Design, synthesis and biological evaluation of new potent and highly selective ROS1-tyrosine kinase inhibitor

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2009.06.066 ◽

2009 ◽

Vol 19 (16) ◽

pp. 4720-4723 ◽

Author(s):

Byung Sun Park ◽

Ibrahim M. El-Deeb ◽

Kyung Ho Yoo ◽

Chang-Hyun Oh ◽

Seung Joo Cho ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Kinase Inhibitor ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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WITHDRAWN: Design, synthesis and biological evaluation of 3-substituted-4-anilinequinoline as EGFR tyrosine kinase inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2012.10.030 ◽

2012 ◽

Author(s):

Yongjun Mao ◽

Kai Xie ◽

Wenxiu Zhu ◽

Jianfeng Li ◽

Hua Xie ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Egfr Tyrosine Kinase ◽

Egfr Tyrosine Kinase Inhibitors ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of novel pyrimidine, 3-cyanopyridine and m-amino-N-phenylbenzamide based monocyclic EGFR tyrosine kinase inhibitors

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2013.03.053 ◽

2013 ◽

Vol 21 (11) ◽

pp. 3090-3104 ◽

Author(s):

Yongjun Mao ◽

Wenxiu Zhu ◽

Xiaoguang Kong ◽

Zhen Wang ◽

Hua Xie ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Egfr Tyrosine Kinase ◽

Egfr Tyrosine Kinase Inhibitors ◽

Synthesis And Biological Evaluation

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The design, synthesis, and biological evaluation of potent receptor tyrosine kinase inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2012.06.029 ◽

2012 ◽

Vol 22 (15) ◽

pp. 4979-4985 ◽

Author(s):

Moon H. Kim ◽

Amy Lew Tsuhako ◽

Erick W. Co ◽

Dana T. Aftab ◽

Frauke Bentzien ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Receptor Tyrosine Kinase Inhibitors

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Design, synthesis, and biological evaluation of 4-phenoxyquinoline derivatives as potent c-Met kinase inhibitor

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2019.126666 ◽

2019 ◽

Vol 29 (23) ◽

pp. 126666 ◽

Author(s):

Yifeng Yang ◽

Yingxiu Li ◽

Yunlei Hou ◽

Mingze Qin ◽

Ping Gong ◽

...

Keyword(s):

Kinase Inhibitor ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Discovery of a Selective Kinase Inhibitor (TAK-632) Targeting Pan-RAF Inhibition: Design, Synthesis, and Biological Evaluation ofC-7-Substituted 1,3-Benzothiazole Derivatives

Journal of Medicinal Chemistry ◽

10.1021/jm400778d ◽

2013 ◽

Vol 56 (16) ◽

pp. 6478-6494 ◽

Author(s):

Masanori Okaniwa ◽

Masaaki Hirose ◽

Takeo Arita ◽

Masato Yabuki ◽

Akito Nakamura ◽

...

Keyword(s):

Kinase Inhibitor ◽

Biological Evaluation ◽

Design Synthesis ◽

Benzothiazole Derivatives ◽

Selective Kinase Inhibitor ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of substituted pyrrolo[2,3-d]pyrimidines as multiple receptor tyrosine kinase inhibitors and antiangiogenic agents

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2008.04.019 ◽

2008 ◽

Vol 16 (10) ◽

pp. 5514-5528 ◽

Author(s):

Aleem Gangjee ◽

Ojas A. Namjoshi ◽

Jianming Yu ◽

Michael A. Ihnat ◽

Jessica E. Thorpe ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitors ◽

Biological Evaluation ◽

Antiangiogenic Agents ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Multiple Receptor ◽

Receptor Tyrosine Kinase Inhibitors

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Design, synthesis, and biological evaluation of novel 3-pyrrolo[b]cyclohexylene-2-dihydroindolinone derivatives as potent receptor tyrosine kinase inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2013.08.037 ◽

2013 ◽

Vol 23 (20) ◽

pp. 5630-5633 ◽

Author(s):

Lei Ding ◽

Feng Tang ◽

Wei Huang ◽

Qiu Jin ◽

Han Shen ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Receptor Tyrosine Kinase Inhibitors

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Part-1: Design, synthesis and biological evaluation of novel bromo-pyrimidine analogs as tyrosine kinase inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2016.04.056 ◽

2016 ◽

Vol 119 ◽

pp. 70-82 ◽

Author(s):

Chandrashekar Suradhenupura Munikrishnappa ◽

Sangamesh B. Puranik ◽

G.V. Suresh Kumar ◽

Y. Rajendra Prasad

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Pyrimidine Analogs ◽

Synthesis And Biological Evaluation

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Design, synthesis, and biological evaluation of 2,6,7-substituted pyrrolo[2,3-d]pyrimidines as cyclin dependent kinase inhibitor in pancreatic cancer cells

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2020.127725 ◽

2021 ◽

Vol 33 ◽

pp. 127725

Author(s):

Xingpeng Shi ◽

Yanni Quan ◽

Yixuan Wang ◽

Ying Wang ◽

Yanping Li

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Kinase Inhibitor ◽

Biological Evaluation ◽

Cyclin Dependent Kinase ◽

Design Synthesis ◽

Cyclin Dependent Kinase Inhibitor ◽

Pancreatic Cancer Cells ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of pyrimidine-based derivatives as VEGFR-2 tyrosine kinase inhibitors

Bioorganic Chemistry ◽

10.1016/j.bioorg.2018.04.005 ◽

2018 ◽

Vol 78 ◽

pp. 393-405 ◽

Author(s):

Wuji Sun ◽

Shengquan Hu ◽

Shubiao Fang ◽

Hong Yan

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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