustafsson ◽  
Carl Johan Sundberg ◽  
Jessica Norrbom ◽  
Marianne Ekman ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Fatty Acid ◽  
Human Skeletal Muscle ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Acid Binding Protein

scholarly journals Studies of plasma membrane fatty acid-binding protein and other lipid-binding proteins in human skeletal muscle

2004 ◽  
Vol 63 (2) ◽  
pp. 239-244 ◽  
Author(s):  
C. Roepstorff ◽  
J. Wulff Helge ◽  
B. Vistisen ◽  
B. Kiens
Keyword(s):  
Skeletal Muscle ◽  
Fatty Acid ◽  
Exercise Training ◽  
Human Skeletal Muscle ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Membrane Fatty Acid ◽  
Fatty Acid Binding ◽  
Acid Binding Protein ◽  
Long Chain

The first putative fatty acid transporter identified was plasma membrane fatty acid-binding protein (FABPpm). Later it was demonstrated that this protein is identical to the mitochondrial isoform of the enzyme aspartate aminotransferase. In recent years data from several cell types have emerged, indicating that FABPpm plays a role in the transport of long-chain saturated and unsaturated fatty acids. In the limited number of studies in human skeletal muscle it has been demonstrated that dietary composition and exercise training can influence the content of FABPpm. Ingestion of a fat-rich diet induces an increase in FABPpm protein content in human skeletal muscle in contrast to the decrease seen during consumption of a carbohydrate-rich diet. A similar effect of a fat-rich diet is also observed for cytosolic fatty acid-binding protein and fatty acid translocase/CD36 protein expression. Exercise training up regulates FABPpm protein content in skeletal muscle, but only in male subjects; no significant differences were observed in muscle FABPpm content in a cross-sectional study of female volunteers of varying training status, even though muscle FABPpm content did not depend on gender in the untrained state. A higher utilization of plasma long-chain fatty acids during exercise in males compared with females could explain the gender-dependent influence of exercise training on FABPpm. The mechanisms involved in the regulation of the function and expression of FABPpm protein remain to be clarified.

The fatty acid-binding protein from human skeletal muscle

1989 ◽  
Vol 274 (2) ◽  
pp. 556-563 ◽  
Author(s):  
Roger A. Peeters ◽  
Monique A.in't Groen ◽  
Jacques H. Veerkamp
Keyword(s):  
Skeletal Muscle ◽  
Fatty Acid ◽  
Human Skeletal Muscle ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Acid Binding Protein

Fatty Acid Transporters (FABPpm, FAT, FATP) in Human Muscle

1999 ◽  
Vol 24 (6) ◽  
pp. 515-523 ◽  
Author(s):  
Arend Bonen ◽  
Dragana Miskovic ◽  
Bente Kiens
Keyword(s):  
Skeletal Muscle ◽  
Fatty Acid ◽  
Human Skeletal Muscle ◽  
Fatty Acid Binding Protein ◽  
Human Muscle ◽  
Fatty Acid Transport ◽  
Acid Transport ◽  
Fatty Acid Binding ◽  
Acid Binding Protein ◽  
First Time

Recently, a number of putative LCFA transporters have been identified: fatty acid binding protein (FABPpm), fatty acid translocase (FAT/CD36), and fatty acid transport protein (FATP). We have demonstrated, for the first time, that transcripts of all three putative LCFA transporters (FAT mRNA, FATP mRNA, and mAspAT/FABPpm mRNA) are present in human skeletal muscle. Key words: mRNA, membrane

Cloning and tissue distribution of rat heart fatty acid binding protein mRNA: identical forms in heart and skeletal muscle

Biochemistry ◽  
1987 ◽  
Vol 26 (24) ◽  
pp. 7900-7904 ◽  
Author(s):  
Kevin P. Claffey ◽  
Victoria L. Herrera ◽  
Peter Brecher ◽  
Nelson Ruiz-Opazo
Keyword(s):  
Skeletal Muscle ◽  
Fatty Acid ◽  
Tissue Distribution ◽  
Rat Heart ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Acid Binding Protein

Cytoplasmic fatty acid-binding protein facilitates fatty acid utilization by skeletal muscle

2003 ◽  
Vol 178 (4) ◽  
pp. 367-371 ◽  
Author(s):  
J. F. C. Glatz ◽  
F. G. Schaap ◽  
B. Binas ◽  
A. Bonen ◽  
G. J. Van Der Vusse ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Fatty Acid ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Fatty Acid Utilization ◽  
Acid Binding Protein
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