The ROCK inhibitor Y-27632 ameliorates blood-spinal cord barrier disruption by reducing tight junction protein degradation via the MYPT1-MLC2 pathway after spinal cord injury in rats

Brain Research ◽

10.1016/j.brainres.2021.147684 ◽

2021 ◽

Vol 1773 ◽

pp. 147684

Author(s):

Sheng Chang ◽

Yang Cao

Keyword(s):

Spinal Cord ◽

Spinal Cord Injury ◽

Tight Junction ◽

Protein Degradation ◽

Tight Junction Protein ◽

Rock Inhibitor ◽

Barrier Disruption ◽

Junction Protein ◽

Cord Injury ◽

Blood Spinal Cord Barrier

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Gallic acid attenuates blood spinal cord barrier disruption by inhibiting Jmjd3 expression and activation after spinal cord injury

IBRO Reports ◽

10.1016/j.ibror.2019.07.1143 ◽

2019 ◽

Vol 6 ◽

pp. S359-S360

Author(s):

Chan Sol Park ◽

Jee Youn Lee ◽

Hae Young Choi ◽

Tae Young Yune

Keyword(s):

Spinal Cord ◽

Spinal Cord Injury ◽

Gallic Acid ◽

Barrier Disruption ◽

Cord Injury ◽

Blood Spinal Cord Barrier

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Early microvascular reactions and blood–spinal cord barrier disruption are instrumental in pathophysiology of spinal cord injury and repair: novel therapeutic strategies including nanowired drug delivery to enhance neuroprotection

Journal of Neural Transmission ◽

10.1007/s00702-010-0514-4 ◽

2010 ◽

Vol 118 (1) ◽

pp. 155-176 ◽

Cited By ~ 46

Author(s):

Hari Shanker Sharma

Keyword(s):

Drug Delivery ◽

Spinal Cord ◽

Spinal Cord Injury ◽

Therapeutic Strategies ◽

Barrier Disruption ◽

Cord Injury ◽

Blood Spinal Cord Barrier ◽

Injury And Repair ◽

Novel Therapeutic Strategies ◽

Novel Therapeutic

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Propitious Therapeutic Modulators to Prevent Blood-Spinal Cord Barrier Disruption in Spinal Cord Injury

Molecular Neurobiology ◽

10.1007/s12035-016-9910-6 ◽

2016 ◽

Vol 54 (5) ◽

pp. 3578-3590 ◽

Cited By ~ 20

Author(s):

Hemant Kumar ◽

Alexander E. Ropper ◽

Soo-Hong Lee ◽

Inbo Han

Keyword(s):

Spinal Cord ◽

Spinal Cord Injury ◽

Barrier Disruption ◽

Cord Injury ◽

Blood Spinal Cord Barrier

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Role of hypoxia-induced VEGF in blood-spinal cord barrier disruption in chronic spinal cord injury

Chinese Journal of Traumatology ◽

10.1016/j.cjtee.2015.08.004 ◽

2015 ◽

Vol 18 (5) ◽

pp. 293-295 ◽

Cited By ~ 4

Author(s):

Hou-Qing Long ◽

Guang-Sheng Li ◽

Xing Cheng ◽

Jing-Hui Xu ◽

Fo-Bao Li

Keyword(s):

Spinal Cord ◽

Spinal Cord Injury ◽

Chronic Spinal Cord Injury ◽

Barrier Disruption ◽

Cord Injury ◽

Blood Spinal Cord Barrier

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Baicalin attenuates blood-spinal cord barrier disruption and apoptosis through PI3K/Akt signaling pathway after spinal cord injury

Neural Regeneration Research ◽

10.4103/1673-5374.324857 ◽

2022 ◽

Vol 17 (5) ◽

pp. 1080

Author(s):

Qian Zhang ◽

Rui Zhao ◽

Xue Wu ◽

Xue-Yuan Bi ◽

Hao Yang

Keyword(s):

Spinal Cord ◽

Spinal Cord Injury ◽

Signaling Pathway ◽

Akt Signaling ◽

Akt Signaling Pathway ◽

Barrier Disruption ◽

Cord Injury ◽

Blood Spinal Cord Barrier

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Valproic acid attenuates blood-spinal cord barrier disruption by inhibiting matrix metalloprotease-9 activity and improves functional recovery after spinal cord injury

Journal of Neurochemistry ◽

10.1111/j.1471-4159.2012.07731.x ◽

2012 ◽

Vol 121 (5) ◽

pp. 818-829 ◽

Cited By ~ 73

Author(s):

Jee Y. Lee ◽

Hwang S. Kim ◽

Hye Y. Choi ◽

Tae H. Oh ◽

Bong G. Ju ◽

...

Keyword(s):

Spinal Cord ◽

Spinal Cord Injury ◽

Valproic Acid ◽

Functional Recovery ◽

Matrix Metalloprotease ◽

Barrier Disruption ◽

Cord Injury ◽

Blood Spinal Cord Barrier

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Cordycepin-enriched WIB-801C from Cordyceps militaris improves functional recovery by attenuating blood-spinal cord barrier disruption after spinal cord injury

Journal of Ethnopharmacology ◽

10.1016/j.jep.2017.03.047 ◽

2017 ◽

Vol 203 ◽

pp. 90-100 ◽

Cited By ~ 5

Author(s):

Jee Youn Lee ◽

Hye Young Choi ◽

Hyung Hwan Baik ◽

Bong G. Ju ◽

Won-Ki Kim ◽

...

Keyword(s):

Spinal Cord ◽

Spinal Cord Injury ◽

Functional Recovery ◽

Cordyceps Militaris ◽

Barrier Disruption ◽

Cord Injury ◽

Blood Spinal Cord Barrier

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Protocatechuic acid improves functional recovery after spinal cord injury by attenuating blood-spinal cord barrier disruption and hemorrhage in rats

Neurochemistry International ◽

10.1016/j.neuint.2019.01.013 ◽

2019 ◽

Vol 124 ◽

pp. 181-192 ◽

Cited By ~ 6

Author(s):

Chan Sol Park ◽

Jee Youn Lee ◽

Hae Young Choi ◽

Bong Gun Ju ◽

Inchan Youn ◽

...

Keyword(s):

Spinal Cord ◽

Spinal Cord Injury ◽

Functional Recovery ◽

Protocatechuic Acid ◽

Barrier Disruption ◽

Cord Injury ◽

Blood Spinal Cord Barrier

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Gallic acid attenuates blood-spinal cord barrier disruption by inhibiting Jmjd3 expression and activation after spinal cord injury

10.22541/au.159318482.27554060 ◽

2020 ◽

Author(s):

Chan Sol Park ◽

Jee Lee ◽

Hae Young Choi ◽

Kwanghyun Lee ◽

Yeonju Heo ◽

...

Keyword(s):

Spinal Cord ◽

Spinal Cord Injury ◽

Gallic Acid ◽

Barrier Disruption ◽

Cord Injury ◽

Blood Spinal Cord Barrier

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Nasal epithelial barrier disruption by particulate matter ≤2.5 μm via tight junction protein degradation

Journal of Applied Toxicology ◽

10.1002/jat.3573 ◽

2017 ◽

Vol 38 (5) ◽

pp. 678-687 ◽

Cited By ~ 26

Author(s):

Renwu Zhao ◽

Zhiqiang Guo ◽

Ruxin Zhang ◽

Congrui Deng ◽

Jian Xu ◽

...

Keyword(s):

Particulate Matter ◽

Tight Junction ◽

Protein Degradation ◽

Tight Junction Protein ◽

Epithelial Barrier ◽

Barrier Disruption ◽

Junction Protein ◽

Particulate Matter 2.5

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