Evaluation of biomarker potential of cytochrome P450 1A (CYP1A) gene in the marine medaka, Oryzias melastigma exposed to water-accommodated fractions (WAFs) of Iranian crude oil

2013 ◽  
Vol 157 (2) ◽  
pp. 172-182 ◽  
Author(s):  
Ryeo-Ok Kim ◽  
Bo-Mi Kim ◽  
Dae-Sik Hwang ◽  
Doris W.T. Au ◽  
Jee-Hyun Jung ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Crude Oil ◽  
Marine Medaka ◽  
Water Accommodated Fractions ◽  
Oryzias Melastigma ◽  
Cytochrome P450 1A

Effects of benzo[a]pyrene on whole cytochrome P450-involved molecular responses in the marine medaka Oryzias melastigma

2014 ◽  
Vol 152 ◽  
pp. 232-243 ◽  
Author(s):  
Bo-Mi Kim ◽  
Jae-Sung Rhee ◽  
Chang-Bum Jeong ◽  
Su-Jae Lee ◽  
Yong Sung Lee ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Marine Medaka ◽  
Molecular Responses ◽  
Oryzias Melastigma

Whole Spectrum of Cytochrome P450 Genes and Molecular Responses to Water-Accommodated Fractions Exposure in the Marine Medaka

2013 ◽  
Vol 47 (9) ◽  
pp. 4804-4812 ◽  
Author(s):  
Jae-Sung Rhee ◽  
Bo-Mi Kim ◽  
Beom-Soon Choi ◽  
Ik-Young Choi ◽  
Rudolf S. S. Wu ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Marine Medaka ◽  
Molecular Responses ◽  
Cytochrome P450 Genes ◽  
Water Accommodated Fractions

Toxic Effects of Crude Oil Water Accommodated Fractions on the Cardiac Function of Marine Medaka (Oryzias melastigma) Embryo

2014 ◽  
Vol 644-650 ◽  
pp. 5220-5223
Author(s):  
Zhen Dong Zhang ◽  
Qi Lun Yan ◽  
Rui Rui Wang ◽  
Dao Yan Xu
Keyword(s):  
Cardiac Function ◽  
Crude Oil ◽  
Oil Pollution ◽  
Cardiac Contractility ◽  
Model Organism ◽  
Toxic Effects ◽  
Marine Medaka ◽  
Study Results ◽  
Water Accommodated Fractions ◽  
Medaka Embryo

The marine medaka Oryziasmelastigma was used as model organism to detect and evaluate the cardiac function alterations of medaka embryos due to oil exposure induced ecotoxicological effect in the present study. Results showed that the developing medaka heart was a sensitive target organ for the toxic effects of crude oil. Cardiac function of medaka embryos was clearly affected by exposure to WAF of crude oil after 24 hours exposure. Significant differences in cardiac structure and function of medaka embryo were found between exposed and control groups. The chemicals in crude oil slowed down the embryos heart rates, reduced cardiac contractility capability and causes irregular heartbeats. At higher exposure concentrations (7.2 mg/L), swelled and enlarged heart morphology, lower blood circulation and accumulation of blood around the heart area was found. These findings indicate that cardiac function of marine medaka embryo may be used as a toxicity model and biomarker for oil pollution.

Humic Substances and Crude Oil Induce Cytochrome P450 1A Expression in the Amazonian Fish SpeciesColossoma macropomum(Tambaqui)

2006 ◽  
Vol 40 (8) ◽  
pp. 2851-2858 ◽  
Author(s):  
Aline Y. O. Matsuo ◽  
Bruce R. Woodin ◽  
Christopher M. Reddy ◽  
Adalberto L. Val ◽  
John J. Stegeman
Keyword(s):  
Cytochrome P450 ◽  
Crude Oil ◽  
Humic Substances ◽  
Amazonian Fish ◽  
Cytochrome P450 1A

The inducibility of human cytochrome P450 1A by environmental-relevant xenobiotics in the human hepatoma derived cell line HepG2

2009 ◽  
Vol 28 (3) ◽  
pp. 370-378 ◽  
Author(s):  
Susanne Rudzok ◽  
Eike Schmücking ◽  
Carolin Graebsch ◽  
Olf Herbarth ◽  
Mario Bauer
Keyword(s):  
Cytochrome P450 ◽  
Cell Line ◽  
Human Hepatoma ◽  
Human Cytochrome ◽  
Cytochrome P450 1A
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