scholarly journals Eosinophil chemotactic factor-L (ECF-L) enhances osteoclast formation by increasing in osteoclast precursors expression of LFA-1 and ICAM-1

Bone ◽  
2007 ◽  
Vol 40 (2) ◽  
pp. 316-322 ◽  
Author(s):  
Veronica Garcia-Palacios ◽  
Ho Yeon Chung ◽  
Sun Jin Choi ◽  
Aliye Sarmasik ◽  
Noriyoshi Kurihara ◽  
...  
Keyword(s):  
Osteoclast Formation ◽  
Chemotactic Factor ◽  
Osteoclast Precursors ◽  
Eosinophil Chemotactic Factor

scholarly journals Biological Effects of β-Glucans on Osteoclastogenesis

Molecules ◽  
2021 ◽  
Vol 26 (7) ◽  
pp. 1982
Author(s):  
Wataru Ariyoshi ◽  
Shiika Hara ◽  
Ayaka Koga ◽  
Yoshie Nagai-Yoshioka ◽  
Ryota Yamasaki
Keyword(s):  
Bone Resorption ◽  
Bone Marrow Cells ◽  
Biological Effects ◽  
Osteoclast Differentiation ◽  
Treatment Strategies ◽  
Alcaligenes Faecalis ◽  
Osteoclast Formation ◽  
Osteoclast Precursors

Although the anti-tumor and anti-infective properties of β-glucans have been well-discussed, their role in bone metabolism has not been reviewed so far. This review discusses the biological effects of β-glucans on bone metabolisms, especially on bone-resorbing osteoclasts, which are differentiated from hematopoietic precursors. Multiple immunoreceptors that can recognize β-glucans were reported to be expressed in osteoclast precursors. Coordinated co-stimulatory signals mediated by these immunoreceptors are important for the regulation of osteoclastogenesis and bone remodeling. Curdlan from the bacterium Alcaligenes faecalis negatively regulates osteoclast differentiation in vitro by affecting both the osteoclast precursors and osteoclast-supporting cells. We also showed that laminarin, lichenan, and glucan from baker’s yeast, as well as β-1,3-glucan from Euglema gracilisas, inhibit the osteoclast formation in bone marrow cells. Consistent with these findings, systemic and local administration of β-glucan derived from Aureobasidium pullulans and Saccharomyces cerevisiae suppressed bone resorption in vivo. However, zymosan derived from S. cerevisiae stimulated the bone resorption activity and is widely used to induce arthritis in animal models. Additional research concerning the relationship between the molecular structure of β-glucan and its effect on osteoclastic bone resorption will be beneficial for the development of novel treatment strategies for bone-related diseases.

DEMONSTRATION OF EOSINOPHIL CHEMOTACTIC FACTOR IN THE BLISTER FLUID OF PATIENT WITH INCONTINENTIA PIGMENTI

1985 ◽  
Vol 12 (4) ◽  
pp. 363-368 ◽  
Author(s):  
Shingo Tsuda ◽  
Mitsunari Higuchi ◽  
Mikio Ichiki ◽  
Yoichiro Sasai
Keyword(s):  
Chemotactic Factor ◽  
Incontinentia Pigmenti ◽  
Blister Fluid ◽  
Eosinophil Chemotactic Factor

Visualization of eosinophil chemotactic factor in abomasal tissue of cattle by immunoperoxidase staining during Ostertagia ostertagi infection

1989 ◽  
Vol 31 (1) ◽  
pp. 49-56 ◽  
Author(s):  
P.H. Klesius ◽  
T.G. Snider ◽  
L.W. Horton ◽  
C.H. Crowder
Keyword(s):  
Chemotactic Factor ◽  
Immunoperoxidase Staining ◽  
Ostertagia Ostertagi ◽  
Eosinophil Chemotactic Factor

scholarly journals Ontogeny of the Production of an Estrogen-Regulated Eosinophil Chemotactic Factor in the Rat Uterus1

1991 ◽  
Vol 45 (6) ◽  
pp. 818-823 ◽  
Author(s):  
Maria C. Leiva ◽  
Qin Xu ◽  
Matthew Galman ◽  
C. Richard Lyttle
Keyword(s):  
Chemotactic Factor ◽  
Eosinophil Chemotactic Factor

Estrogen Regulation of an Eosinophil Chemotactic Factor in the Immature Rat Uterus*

Endocrinology ◽  
1989 ◽  
Vol 125 (6) ◽  
pp. 3022-3027 ◽  
Author(s):  
YON H. LEE ◽  
ROBERT S. HOWE ◽  
SHING-JIA SHA ◽  
CORY TEUSCHER ◽  
DANIEL M. SHEEHAN ◽  
...  
Keyword(s):  
Chemotactic Factor ◽  
Rat Uterus ◽  
Estrogen Regulation ◽  
Immature Rat ◽  
Eosinophil Chemotactic Factor

IL-4 inhibits TNF-α-mediated osteoclast formation by inhibition of RANKL expression in TNF-α-activated stromal cells and direct inhibition of TNF-α-activated osteoclast precursors via a T-cell-independent mechanism in vivo

Bone ◽  
2012 ◽  
Vol 51 (4) ◽  
pp. 771-780 ◽  
Author(s):  
Toshiya Fujii ◽  
Hideki Kitaura ◽  
Keisuke Kimura ◽  
Zaki Weli Hakami ◽  
Teruko Takano-Yamamoto
Keyword(s):  
T Cell ◽  
Stromal Cells ◽  
Osteoclast Formation ◽  
Rankl Expression ◽  
Direct Inhibition ◽  
Osteoclast Precursors ◽  
Tnf Α ◽  
Independent Mechanism
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