scholarly journals Heterogeneous impact of hypotension on organ perfusion and outcomes: a narrative review

Author(s):  
Lingzhong Meng
2019 ◽  
Vol 123 (2) ◽  
pp. 170-176 ◽  
Author(s):  
Thomas Parker ◽  
David Brealey ◽  
Alex Dyson ◽  
Mervyn Singer

Anaesthesia ◽  
2001 ◽  
Vol 56 (12) ◽  
pp. 1154-1159 ◽  
Author(s):  
M. Schmidt ◽  
T. Marx ◽  
J. Kotzerke ◽  
S. Luderwald ◽  
S. Armbruster ◽  
...  
Keyword(s):  

2017 ◽  
Vol 23 ◽  
pp. 60
Author(s):  
Altamash Shaikh ◽  
Anuj Maheshwari ◽  
Banshi Saboo ◽  
Ashok Jhingan ◽  
Shriram Kulkarni ◽  
...  

2004 ◽  
Vol 52 (S 1) ◽  
Author(s):  
A Liebold ◽  
C Wiesenack ◽  
C Prasser ◽  
A Philipp ◽  
M Jagiello ◽  
...  
Keyword(s):  

1972 ◽  
Vol 68 (2_Supplb) ◽  
pp. S9-S25 ◽  
Author(s):  
John Urquhart ◽  
Nancy Keller

ABSTRACT Two techniques for organ perfusion with blood are described which provide a basis for exploring metabolic or endocrine dynamics. The technique of in situ perfusion with autogenous arterial blood is suitable for glands or small organs which receive a small fraction of the animal's cardiac output; thus, test stimulatory or inhibitory substances can be added to the perfusing blood and undergo sufficient dilution in systemic blood after passage through the perfused organ so that recirculation does not compromise experimental control over test substance concentration in the perfusate. Experimental studies with the in situ perfused adrenal are described. The second technique, termed the pilot organ method, is suitable for organs which receive a large fraction of the cardiac output, such as the liver. Vascular connections are made between the circulation of an intact, anaesthetized large (> 30 kg) dog and the liver of a small (< 3 kg) dog. The small dog's liver (pilot liver) is excised and floated in a bath of canine ascites, and its venous effluent is continuously returned to the large dog. Test substances are infused into either the hepatic artery or portal vein of the pilot liver, but the small size of the pilot liver and its blood flow in relation to the large dog minimize recirculation effects. A number of functional parameters of the pilot liver are described.


1972 ◽  
Vol 68 (2_Supplb) ◽  
pp. S44-S73 ◽  
Author(s):  
Eugene F. Bernstein

ABSTRACT Among the critical factors in organ perfusion are (1) the mechanical components of the system, (2) the composition of the perfusate, and (3) the perfusing conditions. In this review, particular consideration is given to the pump, the oxygenator, and cannulas in such systems. Emphasis is placed upon the selection of pertinent equipment for the goals of a particular perfusion experiment, based upon the criteria of adequacy of the perfusion. Common problems in organ perfusion are summarized, and potential solutions to the perfusion problem, involving either biologic or mechanical extracorporeal systems, are suggested.


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