Risk for developing epilepsy and epileptiform discharges on EEG in patients with febrile seizures

2013 ◽  
Vol 35 (4) ◽  
pp. 307-311 ◽  
Author(s):  
Saet Byul Wo ◽  
Jun Hwa Lee ◽  
Yong Ju Lee ◽  
Tae-Jung Sung ◽  
Kon Hee Lee ◽  
...  
Author(s):  
C Dash ◽  
BJ Mischuk ◽  
S Almubarak ◽  
F Moien-Afshari

Background: Psychiatrists commonly use electroencephalogram (EEG) to rule out epilepsy as a cause of psychiatric symptoms. A large number of these studies are normal. Our study aims to identify the predictive factors of an EEG with epileptiform activity in these patients. Methods: We performed a retrospective study of the EEG results and chart reviews of the 208 psychiatric patients at Royal University Hospital in Saskatoon, Saskatchewan from 2013-2015. The EEG results were correlated with several factors known to increase the probability of an abnormal recording including history of seizures, previously abnormal EEGs, imaging abnormalities, medications known to cause epileptiform discharges, electroconvulsive therapy, prematurity, brain infection, childhood febrile seizures, head trauma, and family history. Results: Of the 208 EEGs performed, 176 (84%) were normal (77%) or essentially normal (7%). Epileptiform activity was found in 13 EEGs (6.3%), of which 9 (4.3%) had a previous EEG with epileptiform activity. Focal slowing appeared in 12 EEGs (5.8%), two of which had previous abnormal EEGs. Generalized slowing was found in 7 EEGs (3.4%). Conclusions: We conclude that the majority of EEGs in patients with psychiatric manifestations are normal. The most predictive factor for epileptiform activity in this population is a previous EEG with epileptiform discharges. Other predictive factors are under review.


Author(s):  
AN Datta ◽  
L Wallbank ◽  
J Micallef ◽  
PK Wong

Background: Pediatric occipital epileptiform discharges (OEDS) occur in various clinical settings, including benign and symptomatic epilepsies. The study objective is to determine electro-clinical predictors for aetiology and prognosis in children with OEDs. Methods: 205 patients with OEDs were classified into seizure groups: symptomatic (n=98), idiopathic focal (IF) (n=57), idiopathic generalized (IG) (n=18), no-seizures (n=27) and febrile seizures (n=5). Results: The median age of seizure onset was 3 years (range: 0-19). There was more EEG background slowing (P<0.05) in the symptomatic; photosensitivity (P<0.0001) and GSW (P<0.0001) in IG; and presence of consistent EEG spike dipole in IF group. The symptomatic had more DD (P< 0.0001), autism (P <0.019), and school difficulties (P<0.001) than the IF and IG groups, but not different from the no-seizure group. Conclusions: OEDs with consistent dipole spike is predictive of IF epilepsy. In contrast to frontal and temporal lobe epilepsy, only 30% with symptomatic epilepsy had occipital-predominant neuro-imaging abnormalities. Notably, neuro-psychiatric co-morbidities were similar between the symptomatic and no-seizure group.


2018 ◽  
Vol 33 (12) ◽  
pp. 772-775
Author(s):  
Alja Kavčič ◽  
Zvonka Rener-Primec

The predictive value of epileptiform discharges for subsequent epilepsy after febrile seizures was studied in 140 children: 72 children (51%) had simple febrile seizures and 68 children (49%) had complex febrile seizures. Electroencephalography (EEG) was performed in 103 children (74%), it was normal in 66 (47%) and with epileptiform patterns in 37 patients (26%). At follow-up in 2017, 10 children developed epilepsy, 1 had a single epileptic seizure, 9 of them had epileptiform EEGs. Of the patients with normal EEGs after complex febrile seizures, none developed epilepsy, and 92% of patients with normal EEGs after recurrent febrile seizures did not develop epilepsy. Therefore, patients with normal EEGs were unlikely to develop epilepsy. Fifteen percent of patients with complex and 31% of patients with recurrent febrile seizures and epileptiform EEGs developed epileptic seizures. The positive predictive value of epileptiform discharges was low in complex and twice as high in recurrent febrile seizures.


2020 ◽  
Vol 13 (2) ◽  
pp. 28-31
Author(s):  
Venugopal Raju ◽  
◽  
Balabaskar Reddy ◽  
Keyword(s):  

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