Very low bleeding rates with local thrombolytic therapy given during percutaneous endovenous intervention for the treatment of deep venous thrombosis

2011 ◽  
Vol 12 (3) ◽  
pp. e2
Author(s):  
Mohsen Sharifi ◽  
Curt Bay ◽  
Tariq Niazi ◽  
Farnaz Emrani ◽  
Farnoosh Rahimi ◽  
...  
Keyword(s):  
Thrombolytic Therapy ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Local Thrombolytic Therapy

Iliofemoral Deep Venous Thrombosis: Safety and Efficacy Outcome during 5 Years of Catheter-directed Thrombolytic Therapy

1997 ◽  
Vol 8 (3) ◽  
pp. 405-418 ◽  
Author(s):  
Haraldur Bjarnason ◽  
Janice R. Kruse ◽  
David A. Asinger ◽  
Gwen K. Nazarian ◽  
Charles A. Dietz ◽  
...  
Keyword(s):  
Thrombolytic Therapy ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Safety And Efficacy ◽  
Efficacy Outcome

Thrombolytic Therapy for Deep Venous Thrombosis?

JAMA ◽  
1999 ◽  
Vol 282 (22) ◽  
pp. 2164 ◽  
Author(s):  
McDonald K. Horne III
Keyword(s):  
Thrombolytic Therapy ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis

Risks and benefits of transcatheter thrombolytic therapy in patients with splanchnic venous thrombosis

2008 ◽  
Vol 100 (12) ◽  
pp. 1084-1088 ◽  
Author(s):  
Jasper H. Smalberg ◽  
Manon V. M. C. W. Spaander ◽  
Kon-Siong G. Jie ◽  
Peter M. T. Pattynama ◽  
Henk R. van Buuren ◽  
...  
Keyword(s):  
Thrombolytic Therapy ◽  
Venous Thrombosis ◽  
Fatal Outcome ◽  
High Rate ◽  
Venous Flow ◽  
Vein Thrombosis ◽  
Single Center Experience ◽  
Major Procedure ◽  
Local Thrombolytic Therapy ◽  
Minor Procedure

SummaryTranscatheter local thrombolytic therapy in patients with acute, extended splanchnic venous thrombosis is controversial. Here we present our single-center experience with transcatheter thrombolytic therapy in these patients. All consecutive patients (n=12) with acute,extended splanchnic venous thrombosis who underwent transcatheter thrombolytic therapy in our hospital, were included in this study. Thrombolytic therapy was successful for three thrombotic events and partially successful for four thrombotic events.Two patients developed minor procedure-related bleeding (17%).Six patients (50%) developed major procedure-related bleeding, with a fatal outcome in two. Transcatheter thrombolytic therapy in patients with acute, extended splanchnic vein thrombosis is found to be associated with a high rate of procedure-related bleeding. Therefore, thrombolysis should be reserved for patients in whom the venous flow cannot be restored by using conventional anticoagulant therapy or stent placement across the thrombosed vessel segment.H.L.A. Janssen and F.W.G. Leebeek are both Clinical Fellows of the Netherlands Organisation for Scientific Research (NWO).

Thrombolytic Therapy: A Comprehensive Review of Its Use in Clinical Medicine. Part II

1993 ◽  
Vol 8 (3) ◽  
pp. 115-129 ◽  
Author(s):  
William R. Bell ◽  
Michael B. Streiff
Keyword(s):  
Pulmonary Embolism ◽  
Thrombolytic Therapy ◽  
Cerebrovascular Disease ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Unstable Angina ◽  
Prosthetic Valve ◽  
Clinical Medicine ◽  
Comprehensive Review ◽  
Catheter Related Thrombosis

The second part of this comprehensive review of thrombolytic therapy in clnical medicien focuses on its use in a wide renge of thrombotic disorders, including pulmonary embolism, deep venous thrombosis, arterial thrombocmbolism, catheter-related thrombosis, arterial thrombocmbolism, catheter-relted thrombosis, and prosthetic valve occlusion. New experimental applications in the management of unstable angina and cerebrovascular disease are also discussed.

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