Signaling pathways in the nitric oxide and iron-induced dopamine release in the striatum of freely moving rats: Role of extracellular Ca2+ and L-type Ca2+ channels

2005 ◽  
Vol 1047 (1) ◽  
pp. 18-29 ◽  
Author(s):  
Gaia Rocchitta ◽  
Rossana Migheli ◽  
Maria P. Mura ◽  
Giuseppe Grella ◽  
Giovanni Esposito ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Signaling Pathways ◽  
Dopamine Release ◽  
Freely Moving Rats ◽  
Freely Moving ◽  
Ca2 Channels

scholarly journals A study on the role of nitric oxide and iron in 3-morpholino-sydnonimine-induced increases in dopamine release in the striatum of freely moving rats

2001 ◽  
Vol 134 (2) ◽  
pp. 275-282 ◽  
Author(s):  
Pier Andrea Serra ◽  
Gaia Rocchitta ◽  
Giovanni Esposito ◽  
M Rosaria Delogu ◽  
Rossana Migheli ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Dopamine Release ◽  
Freely Moving Rats ◽  
Freely Moving

scholarly journals Analysis of 3-morpholinosydnonimine and sodium nitroprusside effects on dopamine release in the striatum of freely moving rats: role of nitric oxide, iron and ascorbic acid

2000 ◽  
Vol 131 (4) ◽  
pp. 836-842 ◽  
Author(s):  
Pier Andrea Serra ◽  
Giovanni Esposito ◽  
M Rosaria Delogu ◽  
Rossana Migheli ◽  
Gaia Rocchitta ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Ascorbic Acid ◽  
Sodium Nitroprusside ◽  
Dopamine Release ◽  
Freely Moving Rats ◽  
Freely Moving

scholarly journals Analysis of S-nitroso-N-acetylpenicillamine effects on dopamine release in the striatum of freely moving rats: role of endogenous ascorbic acid and oxidative stress

2001 ◽  
Vol 132 (4) ◽  
pp. 941-949 ◽  
Author(s):  
Pier Andrea Serra ◽  
Giovanni Esposito ◽  
M Rosaria Delogu ◽  
Rossana Migheli ◽  
Gaia Rocchitta ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Ascorbic Acid ◽  
Dopamine Release ◽  
Freely Moving Rats ◽  
Freely Moving ◽  
And Oxidative Stress

Regulatory role of nitric oxide over extracellular taurine in the hippocampus of freely moving rats

2004 ◽  
Vol 357 (3) ◽  
pp. 179-182 ◽  
Author(s):  
Jo Watts ◽  
Joanna Segieth ◽  
Brian Pearce ◽  
Peter S. Whitton
Keyword(s):  
Nitric Oxide ◽  
Regulatory Role ◽  
Freely Moving Rats ◽  
Freely Moving

The Signaling Pathways in Nitric Oxide Production by Neutrophils Exposed to N-nitrosodimethylamine

2018 ◽  
Vol 16 (2) ◽  
pp. 194-199
Author(s):  
Wioletta Ratajczak-Wrona ◽  
Ewa Jablonska
Keyword(s):  
Nitric Oxide ◽  
Signaling Pathways ◽  
Molecular Mechanisms ◽  
Polymorphonuclear Neutrophils ◽  
Microbial Pathogens ◽  
Human Neutrophils ◽  
No Production ◽  
Oxide Synthase ◽  
Inducible Nitric Oxide

Background: Polymorphonuclear neutrophils (PMNs) play a crucial role in the innate immune system’s response to microbial pathogens through the release of reactive nitrogen species, including Nitric Oxide (NO). </P><P> Methods: In neutrophils, NO is produced by the inducible Nitric Oxide Synthase (iNOS), which is regulated by various signaling pathways and transcription factors. N-nitrosodimethylamine (NDMA), a potential human carcinogen, affects immune cells. NDMA plays a major part in the growing incidence of cancers. Thanks to the increasing knowledge on the toxicological role of NDMA, the environmental factors that condition the exposure to this compound, especially its precursors- nitrates arouse wide concern. Results: In this article, we present a detailed summary of the molecular mechanisms of NDMA’s effect on the iNOS-dependent NO production in human neutrophils. Conclusion: This research contributes to a more complete understanding of the mechanisms that explain the changes that occur during nonspecific cellular responses to NDMA toxicity.

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