Signalling pathways in the nitric oxide donor-induced dopamine release in the striatum of freely moving rats: evidence that exogenous nitric oxide promotes Ca2+ entry through store-operated channels

2004 ◽  
Vol 1023 (2) ◽  
pp. 243-252 ◽  
Author(s):  
Gaia Rocchitta ◽  
Rossana Migheli ◽  
Maria P. Mura ◽  
Giovanni Esposito ◽  
Maria S. Desole ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Dopamine Release ◽  
Nitric Oxide Donor ◽  
Signalling Pathways ◽  
Freely Moving Rats ◽  
Freely Moving ◽  
Exogenous Nitric Oxide

scholarly journals A study on the role of nitric oxide and iron in 3-morpholino-sydnonimine-induced increases in dopamine release in the striatum of freely moving rats

2001 ◽  
Vol 134 (2) ◽  
pp. 275-282 ◽  
Author(s):  
Pier Andrea Serra ◽  
Gaia Rocchitta ◽  
Giovanni Esposito ◽  
M Rosaria Delogu ◽  
Rossana Migheli ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Dopamine Release ◽  
Freely Moving Rats ◽  
Freely Moving

scholarly journals Analysis of 3-morpholinosydnonimine and sodium nitroprusside effects on dopamine release in the striatum of freely moving rats: role of nitric oxide, iron and ascorbic acid

2000 ◽  
Vol 131 (4) ◽  
pp. 836-842 ◽  
Author(s):  
Pier Andrea Serra ◽  
Giovanni Esposito ◽  
M Rosaria Delogu ◽  
Rossana Migheli ◽  
Gaia Rocchitta ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Ascorbic Acid ◽  
Sodium Nitroprusside ◽  
Dopamine Release ◽  
Freely Moving Rats ◽  
Freely Moving

Signaling pathways in the nitric oxide and iron-induced dopamine release in the striatum of freely moving rats: Role of extracellular Ca2+ and L-type Ca2+ channels

2005 ◽  
Vol 1047 (1) ◽  
pp. 18-29 ◽  
Author(s):  
Gaia Rocchitta ◽  
Rossana Migheli ◽  
Maria P. Mura ◽  
Giuseppe Grella ◽  
Giovanni Esposito ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Signaling Pathways ◽  
Dopamine Release ◽  
Freely Moving Rats ◽  
Freely Moving ◽  
Ca2 Channels

Myocardial relaxant effect of exogenous nitric oxide in isolated ejecting hearts

1994 ◽  
Vol 266 (5) ◽  
pp. H1699-H1705 ◽  
Author(s):  
R. Grocott-Mason ◽  
S. Fort ◽  
M. J. Lewis ◽  
A. M. Shah
Keyword(s):  
Nitric Oxide ◽  
Sodium Nitroprusside ◽  
Coronary Flow ◽  
Systolic Function ◽  
Myocardial Contraction ◽  
Left Ventricular ◽  
Nitric Oxide Donor ◽  
Vasodilator Activity ◽  
Exogenous Nitric Oxide ◽  
Whole Heart

In isolated myocytes and papillary muscles, both nitric oxide, acting through guanosine 3',5'-cyclic monophosphate (cGMP), and cGMP analogues exert a novel effect on myocardial contraction, influencing mainly the onset of relaxation. We studied the effect of the exogenous nitric oxide donor, sodium nitroprusside (0.1-10 microM), in isolated ejecting guinea pig hearts at constant filling pressure, afterload, and heart rate to identify its direct myocardial effects in the whole heart. Sodium nitroprusside induced concentration-dependent increases in coronary flow as well as premature and faster early left ventricular (LV) pressure decline, but did not change end-diastolic or peak LV pressure or peak rate of rise of LV pressure. There was no correlation between changes in coronary flow and LV pressure decline. Sodium nitroprusside effects were inhibited by hemoglobin, which inactivates nitric oxide. The cGMP-independent vasodilator nicardipine also increased coronary flow but did not influence early LV pressure fall. Thus exogenous nitric oxide exerts novel direct myocardial relaxant effects in the isolated ejecting heart, independent of its known vasodilator activity, and without compromising systolic function.

Effects of idazoxan on dopamine release in the prefrontal cortex of freely moving rats

1998 ◽  
Vol 343 (2-3) ◽  
pp. 165-170 ◽  
Author(s):  
Machiko Matsumoto ◽  
Mitsuhiro Yoshioka ◽  
Hiroko Togashi ◽  
Kiyoshi Mori ◽  
Ken-ichi Ueno ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Dopamine Release ◽  
Freely Moving Rats ◽  
Freely Moving
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