scholarly journals In Vivo Evaluation of α7 Nicotinic Acetylcholine Receptor Agonists [11C]A-582941 and [11C]A-844606 in Mice and Conscious Monkeys

PLoS ONE ◽  
2010 ◽  
Vol 5 (2) ◽  
pp. e8961 ◽  
Author(s):  
Jun Toyohara ◽  
Kiichi Ishiwata ◽  
Muneyuki Sakata ◽  
Jin Wu ◽  
Shingo Nishiyama ◽  
...  
Keyword(s):  
Acetylcholine Receptor ◽  
Nicotinic Acetylcholine Receptor ◽  
Α7 Nicotinic Acetylcholine Receptor ◽  
In Vivo Evaluation ◽  
Nicotinic Acetylcholine ◽  
Receptor Agonists

Radiochemical synthesis and in vivo evaluation of [18F]AZ11637326: An agonist probe for the α7 nicotinic acetylcholine receptor

2013 ◽  
Vol 40 (6) ◽  
pp. 731-739 ◽  
Author(s):  
Hayden T. Ravert ◽  
Peter Dorff ◽  
Catherine A. Foss ◽  
Ronnie C. Mease ◽  
Hong Fan ◽  
...  
Keyword(s):  
Acetylcholine Receptor ◽  
Nicotinic Acetylcholine Receptor ◽  
Α7 Nicotinic Acetylcholine Receptor ◽  
In Vivo Evaluation ◽  
Nicotinic Acetylcholine ◽  
Radiochemical Synthesis

scholarly journals Selective α7 nicotinic acetylcholine receptor agonists worsen disease in experimental colitis

2010 ◽  
Vol 160 (2) ◽  
pp. 322-333 ◽  
Author(s):  
Susanne A Snoek ◽  
Marleen I Verstege ◽  
Esmerij P van der Zanden ◽  
Nigel Deeks ◽  
David C Bulmer ◽  
...  
Keyword(s):  
Acetylcholine Receptor ◽  
Nicotinic Acetylcholine Receptor ◽  
Experimental Colitis ◽  
Α7 Nicotinic Acetylcholine Receptor ◽  
Nicotinic Acetylcholine ◽  
Receptor Agonists

Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide as an agonist of the α7 nicotinic acetylcholine receptor: In vitro and in vivo activity

2008 ◽  
Vol 18 (12) ◽  
pp. 3611-3615 ◽  
Author(s):  
Brad A. Acker ◽  
E. Jon Jacobsen ◽  
Bruce N. Rogers ◽  
Donn G. Wishka ◽  
Steven C. Reitz ◽  
...  
Keyword(s):  
Acetylcholine Receptor ◽  
Nicotinic Acetylcholine Receptor ◽  
Α7 Nicotinic Acetylcholine Receptor ◽  
Nicotinic Acetylcholine

Effects of α7 nicotinic acetylcholine receptor agonists on antipsychotic efficacy in a preclinical mouse model of psychosis

2011 ◽  
Vol 220 (4) ◽  
pp. 823-833 ◽  
Author(s):  
Kathy L. Kohlhaas ◽  
Robert S. Bitner ◽  
Murali Gopalakrishnan ◽  
Lynne E. Rueter
Keyword(s):  
Mouse Model ◽  
Acetylcholine Receptor ◽  
Nicotinic Acetylcholine Receptor ◽  
Α7 Nicotinic Acetylcholine Receptor ◽  
Nicotinic Acetylcholine ◽  
Receptor Agonists ◽  
Antipsychotic Efficacy

scholarly journals Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with α7 nicotinic acetylcholine receptor agonists

2015 ◽  
Vol 97 (4) ◽  
pp. 454-462 ◽  
Author(s):  
S. Sakura Minami ◽  
Vivian Shen ◽  
David Le ◽  
Grietje Krabbe ◽  
Rustam Asgarov ◽  
...  
Keyword(s):  
Acetylcholine Receptor ◽  
Nicotinic Acetylcholine Receptor ◽  
Α7 Nicotinic Acetylcholine Receptor ◽  
Behavioral Deficits ◽  
Nicotinic Acetylcholine ◽  
Receptor Agonists ◽  
Deficient Mice

scholarly journals Therapeutic potential of α7 nicotinic acetylcholine receptor agonists to combat obesity, diabetes, and inflammation

2020 ◽  
Vol 21 (4) ◽  
pp. 431-447
Author(s):  
Han Xie ◽  
Natesh Yepuri ◽  
Qinghe Meng ◽  
Ravi Dhawan ◽  
Colin A. Leech ◽  
...  
Keyword(s):  
Acetylcholine Receptor ◽  
Nicotinic Acetylcholine Receptor ◽  
Therapeutic Potential ◽  
Α7 Nicotinic Acetylcholine Receptor ◽  
Nicotinic Acetylcholine ◽  
Receptor Agonists

Synthesis and SAR studies of 1,4-diazabicyclo[3.2.2]nonane phenyl carbamates – subtype selective, high affinity α7 nicotinic acetylcholine receptor agonists

2009 ◽  
Vol 19 (16) ◽  
pp. 4747-4751 ◽  
Author(s):  
Christopher J. O’Donnell ◽  
Langu Peng ◽  
Brian T. O’Neill ◽  
Eric P. Arnold ◽  
Robert J. Mather ◽  
...  
Keyword(s):  
Acetylcholine Receptor ◽  
Nicotinic Acetylcholine Receptor ◽  
Α7 Nicotinic Acetylcholine Receptor ◽  
Nicotinic Acetylcholine ◽  
Receptor Agonists ◽  
High Affinity ◽  
Sar Studies ◽  
Subtype Selective
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