Discovery of Pyrazolo[1,5-a]pyrazin-4-ones as Potent and Brain Penetrant GluN2A-Selective Positive Allosteric Modulators Reducing AMPA Receptor Binding Activity

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2021.116576 ◽

2021 ◽

pp. 116576

Author(s):

Fumie Sakurai ◽

Takafumi Yukawa ◽

Asato Kina ◽

Masataka Murakami ◽

Kazuaki Takami ◽

...

Keyword(s):

Ampa Receptor ◽

Receptor Binding ◽

Binding Activity ◽

Allosteric Modulators ◽

Receptor Binding Activity ◽

Positive Allosteric Modulators

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Role of sulfhydryl groups in Y2 neuropeptide Y receptor binding activity.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)42554-9 ◽

1992 ◽

Vol 267 (11) ◽

pp. 7570-7575 ◽

Cited By ~ 1

Author(s):

W Li ◽

R.G. MacDonald ◽

T.D. Hexum

Keyword(s):

Neuropeptide Y ◽

Receptor Binding ◽

Binding Activity ◽

Sulfhydryl Groups ◽

Neuropeptide Y Receptor ◽

Receptor Binding Activity

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RADIOIMMUNOASSAY OF METHIONINE ENKEPHALIN AND INTERFERENCE BY BRAIN FACTOR OF IM MUNOREACTI VIT Y AND OPIATE RECEPTOR BINDING ACTIVITY

The Japanese Journal of Pharmacology ◽

10.1254/jjp.29.203 ◽

1979 ◽

Vol 29 (2) ◽

pp. 203-209 ◽

Cited By ~ 3

Author(s):

Masakatsu TAKAHASHI ◽

Hiroshi KANETO ◽

Eiko UENO ◽

Joe WATANABE ◽

Masao KOIDA ◽

...

Keyword(s):

Receptor Binding ◽

Opiate Receptor ◽

Binding Activity ◽

Methionine Enkephalin ◽

Receptor Binding Activity ◽

Brain Factor

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Estrophilin immunoreactivity versus estrogen receptor binding activity in meningiomas: Evidence for multiple estrogen binding sites

Surgical Neurology ◽

10.1016/0090-3019(87)90131-5 ◽

1987 ◽

Vol 28 (3) ◽

pp. 181-188 ◽

Cited By ~ 6

Author(s):

K.P. Lesch ◽

W. Schott ◽

S. Gross

Keyword(s):

Estrogen Receptor ◽

Receptor Binding ◽

Binding Sites ◽

Binding Activity ◽

Estrogen Receptor Binding ◽

Receptor Binding Activity ◽

Estrogen Binding

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6-Substituted-9-(3-formamidobenzyl)-9H-purines. Benzodiazepine receptor binding activity

Journal of Heterocyclic Chemistry ◽

10.1002/jhet.5570280444 ◽

1991 ◽

Vol 28 (4) ◽

pp. 1099-1104 ◽

Cited By ~ 2

Author(s):

James L. Kelley ◽

Ed W. Mclean ◽

Robert M. Ferris ◽

James L. Howard

Keyword(s):

Receptor Binding ◽

Benzodiazepine Receptor ◽

Binding Activity ◽

Receptor Binding Activity

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ChemInform Abstract: Novel Drimane Sesquiterpene Esters from Aspergillus ustus var. pseudodeflectus with Endothelin Receptor Binding Activity.

ChemInform ◽

10.1002/chin.199647195 ◽

2010 ◽

Vol 27 (47) ◽

pp. no-no

Author(s):

M. A. HAYES ◽

S. K. WRIGLEY ◽

I. CHETLAND ◽

E. E. REYNOLDS ◽

A. M. AINSWORTH ◽

...

Keyword(s):

Receptor Binding ◽

Binding Activity ◽

Endothelin Receptor ◽

Aspergillus Ustus ◽

Receptor Binding Activity

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Celecoxib does not induce convulsions nor does it affect GABAA receptor binding activity in the presence of new quinolones in mice

European Journal of Pharmacology ◽

10.1016/j.ejphar.2004.11.038 ◽

2005 ◽

Vol 507 (1-3) ◽

pp. 69-76 ◽

Cited By ~ 7

Author(s):

Taiji Yoshino ◽

Masahiro Noguchi ◽

Hiroko Okutsu ◽

Aishi Kimoto ◽

Masao Sasamata ◽

...

Keyword(s):

Gabaa Receptor ◽

Receptor Binding ◽

Binding Activity ◽

Receptor Binding Activity ◽

New Quinolones

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Ethanol and Fetal Nutrition Effect of Chronic Ethanol exposure on rat Placental Growth and Membrane Associated folic Acid Receptor Binding Activity

Journal of Pediatric Gastroenterology and Nutrition ◽

10.1097/00005176-198508000-00026 ◽

1985 ◽

Vol 4 (4) ◽

pp. 645-649 ◽

Cited By ~ 27

Author(s):

Stanely E. Fisher ◽

Laura S. Inselman ◽

Lynn Duffy ◽

Mark Atkinson ◽

Hyacinth Spencer ◽

...

Keyword(s):

Folic Acid ◽

Receptor Binding ◽

Binding Activity ◽

Ethanol Exposure ◽

Chronic Ethanol ◽

Acid Receptor ◽

Chronic Ethanol Exposure ◽

Receptor Binding Activity ◽

Fetal Nutrition ◽

Folic Acid Receptor

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Structural studies of Drosophila short neuropeptide F: Occurrence and receptor binding activity

Peptides ◽

10.1016/j.peptides.2005.06.029 ◽

2006 ◽

Vol 27 (3) ◽

pp. 575-582 ◽

Cited By ~ 35

Author(s):

Stephen F. Garczynski ◽

Mark R. Brown ◽

Joe W. Crim

Keyword(s):

Receptor Binding ◽

Binding Activity ◽

Structural Studies ◽

Receptor Binding Activity ◽

Neuropeptide F

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Amino acid substitution at position 226 of the hemagglutinin molecule of influenza (H1N1) virus affects receptor binding activity but not fusion activity

Virology ◽

10.1016/0042-6822(88)90048-7 ◽

1988 ◽

Vol 167 (1) ◽

pp. 8-14 ◽

Cited By ~ 17

Author(s):

Eri Nobusawa ◽

Katsuhisa Nakajima

Keyword(s):

Amino Acid ◽

Receptor Binding ◽

Amino Acid Substitution ◽

H1n1 Virus ◽

Binding Activity ◽

Fusion Activity ◽

Receptor Binding Activity ◽

Influenza H1n1

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Comparison of particulate guanylate cyclase in cells with and without atrial natriuretic peptide receptor binding activity

Molecular and Cellular Biochemistry ◽

10.1007/bf00225217 ◽

1989 ◽

Vol 90 (1) ◽

Cited By ~ 3

Author(s):

ScottA. Waldman ◽

DaleC. Leitman ◽

LingY. Chang ◽

Ferid Murad

Keyword(s):

Atrial Natriuretic Peptide ◽

Natriuretic Peptide ◽

Receptor Binding ◽

Guanylate Cyclase ◽

Binding Activity ◽

Natriuretic Peptide Receptor ◽

Peptide Receptor ◽

Receptor Binding Activity ◽

Atrial Natriuretic Peptide Receptor ◽

In Cells

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