Synthesis and SAR studies of 1,4-diazabicyclo[3.2.2]nonane phenyl carbamates – subtype selective, high affinity α7 nicotinic acetylcholine receptor agonists

2009 ◽  
Vol 19 (16) ◽  
pp. 4747-4751 ◽  
Author(s):  
Christopher J. O’Donnell ◽  
Langu Peng ◽  
Brian T. O’Neill ◽  
Eric P. Arnold ◽  
Robert J. Mather ◽  
...  
Keyword(s):  
Acetylcholine Receptor ◽  
Nicotinic Acetylcholine Receptor ◽  
Α7 Nicotinic Acetylcholine Receptor ◽  
Nicotinic Acetylcholine ◽  
Receptor Agonists ◽  
High Affinity ◽  
Sar Studies ◽  
Subtype Selective

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Vol 160 (2) ◽  
pp. 322-333 ◽  
Author(s):  
Susanne A Snoek ◽  
Marleen I Verstege ◽  
Esmerij P van der Zanden ◽  
Nigel Deeks ◽  
David C Bulmer ◽  
...  
Keyword(s):  
Acetylcholine Receptor ◽  
Nicotinic Acetylcholine Receptor ◽  
Experimental Colitis ◽  
Α7 Nicotinic Acetylcholine Receptor ◽  
Nicotinic Acetylcholine ◽  
Receptor Agonists

Gamma-lactams—A novel scaffold for highly potent and selective α7 nicotinic acetylcholine receptor agonists

2009 ◽  
Vol 19 (5) ◽  
pp. 1287-1291 ◽  
Author(s):  
Albert Enz ◽  
Dominik Feuerbach ◽  
Mathias U. Frederiksen ◽  
Conrad Gentsch ◽  
Konstanze Hurth ◽  
...  
Keyword(s):  
Acetylcholine Receptor ◽  
Nicotinic Acetylcholine Receptor ◽  
Α7 Nicotinic Acetylcholine Receptor ◽  
Nicotinic Acetylcholine ◽  
Receptor Agonists ◽  
Novel Scaffold

scholarly journals β-Amyloid1–42Binds to α7 Nicotinic Acetylcholine Receptor with High Affinity

2000 ◽  
Vol 275 (8) ◽  
pp. 5626-5632 ◽  
Author(s):  
Hoau-Yan Wang ◽  
Daniel H. S. Lee ◽  
Michael R. D'Andrea ◽  
Per A. Peterson ◽  
Richard P. Shank ◽  
...  
Keyword(s):  
Acetylcholine Receptor ◽  
Nicotinic Acetylcholine Receptor ◽  
Α7 Nicotinic Acetylcholine Receptor ◽  
Nicotinic Acetylcholine ◽  
High Affinity
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