Dipeptidyl peptidase-4 impairs insulin signaling and promotes lipid accumulation in hepatocytes

Kerstin Rufinatscha; Bernhard Radlinger; Jochen Dobner; Sabrina Folie; Claudia Bon; Elisabeth Profanter; Claudia Ress; Karin Salzmann; Gabriele Staudacher; Herbert Tilg; Susanne Kaser

doi:10.1016/j.bbrc.2017.02.071

Dipeptidyl peptidase-4 impairs insulin signaling and promotes lipid accumulation in hepatocytes

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2017.02.071 ◽

2017 ◽

Vol 485 (2) ◽

pp. 366-371 ◽

Cited By ~ 12

Author(s):

Kerstin Rufinatscha ◽

Bernhard Radlinger ◽

Jochen Dobner ◽

Sabrina Folie ◽

Claudia Bon ◽

...

Keyword(s):

Insulin Signaling ◽

Lipid Accumulation ◽

Dipeptidyl Peptidase ◽

Dipeptidyl Peptidase 4

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Sodium acetate improves disrupted glucoregulation and hepatic lipid accumulation in insulin-resistant female rats: involvement of adenosine deaminase and dipeptidyl peptidase-4 activities

Proceedings for Annual Meeting of The Japanese Pharmacological Society ◽

10.1254/jpssuppl.wcp2018.0_po3-6-1 ◽

2018 ◽

Vol WCP2018 (0) ◽

pp. PO3-6-1

Author(s):

Lawrence A. Olatunji ◽

Tolulope E Omolekulo ◽

Olugbenga S Michael

Keyword(s):

Adenosine Deaminase ◽

Lipid Accumulation ◽

Sodium Acetate ◽

Dipeptidyl Peptidase ◽

Female Rats ◽

Hepatic Lipid ◽

Dipeptidyl Peptidase 4 ◽

Insulin Resistant ◽

Hepatic Lipid Accumulation

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Evaluating dipeptidyl peptidase-4 expression in patients with diffuse and focal congenital hyperinsulinism.

Endocrine Abstracts ◽

10.1530/endoabs.36.oc4.6 ◽

2014 ◽

Author(s):

Sofia A Rahman ◽

Maha M A Sherif ◽

Sophia Tahir ◽

Khalid Hussain

Keyword(s):

Dipeptidyl Peptidase ◽

Congenital Hyperinsulinism ◽

Dipeptidyl Peptidase 4

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Soluble dipeptidyl peptidase-4 activity is associated with decreased renal function in patients with type 2 diabetes

Endocrine Abstracts ◽

10.1530/endoabs.56.p421 ◽

2018 ◽

Author(s):

Eun-Hee Cho ◽

Ji Yun Jeong ◽

Mi Young Lee ◽

Jung Min Kim ◽

Mi-Seon Shin

Keyword(s):

Type 2 Diabetes ◽

Renal Function ◽

Dipeptidyl Peptidase ◽

Dipeptidyl Peptidase 4

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Impact of Switching from Sulfonylureas to Dipeptidyl Peptidase-4 Inhibitors on Hypoglycemia Burden in the United States—A Predictive Modeling Approach

Diabetes ◽

10.2337/db18-385-p ◽

2018 ◽

Vol 67 (Supplement 1) ◽

pp. 385-P

Author(s):

JINAN LIU ◽

YUEXIN TANG ◽

HAKIMA HANNACHI ◽

SAMUEL S. ENGEL ◽

SWAPNIL RAJPATHAK

Keyword(s):

United States ◽

Predictive Modeling ◽

The United States ◽

Dipeptidyl Peptidase ◽

Dipeptidyl Peptidase 4 ◽

Modeling Approach ◽

Dipeptidyl Peptidase 4 Inhibitors

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2209-PUB: Factors Associated with Switching from Sulfonylureas (SUs) to Dipeptidyl Peptidase-4 Inhibitors (DPP-4i) among Individuals with Type 2 Diabetes in the United States

Diabetes ◽

10.2337/db20-2209-pub ◽

2020 ◽

Vol 69 (Supplement 1) ◽

pp. 2209-PUB

Author(s):

XI TAN ◽

LINGFENG YANG ◽

KAMLESH KHUNTI ◽

RUYA ZHANG ◽

DIANA ZHANG ◽

...

Keyword(s):

United States ◽

Type 2 Diabetes ◽

The United States ◽

Dipeptidyl Peptidase ◽

Dipeptidyl Peptidase 4 ◽

Factors Associated ◽

Dipeptidyl Peptidase 4 Inhibitors

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Gestational glucocorticoid exposure causes glucose dysregulation and increases dipeptidyl peptidase- 4 activity in rats

10.26226/morressier.59d51847d462b80296ca3d4c ◽

2017 ◽

Author(s):

Badmus Olufunto

Keyword(s):

Dipeptidyl Peptidase ◽

Dipeptidyl Peptidase 4 ◽

Glucose Dysregulation

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Faculty Opinions recommendation of Gliptin-associated Bullous Pemphigoid and the Expression of Dipeptidyl Peptidase-4/CD26 in Bullous Pemphigoid.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.735288467.793571813 ◽

2020 ◽

Author(s):

Silke Hofmann

Keyword(s):

Bullous Pemphigoid ◽

Dipeptidyl Peptidase ◽

Dipeptidyl Peptidase 4

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MK-0626, A Dipeptidyl Peptidase-4 Inhibitor, Improves Neovascularization by Increasing Both the Number of Circulating Endothelial Progenitor Cells and Endothelial Nitric Oxide Synthetase Expression

Current Medicinal Chemistry ◽

10.2174/09298673113206660273 ◽

2014 ◽

Vol 21 (17) ◽

pp. 2012-2022 ◽

Cited By ~ 22

Author(s):

Chun-Ming Shih ◽

Yung-Hsiang Chen ◽

Yi-Wen -Lin ◽

Nai-Wen Tsao ◽

Shinn-Chih Wu ◽

...

Keyword(s):

Nitric Oxide ◽

Progenitor Cells ◽

Endothelial Progenitor Cells ◽

Dipeptidyl Peptidase ◽

Endothelial Progenitor ◽

Dipeptidyl Peptidase 4 ◽

Nitric Oxide Synthetase ◽

Circulating Endothelial Progenitor Cells ◽

Dipeptidyl Peptidase 4 Inhibitor ◽

Endothelial Nitric Oxide

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Mechanisms of Neurodegeration in Type 2 Diabetes and the Neuroprotective Potential of Dipeptidyl Peptidase 4 Inhibitors

Current Medicinal Chemistry ◽

10.2174/0929867322666150227153308 ◽

2015 ◽

Vol 22 (13) ◽

pp. 1573-1581 ◽

Cited By ~ 21

Author(s):

E. Matteucci ◽

O. Giampietro

Keyword(s):

Type 2 Diabetes ◽

Dipeptidyl Peptidase ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitors

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Linagliptin: A Novel Xanthine-Based Dipeptidyl Peptidase-4 Inhibitor for Treatment of Type II Diabetes Mellitus

Current Diabetes Reviews ◽

10.2174/157339911797415648 ◽

2011 ◽

Vol 7 (5) ◽

pp. 325-335 ◽

Cited By ~ 8

Author(s):

Somsuvra B. Ghatak ◽

Devang S. Patel ◽

Neeraj Shanker ◽

Ambrish Srivastava ◽

Shrikalp S. Deshpande ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type Ii Diabetes ◽

Type Ii Diabetes Mellitus ◽

Dipeptidyl Peptidase ◽

Type Ii ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor

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