Synthesis, biological evaluation and molecular modeling study of [1,2,4]-Triazolo[4,3-c]quinazolines: New class of EGFR-TK inhibitors

Tk Inhibitors ◽

Thiazolo[4,5- d ]pyridazine analogues as a new class of dihydrofolate reductase (DHFR) inhibitors: Synthesis, biological evaluation and molecular modeling study

Bioorganic Chemistry ◽

10.1016/j.bioorg.2017.08.010 ◽

2017 ◽

Vol 74 ◽

pp. 228-237 ◽

Cited By ~ 8

Author(s):

Menna A. Ewida ◽

Dalal A. Abou El Ella ◽

Deena S. Lasheen ◽

Heba A. Ewida ◽

Yomna I. El-Gazzar ◽

...

Keyword(s):

Molecular Modeling ◽

Dihydrofolate Reductase ◽

Biological Evaluation ◽

New Class ◽

Dhfr Inhibitors ◽

Thiadiazolodiazepine analogues as a new class of neuromuscular blocking agents: Synthesis, biological evaluation and molecular modeling study

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2016.09.096 ◽

2017 ◽

Vol 126 ◽

pp. 15-23 ◽

Cited By ~ 2

Author(s):

Hussein I. El-Subbagh ◽

Adel S. El-Azab ◽

Ghada S. Hassan ◽

Shahenda M. El-Messery ◽

Alaa A.-M. Abdel-Aziz ◽

...

Keyword(s):

Molecular Modeling ◽

Biological Evaluation ◽

Neuromuscular Blocking ◽

Neuromuscular Blocking Agents ◽

New Class ◽

Blocking Agents ◽

Nonclassical antifolates, part 4. 5-(2-Aminothiazol-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiols as a new class of DHFR inhibitors: Synthesis, biological evaluation and molecular modeling study

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2013.05.039 ◽

2013 ◽

Vol 66 ◽

pp. 135-145 ◽

Cited By ~ 38

Author(s):

Ghada S. Hassan ◽

Shahenda M. El-Messery ◽

Fatmah A.M. Al-Omary ◽

Sarah T. Al-Rashood ◽

Marwa I. Shabayek ◽

...

Keyword(s):

Molecular Modeling ◽

Biological Evaluation ◽

New Class ◽

Dhfr Inhibitors ◽

Synthesis, biological evaluation and molecular modeling study of 2-(1,3,4-thiadiazolyl-thio and 4-methyl-thiazolyl-thio)-quinazolin-4-ones as a new class of DHFR inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2014.07.070 ◽

2014 ◽

Vol 24 (18) ◽

pp. 4557-4567 ◽

Cited By ~ 24

Author(s):

Sarah T. Al-Rashood ◽

Ghada S. Hassan ◽

Shahenda M. El-Messery ◽

Mahmoud N. Nagi ◽

El-Sayed E. Habib ◽

...

Keyword(s):

Molecular Modeling ◽

Biological Evaluation ◽

New Class ◽

Dhfr Inhibitors ◽

Synthesis, biological evaluation and molecular modeling study of thiadiazolo[3,2- a ][1,3]diazepine analogues of HIE-124 as a new class of short acting hypnotics

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2016.08.038 ◽

2016 ◽

Vol 124 ◽

pp. 237-247 ◽

Cited By ~ 4

Author(s):

Hussein I. El-Subbagh ◽

Ghada S. Hassan ◽

Kamal E.H. El-Taher ◽

Shahenda M. El-Messery ◽

Adel S. Al-Azab ◽

...

Keyword(s):

Molecular Modeling ◽

Biological Evaluation ◽

Short Acting ◽

New Class ◽

Molecular modeling study, synthesis and biological evaluation of combretastatin A-4 analogues as anticancer agents and tubulin inhibitors

MedChemComm ◽

10.1039/c7md00416h ◽

2018 ◽

Vol 9 (2) ◽

pp. 316-327 ◽

Cited By ~ 2

Author(s):

Yang Ping Quan ◽

Li Ping Cheng ◽

Tian Chi Wang ◽

Wan Pang ◽

Fan Hong Wu ◽

...

Keyword(s):

Molecular Modeling ◽

Anticancer Agents ◽

Hepg2 Cells ◽

Binding Mode ◽

Biological Evaluation ◽

Tubulin Inhibitors ◽

Synthesis And Biological Evaluation ◽

Compound 13a, more effective than CA-4 against HepG2 cells and tubulin, and the proposed binding mode for 13a.

Design, synthesis and biological evaluation of estradiol-PEG-linked platinum(II) hybrid molecules: Comparative molecular modeling study of three distinct families of hybrids

Steroids ◽

10.1016/j.steroids.2010.09.004 ◽

2011 ◽

Vol 76 (1-2) ◽

pp. 94-103 ◽

Cited By ~ 28

Author(s):

Josée Provencher-Mandeville ◽

Chhanda Debnath ◽

Sanat K. Mandal ◽

Valérie Leblanc ◽

Sophie Parent ◽

...

Keyword(s):

Molecular Modeling ◽

Biological Evaluation ◽

Design Synthesis ◽

Hybrid Molecules ◽

Synthesis And Biological Evaluation ◽

Synthesis, biological evaluation and molecular modeling study of pyrazole derivatives as selective COX-2 inhibitors and anti-inflammatory agents

Bioorganic Chemistry ◽

10.1016/j.bioorg.2014.05.004 ◽

2014 ◽

Vol 56 ◽

pp. 8-15 ◽

Cited By ~ 41

Author(s):

Ashish Kumar Tewari ◽

Ved Prakash Singh ◽

Pratima Yadav ◽

Garima Gupta ◽

Amit Singh ◽

...

Keyword(s):

Molecular Modeling ◽

Biological Evaluation ◽

Pyrazole Derivatives ◽

Cox 2 ◽

Anti Inflammatory ◽

Cox 2 Inhibitors ◽

Synthesis and biological evaluation of novel 6-nitro-5-substituted aminoquinolines as local anesthetic and anti-arrhythmic agents: molecular modeling study

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2005.02.050 ◽

2005 ◽

Vol 13 (9) ◽

pp. 3175-3183 ◽

Cited By ~ 25

Author(s):

Fatma E. Goda ◽

Alaa A.-M. Abdel-Aziz ◽

Hamdy A. Ghoneim

Keyword(s):

Molecular Modeling ◽

Local Anesthetic ◽

Biological Evaluation ◽

Synthesis And Biological Evaluation ◽

Synthesis, biological evaluation and molecular modeling study of 2-amino-3,5-disubstituted-pyrazines as Aurora kinases inhibitors

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2020.115351 ◽

2020 ◽

Vol 28 (5) ◽

pp. 115351 ◽

Cited By ~ 1

Author(s):

Yong-Xin Bo ◽

Rong Xiang ◽

Yu Xu ◽

Shu-Yi Hao ◽

Xing-Rong Wang ◽

...

Keyword(s):

Molecular Modeling ◽

Biological Evaluation ◽

Aurora Kinases ◽