Soluble epoxide hydrolase inhibitory activity of anthraquinone components from Aloe

2015 ◽  
Vol 23 (20) ◽  
pp. 6659-6665 ◽  
Author(s):  
Ya Nan Sun ◽  
Jang Hoon Kim ◽  
Wei Li ◽  
A. Reum Jo ◽  
Xi Tao Yan ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Epoxide Hydrolase ◽  
Soluble Epoxide Hydrolase

scholarly journals IN VITRO SOLUBLE EPOXIDE HYDROLASE ENZYME INHIBITORY ACTIVITY OF SOME NOVEL CHALCONE DERIVATIVES

2012 ◽  
Vol 2 (4) ◽  
Author(s):  
Kuppusamy Asokkumar ◽  
Lokeswari Prathyusha Tangella ◽  
Muthusamy Umamaheshwari ◽  
Thirumalaisamy Shivashanmugam ◽  
Varadharajan Subhadradevi ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Epoxide Hydrolase ◽  
Soluble Epoxide Hydrolase ◽  
Chalcone Derivatives

Soluble epoxide hydrolase inhibitory activity of anthraquinone components from Aloe

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
YN Sun ◽  
AR Jo ◽  
JH Kim ◽  
JS Kang ◽  
YH Kim
Keyword(s):  
Inhibitory Activity ◽  
Epoxide Hydrolase ◽  
Soluble Epoxide Hydrolase

scholarly journals Soluble Epoxide Hydrolase Inhibitory Activity of Components Isolated from Apios americana Medik

Molecules ◽  
2017 ◽  
Vol 22 (9) ◽  
pp. 1432 ◽  
Author(s):  
Jang Kim ◽  
Hyo Kim ◽  
Si Kang ◽  
Young Kim ◽  
Chang Jin
Keyword(s):  
Inhibitory Activity ◽  
Epoxide Hydrolase ◽  
Soluble Epoxide Hydrolase ◽  
Apios Americana

scholarly journals Sorafenib has soluble epoxide hydrolase inhibitory activity, which contributes to its effect profile in vivo

2009 ◽  
Vol 8 (8) ◽  
pp. 2193-2203 ◽  
Author(s):  
Jun-Yan Liu ◽  
See-Hyoung Park ◽  
Christophe Morisseau ◽  
Sung Hee Hwang ◽  
Bruce D. Hammock ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Epoxide Hydrolase ◽  
Soluble Epoxide Hydrolase

scholarly journals 2-(Piperidin-4-yl)acetamides as Potent Inhibitors of Soluble Epoxide Hydrolase with Anti-Inflammatory Activity

2021 ◽  
Vol 14 (12) ◽  
pp. 1323
Author(s):  
Juan Martín-López ◽  
Sandra Codony ◽  
Clara Bartra ◽  
Christophe Morisseau ◽  
María Isabel Loza ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Epoxide Hydrolase ◽  
Inflammatory Diseases ◽  
Soluble Epoxide Hydrolase ◽  
Inflammatory Activity ◽  
Epoxyeicosatrienoic Acids ◽  
Pharmacological Inhibition ◽  
Anti Inflammatory ◽  
Further Development ◽  
Potent Inhibitory Activity

The pharmacological inhibition of soluble epoxide hydrolase (sEH) has been suggested as a potential therapy for the treatment of pain and inflammatory diseases through the stabilization of endogenous epoxyeicosatrienoic acids. Numerous potent sEH inhibitors (sEHI) have been developed, however many contain highly lipophilic substituents limiting their availability. Recently, a new series of benzohomoadamantane-based ureas endowed with potent inhibitory activity for the human and murine sEH was reported. However, their very low microsomal stability prevented further development. Herein, a new series of benzohomoadamantane-based amides were synthetized, fully characterized, and evaluated as sEHI. Most of these amides were endowed with excellent inhibitory potencies. A selected compound displayed anti-inflammatory effects with higher effectiveness than the reference sEHI, TPPU.

Soluble epoxide hydrolase inhibitory activity of phenolic components from the rhizomes and roots ofGentiana scabra

2015 ◽  
Vol 79 (6) ◽  
pp. 907-911 ◽  
Author(s):  
Wei Li ◽  
Jang Hoon Kim ◽  
Wei Zhou ◽  
Sang Hee Shim ◽  
Jin Yeul Ma ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Epoxide Hydrolase ◽  
Soluble Epoxide Hydrolase ◽  
Phenolic Components

Soluble epoxide hydrolase inhibitory activity by rhizomes of Kaempferia parviflora Wall. ex Baker

2016 ◽  
Vol 25 (4) ◽  
pp. 704-711 ◽  
Author(s):  
Nguyen Phuong Thao ◽  
Bui Thi Thuy Luyen ◽  
Jang Hoon Kim ◽  
Ah Reum Jo ◽  
Seo Young Yang ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Epoxide Hydrolase ◽  
Soluble Epoxide Hydrolase ◽  
Kaempferia Parviflora

Soluble epoxide hydrolase inhibitory activity of phenolic glycosides from Polygala tenuifolia and in silico approach

2017 ◽  
Vol 27 (3) ◽  
pp. 726-734 ◽  
Author(s):  
Le Ba Vinh ◽  
Jang Hoon Kim ◽  
Ji Sun Lee ◽  
Nguyen Thi Minh Nguyet ◽  
Seo Young Yang ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
In Silico ◽  
Epoxide Hydrolase ◽  
Soluble Epoxide Hydrolase ◽  
Phenolic Glycosides ◽  
Polygala Tenuifolia
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