Effects of transcranial direct current stimulation, tDCS, of primary somatosensory cortex, S1, on vibrotactile detection and discrimination in humans

2015 ◽  
Vol 8 (2) ◽  
pp. 315
Author(s):  
Labbé S ◽  
Meftah E-M ◽  
C.E. Chapman
Keyword(s):  
Somatosensory Cortex ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Primary Somatosensory Cortex ◽  
Direct Current Stimulation

scholarly journals Polarity-Specific Cortical Effects of Transcranial Direct Current Stimulation in Primary Somatosensory Cortex of Healthy Humans

2016 ◽  
Vol 10 ◽  
Author(s):  
Robert Rehmann ◽  
Matthias Sczesny-Kaiser ◽  
Melanie Lenz ◽  
Tomasz Gucia ◽  
Annika Schliesing ◽  
...  
Keyword(s):  
Somatosensory Cortex ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Primary Somatosensory Cortex ◽  
Direct Current Stimulation ◽  
Healthy Humans

scholarly journals Effects of transcranial direct current stimulation of primary somatosensory cortex on vibrotactile detection and discrimination

2016 ◽  
Vol 115 (4) ◽  
pp. 1978-1987 ◽  
Author(s):  
Sara Labbé ◽  
El-Mehdi Meftah ◽  
C. Elaine Chapman
Keyword(s):  
Somatosensory Cortex ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Middle Finger ◽  
Primary Somatosensory Cortex ◽  
Direct Current Stimulation ◽  
Stimulus Response ◽  
Neuronal Mechanisms ◽  
Vibrotactile Perception ◽  
Stimulation Of

Anodal transcranial direct current stimulation (a-tDCS) of primary somatosensory cortex (S1) has been shown to enhance tactile spatial acuity, but there is little information as to the underlying neuronal mechanisms. We examined vibrotactile perception on the distal phalanx of the middle finger before, during, and after contralateral S1 tDCS [a-, cathodal (c)-, and sham (s)-tDCS]. The experiments tested our shift-gain hypothesis, which predicted that a-tDCS would decrease vibrotactile detection and discrimination thresholds (leftward shift of the stimulus-response function with increased gain/slope) relative to s-tDCS, whereas c-tDCS would have the opposite effects (relative to s-tDCS). The results showed that weak a-tDCS (1 mA, 20 min) led to a reduction in both vibrotactile detection and discrimination thresholds to 73–76% of baseline during the application of the stimulation in subjects categorized as responders. These effects persisted after the end of a-tDCS but were absent 30 min later. Most, but not all, subjects showed a decrease in threshold (8/12 for detection; 9/12 for discrimination). Intersubject variability was explained by a ceiling effect in the discrimination task. c-tDCS had no significant effect on either detection or discrimination threshold. Taken together, our results supported our shift-gain hypothesis for a-tDCS but not c-tDCS.

scholarly journals Immediate and after effects of transcranial direct-current stimulation in the mouse primary somatosensory cortex

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Carlos A. Sánchez-León ◽  
Isabel Cordones ◽  
Claudia Ammann ◽  
José M. Ausín ◽  
María A. Gómez-Climent ◽  
...  
Keyword(s):  
Somatosensory Cortex ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Immunohistochemical Analysis ◽  
Gamma Oscillations ◽  
Primary Somatosensory Cortex ◽  
After Effects ◽  
Direct Current Stimulation ◽  
Sensory Evoked ◽  
Cathodal Stimulation

AbstractTranscranial direct-current stimulation (tDCS) is a non-invasive brain stimulation technique consisting in the application of weak electric currents on the scalp. Although previous studies have demonstrated the clinical value of tDCS for modulating sensory, motor, and cognitive functions, there are still huge gaps in the knowledge of the underlying physiological mechanisms. To define the immediate impact as well as the after effects of tDCS on sensory processing, we first performed electrophysiological recordings in primary somatosensory cortex (S1) of alert mice during and after administration of S1-tDCS, and followed up with immunohistochemical analysis of the stimulated brain regions. During the application of cathodal and anodal transcranial currents we observed polarity-specific bidirectional changes in the N1 component of the sensory-evoked potentials (SEPs) and associated gamma oscillations. On the other hand, 20 min of cathodal stimulation produced significant after-effects including a decreased SEP amplitude for up to 30 min, a power reduction in the 20–80 Hz range and a decrease in gamma event related synchronization (ERS). In contrast, no significant changes in SEP amplitude or power analysis were observed after anodal stimulation except for a significant increase in gamma ERS after tDCS cessation. The polarity-specific differences of these after effects were corroborated by immunohistochemical analysis, which revealed an unbalance of GAD 65–67 immunoreactivity between the stimulated versus non-stimulated S1 region only after cathodal tDCS. These results highlight the differences between immediate and after effects of tDCS, as well as the asymmetric after effects induced by anodal and cathodal stimulation.

Effects of cathodal transcranial direct current stimulation to primary somatosensory cortex on short-latency afferent inhibition

Neuroreport ◽  
2015 ◽  
Vol 26 (11) ◽  
pp. 634-637 ◽  
Author(s):  
Sho Kojima ◽  
Hideaki Onishi ◽  
Shota Miyaguchi ◽  
Shinichi Kotan ◽  
Kazuhiro Sugawara ◽  
...  
Keyword(s):  
Somatosensory Cortex ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Short Latency ◽  
Primary Somatosensory Cortex ◽  
Short Latency Afferent Inhibition ◽  
Direct Current Stimulation ◽  
Afferent Inhibition

Transcranial direct current stimulation applied over the somatosensory cortex – Differential effect on low and high frequency SEPs

2006 ◽  
Vol 117 (10) ◽  
pp. 2221-2227 ◽  
Author(s):  
Anne Dieckhöfer ◽  
Till Dino Waberski ◽  
Michael Nitsche ◽  
Walter Paulus ◽  
Helmut Buchner ◽  
...  
Keyword(s):  
Somatosensory Cortex ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
High Frequency ◽  
Differential Effect ◽  
Direct Current Stimulation

P21.3 Transcranial direct current stimulation applied over the somatosensory cortex – Differential effect on low and high frequency SEPs

2006 ◽  
Vol 117 ◽  
pp. 217 ◽  
Author(s):  
R. Gobbelé ◽  
A. Dieckhöfer ◽  
M. Nitsche ◽  
W. Paulus ◽  
H. Buchner ◽  
...  
Keyword(s):  
Somatosensory Cortex ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
High Frequency ◽  
Differential Effect ◽  
Direct Current Stimulation

Modulation of the rubber hand illusion by transcranial direct current stimulation over the contralateral somatosensory cortex

2019 ◽  
Vol 131 ◽  
pp. 353-359 ◽  
Author(s):  
Hannah Hornburger ◽  
Carine Nguemeni ◽  
Thorsten Odorfer ◽  
Daniel Zeller
Keyword(s):  
Somatosensory Cortex ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Rubber Hand Illusion ◽  
Rubber Hand ◽  
Direct Current Stimulation

scholarly journals Human primary somatosensory cortex is differentially involved in vibrotaction and nociception

2017 ◽  
Vol 118 (1) ◽  
pp. 317-330 ◽  
Author(s):  
Cédric Lenoir ◽  
Gan Huang ◽  
Yves Vandermeeren ◽  
Samar Marie Hatem ◽  
André Mouraux
Keyword(s):  
Somatosensory Cortex ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Primary Somatosensory Cortex ◽  
High Definition ◽  
Somatosensory Input ◽  
Differential Involvement ◽  
Somatosensory Stimuli ◽  
Stimulation Of

The role of the primary somatosensory cortex (S1) in vibrotaction is well established. In contrast, its involvement in nociception is still debated. Here we test whether S1 is similarly involved in the processing of nonnociceptive and nociceptive somatosensory input in humans by comparing the aftereffects of high-definition transcranial direct current stimulation (HD-tDCS) of S1 on the event-related potentials (ERPs) elicited by nonnociceptive and nociceptive somatosensory stimuli delivered to the ipsilateral and contralateral hands. Cathodal HD-tDCS significantly affected the responses to nonnociceptive somatosensory stimuli delivered to the contralateral hand: both early-latency ERPs from within S1 (N20 wave elicited by transcutaneous electrical stimulation of median nerve) and late-latency ERPs elicited outside S1 (N120 wave elicited by short-lasting mechanical vibrations delivered to index fingertip, thought to originate from bilateral operculo-insular and cingulate cortices). These results support the notion that S1 constitutes an obligatory relay for the cortical processing of nonnociceptive tactile input originating from the contralateral hemibody. Contrasting with this asymmetric effect of HD-tDCS on the responses to nonnociceptive somatosensory input, HD-tDCS over the sensorimotor cortex led to a bilateral and symmetric reduction of the magnitude of the N240 wave of nociceptive laser-evoked potentials elicited by stimulation of the hand dorsum. Taken together, our results demonstrate in humans a differential involvement of S1 in vibrotaction and nociception. NEW & NOTEWORTHY Whereas the role of the primary somatosensory cortex (S1) in vibrotaction is well established, its involvement in nociception remains strongly debated. By assessing, in healthy volunteers, the effect of high-definition transcranial direct current stimulation over S1, we demonstrate a differential involvement of S1 in vibrotaction and nociception.

P101 Assymetric immediate and long-term effects induced by transcranial direct current stimulation on alert mice somatosensory cortex

2020 ◽  
Vol 131 (4) ◽  
pp. e69
Author(s):  
C.A. Sanchez Leon ◽  
I. Cordones Cano ◽  
M.D.L. Gomez Climent ◽  
A. Carretero Guillen ◽  
G. Cheron ◽  
...  
Keyword(s):  
Somatosensory Cortex ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Long Term Effects ◽  
Direct Current Stimulation
Sign in / Sign up

Export Citation Format

Share Document