Three-dimensional interdigitated electrode array as a transducer for label-free biosensors

2008 ◽  
Vol 24 (4) ◽  
pp. 729-735 ◽  
Author(s):  
Andrey Bratov ◽  
Javier Ramón-Azcón ◽  
Natalia Abramova ◽  
Angel Merlos ◽  
Javier Adrian ◽  
...  
2011 ◽  
Vol 24 (1) ◽  
pp. 69-75 ◽  
Author(s):  
Andrey Bratov ◽  
Natalia Abramova ◽  
M. Pilar Marco ◽  
Francisco Sanchez-Baeza

2009 ◽  
Vol 1236 ◽  
Author(s):  
Allison M Whited ◽  
Kanwar V Singh ◽  
Raj Solanki ◽  
David R Evans

AbstractCA-125 and carcinoembryonic antigen (CEA) are two biomarkers present in blood that can indicate the presence of ovarian cancer. They can also be used, both in conjunction with each other and independently, to determine the effectiveness of the treatment being meted for the disease. A label-free multiplexed interdigitated electrode array (IDEA) immunosensor was developed to detect both CA-125 and CEA in buffer solution at levels typically seen in patients with ovarian cancer . Electrochemical impedance spectroscopy was used to measure the increase in impedance when a binding event occurred between the target antigen and its specific antibody that was anchored to the surface of an interdigitated electrode array. CA-125 was detected in concentrations as low as 10units/mL and as high as 80units/mL. CEA was detected in concentrations as low as 1pg/mL and as high as 10μg/mL.


2016 ◽  
Vol 88 (19) ◽  
pp. 9582-9589 ◽  
Author(s):  
Yuwadee Boonyasit ◽  
Wanida Laiwattanapaisal ◽  
Orawon Chailapakul ◽  
Jenny Emnéus ◽  
Arto R. Heiskanen

Langmuir ◽  
2011 ◽  
Vol 27 (22) ◽  
pp. 13931-13939 ◽  
Author(s):  
Kanwar V. Singh ◽  
Dheeraj K. Bhura ◽  
Gopichand Nandamuri ◽  
Allison M. Whited ◽  
David Evans ◽  
...  

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