Design and synthesis of a novel series of (1′ S ,2 R ,4′ S )-3 H -4′-azaspiro[benzo[4,5]imidazo[2,1- b ]oxazole-2,2′-bicyclo[2.2.2]octanes] with high affinity for the α7 neuronal nicotinic receptor

2017 ◽  
Vol 27 (22) ◽  
pp. 5002-5005
Author(s):  
James Cook ◽  
F. Christopher Zusi ◽  
Matthew D. Hill ◽  
Haiquan Fang ◽  
Bradley Pearce ◽  
...  
Keyword(s):  
Nicotinic Receptor ◽  
Neuronal Nicotinic Receptor ◽  
Design And Synthesis ◽  
High Affinity

Structural aspects of high affinity ligands for the α4β2 neuronal nicotinic receptor

2000 ◽  
Vol 74 (2-3) ◽  
pp. 115-123 ◽  
Author(s):  
Michael J. Dart ◽  
James T. Wasicak ◽  
Keith B. Ryther ◽  
Michael R. Schrimpf ◽  
Ki H. Kim ◽  
...  
Keyword(s):  
Nicotinic Receptor ◽  
Affinity Ligands ◽  
Neuronal Nicotinic Receptor ◽  
High Affinity ◽  
Structural Aspects

Receptor Binding Thermodynamics at the Neuronal Nicotinic Receptor

2004 ◽  
Vol 4 (3) ◽  
pp. 361-368 ◽  
Author(s):  
P.A. Borea ◽  
K. Varani ◽  
S.G., S. Merighi ◽  
A.D. Piaz ◽  
P. Gilli ◽  
...  
Keyword(s):  
Receptor Binding ◽  
Nicotinic Receptor ◽  
Neuronal Nicotinic Receptor ◽  
Binding Thermodynamics

Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor

Nature ◽  
1991 ◽  
Vol 353 (6347) ◽  
pp. 846-849 ◽  
Author(s):  
F. Revah ◽  
D. Bertrand ◽  
J.-L Galzi ◽  
A. Devillers-Thiéry ◽  
C. Mulle ◽  
...  
Keyword(s):  
Nicotinic Receptor ◽  
Neuronal Nicotinic Receptor

Design and Synthesis of a Series of Non-Peptide High-Affinity Human Corticotropin-Releasing Factor1Receptor Antagonists

1996 ◽  
Vol 39 (22) ◽  
pp. 4358-4360 ◽  
Author(s):  
Chen ◽  
Raymond Dagnino ◽  
Errol B. De Souza ◽  
Dimitri E. Grigoriadis ◽  
Charles Q. Huang ◽  
...  
Keyword(s):  
Design And Synthesis ◽  
High Affinity

Upregulation of Neuronal Nicotinic Receptor Subunits α4,β2,and α7 in Transgenic Mice Overexpressing Human Acetylcholinesterase

2002 ◽  
Vol 18 (3) ◽  
pp. 211-222 ◽  
Author(s):  
Marie M. Svedberg ◽  
Anne-Lie Svensson ◽  
Mary Johnson ◽  
Mandy Lee ◽  
Osnat Cohen ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Nicotinic Receptor ◽  
Neuronal Nicotinic Receptor

Reduced antinociception in mice lacking neuronal nicotinic receptor subunits

Nature ◽  
10.1038/19756 ◽  
1999 ◽  
Vol 398 (6730) ◽  
pp. 805-810 ◽  
Author(s):  
Lisa M. Marubio ◽  
Maria del Mar Arroyo-Jimenez ◽  
Matilde Cordero-Erausquin ◽  
Clément Léna ◽  
Nicolas Le Novère ◽  
...  
Keyword(s):  
Nicotinic Receptor ◽  
Neuronal Nicotinic Receptor
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