scholarly journals Among Patients with Undetectable Hepatitis B Surface Antigen and Hepatocellular Carcinoma, a High Proportion Has Integration of HBV DNA into Hepatocyte DNA and No Cirrhosis

2020 ◽  
Vol 18 (2) ◽  
pp. 449-456 ◽  
Author(s):  
Danny Ka-Ho Wong ◽  
Serene Ching Yan Cheng ◽  
Loey Lung-Yi Mak ◽  
Elvis Wai-Pan To ◽  
Regina Cheuk-Lam Lo ◽  
...  
2013 ◽  
Vol 38 (3) ◽  
pp. 104-107 ◽  
Author(s):  
MA Mahtab ◽  
SMF Akbar ◽  
S Rahman

Hepatitis B surface antigen (HBsAg) is regarded as sole marker of hepatitis B virus (HBV) infection in Bangladesh and most other developing countries. However, some HBV-negative subjects may harbor HBV DNA and transfusion of their blood may cause HBV infection in recipients. HBV DNA was checked in 20 patients with cryptogenic liver cirrhosis, 10 patients with hepatocellular carcinoma without any known etiology, and 10 apparently healthy subjects with elevated levels of serum alanine aminotransferase (ALT). HBV DNA was detected in 8 of 20 patients with cryptogenic liver cirrhosis, 1 of 10 patients with hepatocellular carcinoma, and 2 of 10 apparent healthy subjects with elevated ALT. However, all of them were negative for HBsAg in the sera. This study indicates that some additional mechanisms should be developed for detection of HBsAg-negative HBV-infected subjects for efficient control and management of HBV infection in Bangladesh. DOI: http://dx.doi.org/10.3329/bmrcb.v38i3.14337 Bangladesh Med Res Counc Bull 2012; 38(3): 104-107 (December)


2017 ◽  
Vol 67 (5) ◽  
pp. 902-908 ◽  
Author(s):  
Terry Cheuk-Fung Yip ◽  
Henry Lik-Yuen Chan ◽  
Vincent Wai-Sun Wong ◽  
Yee-Kit Tse ◽  
Kelvin Long-Yan Lam ◽  
...  

1982 ◽  
Vol 1 (10) ◽  
pp. 1213-1216 ◽  
Author(s):  
Y. Wang ◽  
M. Schäfer-Ridder ◽  
C. Stratowa ◽  
T.K. Wong ◽  
P.H. Hofschneider

2012 ◽  
Vol 18 (8) ◽  
pp. 995-998 ◽  
Author(s):  
Tammy T. Hshieh ◽  
Vinay Sundaram ◽  
Robert M. Najarian ◽  
Douglas W. Hanto ◽  
Seth J. Karp ◽  
...  

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