Tinkering With a Tarnished Technique: Isn't It Time to Abandon Celiac Plexus Blockade for the Treatment of Abdominal Pain in Chronic Pancreatitis?

2012 ◽  
Vol 10 (2) ◽  
pp. 106-108 ◽  
Author(s):  
C. Mel Wilcox
2020 ◽  
Vol 28 (1) ◽  
pp. 32-38
Author(s):  
Pedro Moutinho-Ribeiro ◽  
Pedro Costa-Moreira ◽  
Ana Caldeira ◽  
Sílvia Leite ◽  
Susana Marques ◽  
...  

Abdominal pain related to pancreatic disease is often extremely disabling. Endoscopic ultrasound (EUS)-guided celiac plexus block (CPB) is used to control pain associated with chronic pancreatitis. EUS-guided celiac plexus neurolysis (CPN) is typically used to reduce pain associated with pancreatic cancer and can be considered early at the time of diagnosis of inoperable disease. EUS-guided celiac plexus interventions have been shown to be significantly effective in pancreatic pain relief, which is achieved in approximately 70–80% of patients with pancreatic cancer and in 50–60% of those with chronic pancreatitis. Serious complications from CPB and CPN are rare. Most frequent adverse events are diarrhoea, orthostatic hypotension, and a transient increase in abdominal pain. In this article, the Portuguese Group for Ultrasound in Gastroenterology (GRUPUGE) presents an updated perspective of the potential role of EUS-guided celiac plexus interventions, addressing the selection criteria and technical issues of different techniques and analysing recent data on their safety and efficacy.


Pancreas ◽  
2008 ◽  
Vol 37 (4) ◽  
pp. 477
Author(s):  
M. S. Kaufman ◽  
G. Singh ◽  
S. Das ◽  
J. A. Erber ◽  
C. Micames ◽  
...  

2007 ◽  
Vol 65 (5) ◽  
pp. AB209 ◽  
Author(s):  
Terrance M. O'Toole ◽  
Norah J. Shire ◽  
Shailendra S. Chauhan ◽  
Nathan Schmulewitz

2016 ◽  
Author(s):  
Jianguo Cheng

Early diagnosis of chronic pancreatitis is possible by combining clinical information with pancreatic function testing, endoscopic ultrasonography, histology, and traditional imaging techniques such as magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography (ERCP). Such an approach helps improve the sensitivity and specificity of these complementary modalities. Pain management of chronic pancreatitis involves multidisciplinary and multimodal approaches. Behavioral modifications such as alcohol cessation, nutritional optimization, and cognitive-behavioral therapy play a significant role for better long-term outcomes. Pharmacologic management is directed at relieving both psychological and physical symptoms, and combination pharmacotherapies are often needed to address pancreatic deficiency, abdominal pain, and psychological disorders. Interventional approaches to celiac plexus and splanchnic nerve blocks and denervation (radiofrequency ablation, endoscopic or surgical denervation) may provide significant and prolonged pain relief. Neuromodulation in the form of spinal cord stimulation is a viable option for long-term pain relief. Managing complications of chronic pancreatitis, such as gastrointestinal complications (peptic ulcer, bile duct stenosis), pseudocysts, malnutrition, depression, diabetes, and painful diabetic neuropathy, is an integral part of comprehensive treatment and requires close collaboration between members of a multidisciplinary team.   This review contains 1 figures, 2 tables and 64 references Key words: behavioral modifications, celiac plexus, chronic abdominal pain, chronic pancreatitis, interventional therapy, pharmacologic modulation, splanchnic nerves, surgical intervention


2020 ◽  
Vol 88 (3) ◽  
pp. 921-927
Author(s):  
AHMED I. EBEED, M.D.; HAITHAM M. FODA, M.D. ◽  
SHERIF K. ARAFA, M.D.; AMIR A. EL SAYED, M.D.

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