Synthesis and immunological evaluation of N-acyl modified Tn analogues as anticancer vaccine candidates

2016 ◽  
Vol 24 (4) ◽  
pp. 915-920 ◽  
Author(s):  
Chengcheng Song ◽  
Shuang Sun ◽  
Chang-Xin Huo ◽  
Qin Li ◽  
Xiu-Jing Zheng ◽  
...  
Keyword(s):  
Vaccine Candidates ◽  
Anticancer Vaccine ◽  
Immunological Evaluation

Synthesis and immunological evaluation of N-acyl modified Globo H derivatives as anticancer vaccine candidates

2021 ◽  
Author(s):  
Canjia Zhai ◽  
Xiu-Jing Zheng ◽  
Cheng-Cheng Song ◽  
Xin-Shan Ye
Keyword(s):  
T Cell ◽  
Carbohydrate Antigen ◽  
Vaccine Candidates ◽  
Antitumor Vaccine ◽  
Cancer Immunotherapies ◽  
Anticancer Vaccine ◽  
Immunological Evaluation

Globo H is a tumor-associated carbohydrate antigen (TACA), which serves as a valuable target for antitumor vaccine or cancer immunotherapies. However, most TACAs are T-cell-independent and they cannot induce powerful...

scholarly journals Synthesis and immunological evaluation of synthetic peptide based anti-SARS-CoV-2 vaccine candidates

2021 ◽  
Author(s):  
Qingyu Zhao ◽  
Yanan Gao ◽  
Min Xiao ◽  
Xuefei Huang ◽  
Xuanjun Wu
Keyword(s):  
Synthetic Peptide ◽  
Spike Protein ◽  
Effective Vaccine ◽  
The Novel ◽  
Vaccine Candidates ◽  
Peptide Epitopes ◽  
Novel Coronavirus ◽  
Immunological Evaluation

For prevention of the coronavirus disease 2019 caused by the novel coronavirus SARS-CoV-2, an effective vaccine is critical. Herein, several potential peptide epitopes from the spike protein of SARS-CoV-2 have...

Syntheses and Immunological Evaluation of Self‐Adjuvanting Clustered N ‐Acetyl and N ‐Propionyl Sialyl‐Tn Combined with a T‐helper Cell Epitope as Antitumor Vaccine Candidates

2018 ◽  
Vol 130 (27) ◽  
pp. 8351-8356 ◽  
Author(s):  
Tsung‐Che Chang ◽  
Yoshiyuki Manabe ◽  
Yukari Fujimoto ◽  
Shino Ohshima ◽  
Yoshie Kametani ◽  
...  
Keyword(s):  
Cell Epitope ◽  
T Helper Cell ◽  
Helper Cell ◽  
T Helper ◽  
Vaccine Candidates ◽  
Antitumor Vaccine ◽  
Immunological Evaluation ◽  
Sialyl Tn

scholarly journals Chemical synthesis and immunological evaluation of new generation multivalent anticancer vaccines based on a Tn antigen analogue

2020 ◽  
Vol 11 (17) ◽  
pp. 4488-4498
Author(s):  
Carlo Pifferi ◽  
Ane Ruiz-de-Angulo ◽  
David Goyard ◽  
Claire Tiertant ◽  
Nagore Sacristán ◽  
...  
Keyword(s):  
Igg Antibodies ◽  
Tn Antigen ◽  
Cellular Immune Responses ◽  
Anticancer Vaccines ◽  
Specific Igg ◽  
Cellular Immune ◽  
New Generation ◽  
Anticancer Vaccine ◽  
Immunological Evaluation ◽  
Specific Igg Antibodies

A fully-synthetic anticancer vaccine candidate incorporating an hexadecavalent Tn antigen analogue display via oxime linkages induced tumor-specific IgG antibodies and cellular immune responses in mice coadministered with QS-21 as an adjuvant.

Quantum Chemical and Molecular Dynamics Studies of MUC1 Calix[4,8]arene Scaffold Based Anticancer Vaccine Candidates

2020 ◽  
Vol 60 (10) ◽  
pp. 5162-5171
Author(s):  
Angelo Spadaro ◽  
Livia Basile ◽  
Matteo Pappalardo ◽  
Carmela Bonaccorso ◽  
Marco Rao ◽  
...  
Keyword(s):  
Molecular Dynamics ◽  
Quantum Chemical ◽  
Vaccine Candidates ◽  
Anticancer Vaccine

Synthesis and Evaluation of Anticancer Vaccine Candidates,C-Glycoside Analogs of STn and PSA

2008 ◽  
pp. 216-238 ◽  
Author(s):  
Michel Weïwer ◽  
Fei Huang ◽  
Chi-Chang Chen ◽  
Xuejun Yuan ◽  
Kazuo Tokuzaki ◽  
...  
Keyword(s):  
Vaccine Candidates ◽  
Anticancer Vaccine

scholarly journals Synthesis and immunological evaluation of peptide-based vaccine candidates against malaria

2016 ◽  
Vol 4 (1) ◽  
pp. 1 ◽  
Author(s):  
Saranya Chandrudu ◽  
Mariusz Skwarczynski ◽  
David Pattinson ◽  
Simon H Apte ◽  
Denise L Doolan ◽  
...  
Keyword(s):  
Vaccine Candidates ◽  
Immunological Evaluation
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