[3H]A-585539 [(1S,4S)-2,2-Dimethyl-5-(6-phenylpyridazin-3-yl)-5-aza-2-azoniabicyclo[2.2.1]heptane], a Novel High-Affinity α7 Neuronal Nicotinic Receptor Agonist: Radioligand Binding Characterization to Rat and Human Brain

2007 ◽  
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Author(s):  
David J. Anderson ◽  
William Bunnelle ◽  
Bruce Surber ◽  
Jia Du ◽  
Carol Surowy ◽  
...  
Keyword(s):  
Human Brain ◽  
Nicotinic Receptor ◽  
Receptor Agonist ◽  
Radioligand Binding ◽  
Neuronal Nicotinic Receptor ◽  
High Affinity

In vitro binding characteristics of [3H]AZ11637326, a novel α7-selective neuronal nicotinic receptor agonist radioligand

2010 ◽  
Vol 645 (1-3) ◽  
pp. 63-69 ◽  
Author(s):  
John C. Gordon ◽  
Eifion Phillips ◽  
David A. Gurley ◽  
J. Richard Heys ◽  
Lois Ann Lazor ◽  
...  
Keyword(s):  
Nicotinic Receptor ◽  
Receptor Agonist ◽  
Binding Characteristics ◽  
Neuronal Nicotinic Receptor ◽  
In Vitro Binding ◽  
Vitro Binding

Efficacy and safety of the α4β2 neuronal nicotinic receptor agonist ABT-894 in patients with diabetic peripheral neuropathic pain

Pain ◽  
2012 ◽  
Vol 153 (4) ◽  
pp. 862-868 ◽  
Author(s):  
Michael C. Rowbotham ◽  
Armen Arslanian ◽  
Wolfram Nothaft ◽  
Rachel W. Duan ◽  
Andrea E. Best ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Nicotinic Receptor ◽  
Receptor Agonist ◽  
Efficacy And Safety ◽  
Peripheral Neuropathic Pain ◽  
Neuronal Nicotinic Receptor
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