New quinoxaline derivatives as VEGFR-2 inhibitors with anticancer and apoptotic activity: Design, molecular modeling, and synthesis

Bioorganic Chemistry ◽

10.1016/j.bioorg.2021.104807 ◽

2021 ◽

pp. 104807

Author(s):

Nawaf A. Alsaif ◽

Mohammed A. Dahab ◽

Mohammed M. Alanazi ◽

Ahmad J. Obiadullah ◽

Abdulrahman A. Al-Mehizia ◽

...

Keyword(s):

Molecular Modeling ◽

Quinoxaline Derivatives ◽

Apoptotic Activity ◽

Activity Design

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Design, synthesis, molecular modeling and anti-proliferative evaluation of novel quinoxaline derivatives as potential DNA intercalators and topoisomerase II inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2018.06.004 ◽

2018 ◽

Vol 155 ◽

pp. 117-134 ◽

Cited By ~ 34

Author(s):

M.K. Ibrahim ◽

M.S. Taghour ◽

A.M. Metwaly ◽

A. Belal ◽

A.B.M. Mehany ◽

...

Keyword(s):

Molecular Modeling ◽

Topoisomerase Ii ◽

Design Synthesis ◽

Dna Intercalators ◽

Topoisomerase Ii Inhibitors ◽

Quinoxaline Derivatives

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1,2,4-Triazolo[1,5-a]quinoxaline derivatives and their simplified analogues as adenosine A3 receptor antagonists. Synthesis, structure–affinity relationships and molecular modeling studies

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2014.11.033 ◽

2015 ◽

Vol 23 (1) ◽

pp. 9-21 ◽

Cited By ~ 13

Author(s):

Daniela Catarzi ◽

Flavia Varano ◽

Daniela Poli ◽

Lucia Squarcialupi ◽

Marco Betti ◽

...

Keyword(s):

Molecular Modeling ◽

Receptor Antagonists ◽

Adenosine A3 Receptor ◽

Modeling Studies ◽

Quinoxaline Derivatives ◽

Molecular Modeling Studies

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Design, synthesis, molecular modeling and anti-hyperglycemic evaluation of novel quinoxaline derivatives as potential PPARγ and SUR agonists

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2017.01.015 ◽

2017 ◽

Vol 25 (4) ◽

pp. 1496-1513 ◽

Cited By ~ 22

Author(s):

Mohammed K. Ibrahim ◽

Ibrahim H. Eissa ◽

Abdallah E. Abdallah ◽

Ahmed M. Metwaly ◽

M.M. Radwan ◽

...

Keyword(s):

Molecular Modeling ◽

Design Synthesis ◽

Quinoxaline Derivatives

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3-Methylthiazolo[3,2-a]benzimidazole-benzenesulfonamide conjugates as novel carbonic anhydrase inhibitors endowed with anticancer activity: Design, synthesis, biological and molecular modeling studies

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2020.112745 ◽

2020 ◽

Vol 207 ◽

pp. 112745 ◽

Cited By ~ 2

Author(s):

Abdulsalam A.M. Alkhaldi ◽

Mohammad M. Al-Sanea ◽

Alessio Nocentini ◽

Wagdy M. Eldehna ◽

Zainab M. Elsayed ◽

...

Keyword(s):

Molecular Modeling ◽

Carbonic Anhydrase ◽

Anticancer Activity ◽

Carbonic Anhydrase Inhibitors ◽

Design Synthesis ◽

Modeling Studies ◽

Molecular Modeling Studies ◽

Activity Design

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Molecular modeling studies and synthesis of novel quinoxaline derivatives with potential anti-cancer activity as inhibitors of methionine synthase

Medicinal Chemistry Research ◽

10.1007/s00044-012-0307-4 ◽

2012 ◽

Vol 22 (7) ◽

pp. 3405-3415

Author(s):

Hosam Elshihawy ◽

Mohamed Hammad

Keyword(s):

Molecular Modeling ◽

Methionine Synthase ◽

Modeling Studies ◽

Anti Cancer ◽

Quinoxaline Derivatives ◽

Molecular Modeling Studies ◽

Cancer Activity

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Molecular modeling studies and synthesis of novel quinoxaline derivatives with potential anticancer activity as inhibitors of c-Met kinase

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2015.09.023 ◽

2015 ◽

Vol 23 (20) ◽

pp. 6560-6572 ◽

Cited By ~ 33

Author(s):

Hebat-Allah S. Abbas ◽

Aisha R. Al-Marhabi ◽

Sally I. Eissa ◽

Yousry A. Ammar

Keyword(s):

Molecular Modeling ◽

Anticancer Activity ◽

Modeling Studies ◽

Quinoxaline Derivatives ◽

Molecular Modeling Studies

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Synthesis, Molecular modeling and biological evaluation of indeno[1,2-b]quinoxaline derivatives as antifungal and antibacterial agents.

Egyptian Journal of Chemistry ◽

10.21608/ejchem.2020.21366.2275 ◽

2020 ◽

Vol 0 (0) ◽

pp. 0-0

Author(s):

hayam Abdelsalaam ◽

fatma el-samahy

Keyword(s):

Molecular Modeling ◽

Antibacterial Agents ◽

Biological Evaluation ◽

Quinoxaline Derivatives

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Molecular Modeling of Nucleic Acids

10.1021/bk-1998-0682 ◽

1997 ◽

Cited By ~ 4

Keyword(s):

Molecular Modeling ◽

Nucleic Acids

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Molecular Modeling of the Interaction of LSD and Other Hallucinogens With 5-HT2 Receptors

PsycEXTRA Dataset ◽

10.1037/e495832006-014 ◽

1994 ◽

Author(s):

Richard B. Westkaemper ◽

◽

Richard A. Glennon

Keyword(s):

Molecular Modeling

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The Use of Conformational Restriction and Molecular Modeling Techniques in the Development of Receptor-Specific Opioid Peptide Agonists and Antagonists

PsycEXTRA Dataset ◽

10.1037/e495942006-018 ◽

1993 ◽

Author(s):

Peter W. Schiller ◽

◽

Thi M.-D. Nguyen ◽

Grazyna Weltrowska ◽

Nga N. Chung ◽

...

Keyword(s):

Molecular Modeling ◽

Opioid Peptide ◽

Conformational Restriction ◽

Modeling Techniques

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