scholarly journals Identification and Characterization of MAVS, a Mitochondrial Antiviral Signaling Protein that Activates NF-κB and IRF3

Cell ◽  
2005 ◽  
Vol 122 (5) ◽  
pp. 669-682 ◽  
Author(s):  
Rashu B. Seth ◽  
Lijun Sun ◽  
Chee-Kwee Ea ◽  
Zhijian J. Chen
Keyword(s):  
Antiviral Signaling ◽  
Signaling Protein ◽  
Mitochondrial Antiviral Signaling ◽  
Identification And Characterization ◽  
Mitochondrial Antiviral Signaling Protein

The Q41R mutation in HCV-protease enhances the reactivity towards MAVS by suppressing non-reactive pathways

2021 ◽  
Author(s):  
Chen Zheng ◽  
Markus Schneider ◽  
Antoine Marion ◽  
Iris Antes
Keyword(s):  
Significant Enhancement ◽  
New Mutation ◽  
Antiviral Signaling ◽  
Signaling Protein ◽  
Hcv Protease ◽  
Mitochondrial Antiviral Signaling ◽  
Experimental Findings ◽  
Mitochondrial Antiviral Signaling Protein

Recent experimental findings pointed out a new mutation in HCV protease, Q41R, responsible for a significant enhancement of the enzyme’s reactivity towards the mitochondrial antiviral-signaling protein (MAVS). The Q41R mutation...

Sign in / Sign up

Export Citation Format

Share Document