Gene expression and promoter methylation of the XIAP-associated Factor 1 in renal cell carcinomas: Correlations with pathology and outcome

2007 ◽  
Vol 254 (2) ◽  
pp. 227-235 ◽  
Author(s):  
Carsten Kempkensteffen ◽  
Stefan Hinz ◽  
Mark Schrader ◽  
Frank Christoph ◽  
Ahmed Magheli ◽  
...  
2009 ◽  
Vol 181 (4S) ◽  
pp. 39-39
Author(s):  
James D Brooks ◽  
Hongjuan Zhao ◽  
Zhongming Ma ◽  
Robert Tibshirani ◽  
John P Higgins ◽  
...  

PLoS ONE ◽  
2009 ◽  
Vol 4 (6) ◽  
pp. e6039 ◽  
Author(s):  
Hongjuan Zhao ◽  
Zongming Ma ◽  
Robert Tibshirani ◽  
John P. T. Higgins ◽  
Börje Ljungberg ◽  
...  

APOPTOSIS ◽  
2007 ◽  
Vol 12 (9) ◽  
pp. 1645-1657 ◽  
Author(s):  
Sebastian Heikaus ◽  
Ercan Casliskan ◽  
Csaba Mahotka ◽  
Helmut Erich Gabbert ◽  
Uwe Ramp

Author(s):  
Mohammadreza Zarisfi ◽  
Tu Nguyen ◽  
Jessie R. Nedrow ◽  
Anne Le

AbstractAccording to data from the American Cancer Society, cancer is one of the deadliest health problems globally. Annually, renal cell carcinoma (RCC) causes more than 100,000 deaths worldwide [1–4], posing an urgent need to develop effective treatments to increase patient survival outcomes. New therapies are expected to address a major factor contributing to cancer’s resistance to standard therapies: oncogenic heterogeneity. Gene expression can vary tremendously among different types of cancers, different patients of the same tumor type, and even within individual tumors; various metabolic phenotypes can emerge, making singletherapy approaches insufficient. Novel strategies targeting the diverse metabolism of cancers aim to overcome this obstacle. Though some have yielded positive results, it remains a challenge to uncover all of the distinct metabolic profiles of RCC. In the quest to overcome this obstacle, the metabolic oriented research focusing on these cancers has offered freshly new perspectives, which are expected to contribute heavily to the development of new treatments.


2014 ◽  
Vol 32 (15_suppl) ◽  
pp. 4527-4527 ◽  
Author(s):  
Laurence Albiges ◽  
Nathalie Auger ◽  
Audrey Le Formal ◽  
Gregory Verhoest ◽  
Marc Olivier Timsit ◽  
...  

2014 ◽  
Vol 20 (13) ◽  
pp. 3411-3421 ◽  
Author(s):  
Laurence Albiges ◽  
Justine Guegan ◽  
Audrey Le Formal ◽  
Virginie Verkarre ◽  
Nathalie Rioux-Leclercq ◽  
...  

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