CCR2-engineered mesenchymal stromal cells accelerate diabetic wound healing by restoring immunological homeostasis

Biomaterials ◽  
2021 ◽  
pp. 120963
Author(s):  
Shuhong Kuang ◽  
Feng He ◽  
Guihua Liu ◽  
Xiangzhou Sun ◽  
Jian Dai ◽  
...  
Keyword(s):  
Wound Healing ◽  
Mesenchymal Stromal Cells ◽  
Stromal Cells ◽  
Diabetic Wound ◽  
Diabetic Wound Healing ◽  
Immunological Homeostasis

scholarly journals Human Adipose-Derived Stromal Cells Accelerate Diabetic Wound Healing: Impact of Cell Formulation and Delivery

2010 ◽  
Vol 16 (5) ◽  
pp. 1595-1606 ◽  
Author(s):  
Peter J. Amos ◽  
Sahil K. Kapur ◽  
Peter C. Stapor ◽  
Hulan Shang ◽  
Stefan Bekiranov ◽  
...  
Keyword(s):  
Wound Healing ◽  
Stromal Cells ◽  
Diabetic Wound ◽  
Adipose Derived Stromal Cells ◽  
Diabetic Wound Healing

In vitro characterization of human hair follicle dermal sheath mesenchymal stromal cells and their potential in enhancing diabetic wound healing

Cytotherapy ◽  
2015 ◽  
Vol 17 (8) ◽  
pp. 1036-1051 ◽  
Author(s):  
Dongrui Ma ◽  
Jonah Ee Hsiang Kua ◽  
Wee Keng Lim ◽  
Seng Teik Lee ◽  
Alvin Wen Choong Chua
Keyword(s):  
Wound Healing ◽  
Hair Follicle ◽  
Stromal Cells ◽  
Human Hair ◽  
Diabetic Wound ◽  
Human Hair Follicle ◽  
In Vitro Characterization ◽  
Diabetic Wound Healing

The diabetic wound healing effect of a two-herb formula and its mechanisms of action

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
CBS Lau ◽  
VKM Lau ◽  
CL Liu ◽  
PKK Lai ◽  
JCW Tam ◽  
...  
Keyword(s):  
Wound Healing ◽  
Mechanisms Of Action ◽  
Diabetic Wound ◽  
Healing Effect ◽  
Diabetic Wound Healing ◽  
Wound Healing Effect

Critical Regulation of Angiogenesis by Nrf2 Signaling Is Absent in Diabetic Wound Healing

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 634-P
Author(s):  
PIUL S. RABBANI ◽  
JOSHUA A. DAVID ◽  
DARREN L. SULTAN ◽  
ALVARO P. VILLARREAL-PONCE ◽  
JENNIFER KWONG ◽  
...  
Keyword(s):  
Wound Healing ◽  
Diabetic Wound ◽  
Diabetic Wound Healing

A bioglass sustained-release scaffold with ECM-like structure for enhanced diabetic wound healing

Nanomedicine ◽  
2020 ◽  
Vol 15 (23) ◽  
pp. 2241-2253
Author(s):  
Pengju Zhang ◽  
Yuqi Jiang ◽  
Dan Liu ◽  
Yan Liu ◽  
Qinfei Ke ◽  
...  
Keyword(s):  
Wound Healing ◽  
Therapeutic Option ◽  
Effective Strategy ◽  
Diabetic Wound ◽  
Nano Structure ◽  
Wound Site ◽  
Diabetic Wound Healing ◽  
Coaxial Fibers ◽  
Diabetic Wounds ◽  
Endothelial Cell Adhesion

Aim: To develop an effective strategy for increasing angiogenesis at diabetic wound sites and thereby accelerating wound healing. Materials & methods: A micropatterned nanofibrous scaffold with bioglass nanoparticles encapsulated inside coaxial fibers was prepared by electrospinning. Results: Si ions could be released in a sustained manner from the scaffolds. The hierarchical micro-/nano-structure of the scaffold was found to act as a temporary extracellular matrix to promote endothelial cell adhesion and growth. The scaffold greatly improved angiogenesis and collagen deposition at the wound site, which shortened the healing period of diabetic wounds. Conclusion: This study provides a promising therapeutic option for chronic diabetic wounds with improved angiogenesis.

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