P24 Matrine ameliorates cognitive deficits and neuroinflammation via inhibition of microglial activation in an Alzheimer’s disease mouse model

Biochemical Pharmacology ◽

10.1016/j.bcp.2017.06.025 ◽

2017 ◽

Vol 139 ◽

pp. 132-133

Author(s):

Juan Li ◽

Yang Niu ◽

Huai-qin Han ◽

Wei-Qi Li ◽

Sangita Biswas ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Cognitive Deficits ◽

Microglial Activation

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Inhibition of Microglial Activation Protects Hippocampal Neurogenesis and Improves Cognitive Deficits in a Transgenic Mouse Model for Alzheimer’s Disease

Neurodegenerative Diseases ◽

10.1159/000330363 ◽

2012 ◽

Vol 9 (4) ◽

pp. 187-198 ◽

Cited By ~ 86

Author(s):

Barbara Biscaro ◽

Olle Lindvall ◽

Giuseppina Tesco ◽

Christine T. Ekdahl ◽

Roger M. Nitsch

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Cognitive Deficits ◽

Microglial Activation ◽

Transgenic Mouse Model ◽

Hippocampal Neurogenesis

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TLR4 mutation reduces microglial activation, increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease

Journal of Neuroinflammation ◽

10.1186/1742-2094-8-92 ◽

2011 ◽

Vol 8 (1) ◽

pp. 92 ◽

Cited By ~ 155

Author(s):

Min Song ◽

JingJi Jin ◽

Jeong-Eun Lim ◽

Jinghong Kou ◽

Abhinandan Pattanayak ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Cognitive Deficits ◽

Microglial Activation ◽

Model Of Alzheimer’S Disease

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Faculty Opinions recommendation of Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717977209.793470743 ◽

2013 ◽

Author(s):

Matt Kaeberlein

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Amyloid Beta ◽

Cognitive Deficits ◽

Model Of Alzheimer’S Disease

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Faculty Opinions recommendation of Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718520520.793504888 ◽

2015 ◽

Author(s):

Amy Barrios

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Cognitive Deficits ◽

Tyrosine Phosphatase ◽

Model Of Alzheimer’S Disease

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Faculty Opinions recommendation of A novel GLP-1/GIP/Gcg triagonist reduces cognitive deficits and pathology in the 3xTg mouse model of Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.732740978.793572425 ◽

2020 ◽

Author(s):

Venkateswarlu Kanamarlapudi

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Cognitive Deficits ◽

Model Of Alzheimer’S Disease

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Genetic ablation of the p66Shc adaptor protein reverses cognitive deficits and improves mitochondrial function in an APP transgenic mouse model of Alzheimer’s disease

Molecular Psychiatry ◽

10.1038/mp.2016.112 ◽

2016 ◽

Vol 22 (4) ◽

pp. 605-614 ◽

Cited By ~ 13

Author(s):

R Derungs ◽

G G Camici ◽

R D Spescha ◽

T Welt ◽

C Tackenberg ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Cognitive Deficits ◽

Mitochondrial Function ◽

Adaptor Protein ◽

Transgenic Mouse Model ◽

Genetic Ablation ◽

Model Of Alzheimer’S Disease

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F2-03-05: Aberrant Microglial Activation Contributes To Cognitive Deficits in Alzheimer's Disease

Alzheimer s & Dementia ◽

10.1016/j.jalz.2011.05.2451 ◽

2011 ◽

Vol 7 ◽

pp. S286-S287

Author(s):

Li Gan

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Deficits ◽

Microglial Activation

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P1-033: Cognitive deficits and plaque deposition in a gene-targeted mouse model of Alzheimer's disease

Alzheimer s & Dementia ◽

10.1016/j.jalz.2009.04.036 ◽

2009 ◽

Vol 5 (4S_Part_6) ◽

pp. P181-P181

Author(s):

John Ciallella ◽

Heather Hain ◽

Bryan Strenkowski ◽

Michelle Hogga ◽

Stacey Galvin ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Cognitive Deficits ◽

Plaque Deposition ◽

Model Of Alzheimer’S Disease

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Oral administration of methysticin improves cognitive deficits in a mouse model of Alzheimer's disease

Redox Biology ◽

10.1016/j.redox.2017.04.024 ◽

2017 ◽

Vol 12 ◽

pp. 843-853 ◽

Cited By ~ 30

Author(s):

Athanassios Fragoulis ◽

Stephanie Siegl ◽

Markus Fendt ◽

Sandra Jansen ◽

Ulf Soppa ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Oral Administration ◽

Cognitive Deficits ◽

Model Of Alzheimer’S Disease

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Astragaloside IV ameliorates cognitive impairment and neuroinflammation in an oligomeric Aβ induced Alzheimer's disease mouse model via inhibition of microglial activation and NADPH oxidase expression

Biological and Pharmaceutical Bulletin ◽

10.1248/bpb.b21-00381 ◽

2021 ◽

Cited By ~ 1

Author(s):

Fei Chen ◽

Dan Yang ◽

Xiao-Yu Cheng ◽

Hui Yang ◽

Xin-He Yang ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mouse Model ◽

Nadph Oxidase ◽

Microglial Activation ◽

Astragaloside Iv

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