Synthesis and anti-hepatitis C virus activity of novel ethyl 1H-indole-3-carboxylates in vitro

2010 ◽  
Vol 18 (16) ◽  
pp. 6143-6148 ◽  
Author(s):  
Grazia Sellitto ◽  
Aurora Faruolo ◽  
Paolo de Caprariis ◽  
Sergio Altamura ◽  
Giacomo Paonessa ◽  
...  
2006 ◽  
Vol 50 (10) ◽  
pp. 3444-3446 ◽  
Author(s):  
Lotte Coelmont ◽  
Jan Paeshuyse ◽  
Marc P. Windisch ◽  
Erik De Clercq ◽  
Ralf Bartenschlager ◽  
...  

ABSTRACT Ribavirin antagonizes the in vitro anti-hepatitis C virus (HCV) activity of the pyrimidine nucleoside analogue 2′-C-methylcytidine, the active component of the experimental anti-HCV drug valopicitabine. In contrast, the combination of ribavirin with either the purine nucleoside analogue 2′-C-methyladenosine or the HCV protease inhibitor VX-950 resulted in an additive antiviral activity. These findings may have implications when planning clinical studies with valopicitabine.


Molecules ◽  
2016 ◽  
Vol 21 (10) ◽  
pp. 1367 ◽  
Author(s):  
Shao-Ru Chen ◽  
An-Qi Wang ◽  
Li-Gen Lin ◽  
Hong-Cong Qiu ◽  
Yi-Tao Wang ◽  
...  

2011 ◽  
Vol 54 ◽  
pp. S487 ◽  
Author(s):  
A.S. Ray ◽  
J.Y. Feng ◽  
T. Wang ◽  
K. Wong ◽  
L. Zhang ◽  
...  

2020 ◽  
Vol 10 (09) ◽  
pp. 463-477 ◽  
Author(s):  
Dina Mofed ◽  
Wafaa Ahmed ◽  
Abdel-Rahman Zekri ◽  
Ola Said ◽  
Mohamed Rahouma ◽  
...  

2006 ◽  
Vol 44 (08) ◽  
Author(s):  
P Hilgard ◽  
R Bröring ◽  
M Trippler ◽  
S Viazov ◽  
G Gerken ◽  
...  

1997 ◽  
Vol 71 (9) ◽  
pp. 6373-6380 ◽  
Author(s):  
L Pieroni ◽  
E Santolini ◽  
C Fipaldini ◽  
L Pacini ◽  
G Migliaccio ◽  
...  

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