Low-frequency repetitive transcranial magnetic stimulation for obsessive-compulsive disorder

2017 ◽  
Vol 10 (2) ◽  
pp. 518 ◽  
Author(s):  
A. Mantovani ◽  
H.B. Simpson ◽  
G. D'Urso ◽  
E. Santarnecchi ◽  
S. Rossi ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Obsessive Compulsive Disorder ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Low Frequency ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

scholarly journals Effectiveness of adjunctive low frequency repetitive transcranial magnetic stimulation therapy over the left dorsolateral prefrontal cortex in refractory to medical treatment patients with obsessive-compulsive disorder: A double blind, randomized clinical trial

2021 ◽  
Author(s):  
Ghazal Jahanbakhsh ◽  
Alireza Hajseyedjavadi ◽  
Mahnaz Majidi
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Medical Treatment ◽  
Obsessive Compulsive Disorder ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Intervention Group ◽  
Low Frequency ◽  
Antipsychotic Agents ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Abstract Background: Obsessive-compulsive disorder (OCD) is a common neurotic disorder, In 2018 Application of repetitive transcranial magnetic stimulation (rTMS) for treating obsessive-compulsive disorder (OCD) has been approved by the Food and Drug Administration (28), since 2020 different methods has been tested, this study was designed to evaluate the effectiveness of adjunctive low frequency repetitive transcranial magnetic stimulation over the left dorsolateral prefrontal cortex in refractory to treatment patients suffering from obsessive compulsive disorder (OCD) Methods: This clinical trial was performed on 30 patients with OCD referred from the psychiatry clinic of 22 Bahman Hospital in Qazvin province from 2018 to 2020. Patients were randomly assigned to two groups. Intervention group received rTMS treatment at 1 Hz for 20 min (1200 (pulses / day) over the left DLPFC region as adjunctive to their medical treatment for 3 times a week and for 5 weeks while the control group received only sham condition in addition to their medical treatment. All the patients filled out the Yale Brown Questionnaire (YBOCS) Before the study, after sessions 5 and 10 during treatment, at the end of the treatment and 3 to 6 months after the treatment. The results were compared between the two groups using SPSS software version 16.Results: The mean score of post-intervention Yale Brown score was significantly lower in the intervention group. (P <0.05), it was also significant by gender (females), marital status ,taking antipsychotic agents in addition to the serotonergic agents and with more treatment sessions, within 3 to 6 months after intervention. Conclusion: adjunctive low frequency (1 Hz)rtms over the left DLPFC can be effective in reducing Yale Brown score in refractory to treatment patients suffering from OCD after 15 sessions. Gender, treatment sessions, usage of antipsychotic agents as adjuvant with standard treatment regiments, and marital status were identified as predictors for response to adjunctive rTMS therapy.

scholarly journals Effectiveness of adjunctive low frequency repetitive transcranial magnetic stimulation therapy over the left dorsolateral prefrontal cortex in refractory to medical treatment patients with obsessive-compulsive disorder: A double blind, randomized clinical trial

2021 ◽  
Author(s):  
Ghazal Jahanbakhsh ◽  
Alireza Hajseyedjavadi ◽  
Mahnaz Majidi
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Medical Treatment ◽  
Obsessive Compulsive Disorder ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Intervention Group ◽  
Low Frequency ◽  
Antipsychotic Agents ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Abstract Background: Obsessive-compulsive disorder (OCD) is a common neurotic disorder, In 2018 Application of repetitive transcranial magnetic stimulation (rTMS) for treating obsessive-compulsive disorder (OCD) has been approved by the Food and Drug Administration (28), since 2020 different methods has been tested, this study was designed to evaluate the effectiveness of adjunctive low frequency repetitive transcranial magnetic stimulation over the left dorsolateral prefrontal cortex in refractory to treatment patients suffering from obsessive compulsive disorder (OCD) Methods: This clinical trial was performed on 30 patients with OCD referred from the psychiatry clinic of 22 Bahman Hospital in Qazvin province from 2018 to 2020. Patients were randomly assigned to two groups. Intervention group received rTMS treatment at 1 Hz for 20 min (1200 (pulses / day) over the left DLPFC region as adjunctive to their medical treatment for 3 times a week and for 5 weeks while the control group received only sham condition in addition to their medical treatment. All the patients filled out the Yale Brown Questionnaire (YBOCS) Before the study, after sessions 5 and 10 during treatment, at the end of the treatment and 3 to 6 months after the treatment. The results were compared between the two groups using SPSS software version 16.Results: The mean score of post-intervention Yale Brown score was significantly lower in the intervention group. (P <0.05), it was also significant by gender (females), marital status ,taking antipsychotic agents in addition to the serotonergic agents and with more treatment sessions, within 3 to 6 months after intervention. Conclusion: adjunctive low frequency (1 Hz)rtms over the left DLPFC can be effective in reducing Yale Brown score in refractory to treatment patients suffering from OCD after 15 sessions. Gender, treatment sessions, usage of antipsychotic agents as adjuvant with standard treatment regiments, and marital status were identified as predictors for response to adjunctive rTMS therapy.

The Use of Repetitive Transcranial Magnetic Stimulation for Treatment of Obsessive-Compulsive Disorder: A Scoping Review. (Preprint)

2021 ◽  
Author(s):  
Medard Adu ◽  
Ejemai Eboreime ◽  
Adegboyega Sapara ◽  
Andrew J. Greenshaw ◽  
Pierre Chue ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Obsessive Compulsive Disorder ◽  
Scoping Review ◽  
Magnetic Stimulation ◽  
Depressive Disorders ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Relevant Literature ◽  
Invasive Procedure ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

BACKGROUND Background: Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive procedure in which brain neural activity is stimulated by direct application of a magnetic field to the scalp. rTMS is considered a therapeutic tool in various neuropsychiatric conditions. Since its approval in Canada in 2002 and despite its wide and continuous usage for the management of depressive disorders, knowledge on the use of rTMS for Obsessive-Compulsive Disorder (OCD) is sparse. OBJECTIVE Objectives: This scoping review seeks to; (i) explore the relevant literature available regarding the use of rTMS as a mode of treatment for OCD; (ii) To evaluate the evidence to support the use of rTMS as a treatment option for OCD. METHODS Method: We electronically conducted data search in five research databases (MEDLINE, CINAHL, Psych INFO, SCOPUS, and EMBASE) using all identified keywords and index terms across all the data bases to identify empirical studies and randomized controlled trials. We included articles published with randomized control designs which aimed at the treatment of OCD with rTMS. Only full-text published articles written in English were reviewed. Review articles on treatment for conditions other than OCD were excluded. RESULTS NA CONCLUSIONS Conclusion: The application of rTMS as a treatment intervention for OCD looks promising despite diversity in terms of outcomes and clinical significance. Further studies with well-defined stimulation parameters are needed in order to be able to draw a definite conclusion of its clinical effectiveness in the treatment of OCD.

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